Abstract: Intravenous solutions are manufactured and distributed in batches by gathering raw materials and components for manufacturing containers for intravenous solutions, and active ingredient but excluding solvent. In a central manufacturing plant, critical steps are performed such as dispensing predetermined amounts of the active ingredient into holders. The products of the central manufacturing plant are packed into shipping containers which are distributed to respective decentralized manufacturing plants where the contents are unpacked, manufacture of containers is completed, solvent is obtained, intravenous solution is mixed, and the containers are filled, hermetically sealed and sterilized in an autoclave.