Patents Assigned to Innate Biotherapeutics, LLC
  • ß-1,6-glucan therapeutic antibody conjugates
    Patent number: 11865135
    Abstract: The present invention encompasses embodiments in which a therapeutic antibody is conjugated to ?-1,6-glucan oligomers. Thus, the present invention includes, among other things, compositions including a therapeutic antibody conjugated to one or more ?-1,6-glucan oligomers. The present invention further includes, among other things, methods of making and/or using such ?-1,6-glucan conjugates. In certain embodiments, a ?-1,6-glucan conjugate of the present invention is useful as a therapeutic or in a method of therapy.
    Type: Grant
    Filed: December 5, 2017
    Date of Patent: January 9, 2024
    Assignee: Innate Biotherapeutics, LLC
    Inventors: Gabriel Oscar Reznik, John James Kane, James Michael Siedlecki, Zuzana Dostalova, Isabelle Sansal-Castellano, Ifat Rubin-Bejerano, Hua Miao, Eric Steven Furfine
  • Immunomodulating beta-1,6-D-glucans
    Patent number: 10266609
    Abstract: This invention relates to modifications of ?-1,6-D-glucans, e.g., structures according to Formula (I), and the ability of these compositions to modulate an immune response.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: April 23, 2019
    Assignee: Innate Biotherapeutics, LLC
    Inventors: James Michael Siedlecki, Gabriel Oscar Reznik, John James Kane, Hua Miao, Arthur F. Kluge, Ifat Rubin-Bejerano