Abstract: An implant to be inserted in the disk space between a lower vertebra and an upper vertebra. The implant comprises a body having a lower surface and an upper surface, and an aperture extending through the body in the direction of the height of the body from a lower side of the body to an upper side of the body. The body is arranged to reduce its height permanently under the load the body is exposed to between a lower vertebra and an upper vertebra.

Abstract: The present invention relates to porous bone filling materials prepared by sintering bioactive glass fibers in order to achieve a three dimensional block with interconnecting porosity. Due to the osteoconductive properties the bioactive glass fibers, in block form are an ideal scaffold for new tissue (e.g. bone or cartilage) formation to occur. The manufacturing parameters can be adjusted to achieve porosities as high as 90 vol-%, or the manufacturing parameters can be adjusted to prepare strong porous blocks useful in load bearing application.

Abstract: A device for removal of fastening means from human tissue. The device comprises a shaft having proximal and distal ends and a longitudinal centre line. The distal end comprises a thread section having a centre line that is coaxial with the longitudinal centre line of the shaft and a left-hand thread that screws itself around the centre line, and a counter surface that is disposed outside the thread and has a surface component direction which intersects one of said centre lines. The counter surface is disposed so as to make contact with the fastening means to be removed when the thread is rotated into a hole in the fastening means.

Abstract: A bone grafting material, a method of producing the same, and an implant. The bone grafting material comprises a porous carrier of ceramic or glass ceramic or glass material and at least one pyrrolidone arranged in the carrier.

Abstract: The present invention relates to novel mutants of bone morphogenetic proteins (BMPs) useful as inhibitors of heterotopic ossification. Specifically, the present invention relates to novel mutants containing only the entire region involved in the formation of finger 2 including the wrist epitope of a BMP with a specific cysteine residue or specific cysteine residues replaced by a different amino acid. The present invention also relates pharmaceutical compositions containing these mutants and to the use of the mutants and pharmaceutical compositions in therapy.

Abstract: A surgical implant made of a polymer, copolymer, polymer mixture or polymer composite that dissolves in the organ system. The manufacturing material is dyed with the coloring agent D&C Violet No. 2 or D&C Green No. 6. Preferably, the amount of the coloring agent is at most approximately 0.03 percent by weight and the implant is sterilized by radiation.

Abstract: A fastener for the treatment of fractures and the materials for production thereof. The fastener having a head with a contact portion for an installation tool and an attaching part having a treaded portion. The threads of the threaded portion are 5 to 20 % of the height of the outer diameter of the thread. The material for producing the fastener is a blend containing a biodegradable base material and one or more copolymer additives so that at room temperature the ductility of the blend is substantially higher than that of the pure base material. The base material may be a biodegradable polymer and/or a copolymer.

Abstract: A system and method for stabilizing the spine. The system comprises a fixation screw with a threaded section, and a fixation plate with a top and bottom surface. The fixation plate has a pre-drill hole arranged on the side of the top surface, and with the pre-drill hole, an actual fixation hole is made to the plate. The fixation hole is made when the plate is arranged at its future fixation point on the surface of bone tissue such that the fixation hole forms a first angle relative to the plate, whose size is selectable from several alternatives within certain limit values. The threaded section of the fixation hole is made during the same work phase as the threaded section in the bone tissue.

Abstract: A suture anchor, an insertion tool for inserting a suture anchor, and a device for internal working of hole in bony tissue. The anchor comprises an anchor body having a longitudinal cross-section defined by a perimeter. The perimeter comprises at least one tissue-intruding edge formed between the first side and the second side of the perimeter. The intruding edge is arranged to penetrate the tissue during a rotating motion of the anchor in said opening. The anchor further comprises an abutment surface, arranged substantially on the opposite side of the anchor body in relation to said intruding edge. The first side of the intruding edge is arranged to connect with the abutment surface by a connecting part of the perimeter having the shape of a substantially curved piece in said longitudinal cross-section.

Abstract: A biodegradable implant and a method for manufacturing one. The implant comprises a matrix component containing at least one biodegradable polymer or copolymer and a pyrrolidone plasticizer that is adapted to reduce the rigidity of the implant. The plasticizer substantially exits from the implant after coming into contact with tissue fluids of the organ system in such a manner that the bending resistance of the implant prior to the insertion of the implant into the organ system is lower than after its insertion into the organ system.

Abstract: An instrument for shaping a mouth part of a drilled tunnel provided in a bone. The instrument includes a shaft having a longitudinal axis and a first and a second end. The first end of the shaft is provided with a projection, which includes a blade for shaping the mouth part of the drilled tunnel when the instrument is turned around the longitudinal axis of the shaft. The instrument is asymmetric at an intersecting surface perpendicular to the longitudinal axis and intersecting with the blade, the instrument thus shaping the surfaces surrounding the first end only substantially within an area corresponding with a turning angle of such a turning movement.

Abstract: A surgical implant shaping instrument, a surgical system, and a method for shaping a surgical implant into conformance with a surface of a bony tissue. The implant shaping instrument comprises shaping means arranged in a body part, said shaping means comprising a press element having a flexible structure configured to be pushed against an implant arranged onto an underlying bony tissue so that said implant at least substantially conforms with the shape of the underlying bony tissue.

Abstract: A storage for surgical fixation devices and an arrangement for the storage for surgical fixation devices. The storage for fixation devices comprises fixation device slots for at least one fixation device and a guide that is arranged to guide a counter element of an installation tool to a contact section of a fixation device located in the fixation device slot. The arrangement comprises a space for the fixation device storage, to which the storage for fixation devices can be arranged, and a guide for an installation tool, the guide being arranged to guide a counter element of the installation tool to a contact section of a fixation device located in the fixation device slot.

Abstract: A cutting device for cutting fixation devices used in surgical operations and made of polymer material or polymer composite. The cutting device comprises a blade arrangement, which comprises one or more blades, one or more guides, which comprise a fixation device space, in which the fixation device to be cut is intended to be arranged, means for using the blade arrangement for cutting the fixation device arranged in the guide. The guide is arranged obliquely with respect to the shear plane of blade arrangement so that a cutting surface which is oblique with respect to the longitudinal axis of the fixation device is formed at the tip of the cut fixation device.

Abstract: A bone grafting material, a method of producing the same, and an implant. The bone grafting material comprises a porous carrier of ceramic or glass ceramic or glass material and at least one pyrrolidone arranged in the carrier.

Abstract: Novel polymer compositions that are useful in the manufacture of medical implants, implants having osteogenic properties and methods of making said implants are disclosed. Polymer compositions comprise a base material including a polymer matrix of resorbable polymer(s) or copolymer(s), and N-methyl-2-pyrrolidone (NMP), wherein NMP is present in an amount imparting osteogenic properties for the composition.

Abstract: Novel polymer compositions that are useful in the manufacture of medical implants, implants having osteogenic properties and methods of making said implants are disclosed. Polymer compositions comprise a base material including a polymer matrix of resorbable polymer(s) or copolymer(s), and N-methyl-2-pyrrolidone (NMP), wherein NMP is present in an amount imparting osteogenic properties for the composition.

Abstract: A soft-tissue screw, comprising: an elongated body made of a biodegradable material and having a proximal and distal part, a channel arranged to the body in its axial direction, a first threaded part arranged to the distal part of the body, a second threaded part arranged to the proximal part of the body, a leading end arranged to the distal part, the leading end being in shape a rotationally symmetrical piece that is cut obliquely across so that a planar cut surface is created on the end, and a substantially unthreaded intermediate part arranged between the first and second threaded parts.

Abstract: A bone plate for supporting bone. At least one shaping area reducing the shaping resistance of the shape of the bone plate and the bending and/or torsional resistance of the body is arranged in the section of the bone plate between fixation holes.

Abstract: An instrument for shaping a mouth part of a drilled tunnel provided in a bone. The instrument includes a shaft having a longitudinal axis and a first and a second end. The first end of the shaft is provided with a projection, which includes a blade for shaping the mouth part of the drilled tunnel when the instrument is turned around the longitudinal axis of the shaft. The instrument is asymmetric at an intersecting surface perpendicular to the longitudinal axis and intersecting with the blade, the instrument thus shaping the surfaces surrounding the first end only substantially within an area corresponding with a turning angle of such a turning movement.