Patents Assigned to Inmunologia Y Genetica, S.A.
  • Patent number: 5498413
    Abstract: Method for the production of a subunit vaccine against porcine parvovirus (PPV). The method is comprised of a first step wherein a recombinant protein VP2 of PPV is obtained by using the replication of a recombinant baculovirus wherein the gene corresponding to VP2 has been previously inserted in cells of a permissive host. The protein VP2 obtained in this invention has the capacity of forming empty chimeric capsids with high immunogenicity and can be provided as a vaccine formulation for protecting pigs against PPV infection. The recombinant baculovirus AcMNPV.pPPVEx8 expresses the VP2 of PPV in conditions making possible the formation of pseudo-viral capsids.
    Type: Grant
    Filed: January 27, 1993
    Date of Patent: March 12, 1996
    Assignee: Inmunologia Y Genetica, S.A.
    Inventors: Jose I. Casal Alvarez, Elena Cortes Valdes, Ana I. Ranz Casares, Carmen Vela Olmo, Kristian Dalsgaard