Patents Assigned to Inno Bio-Drug Development Limited
  • Peptide and its derivatives capable of inhibiting replication of hepatitis V virus in human adipose-derived stem cells and hepatocytes
    Patent number: 11254706
    Abstract: Hepatitis C virus (HCV) infection is a leading cause for liver cirrhosis and hepatocellular carcinoma worldwide2. Current therapeutic regimens are usually poorly tolerated and only effective in a proportion of infected individuals. We discovered a peptide with sequence of DEAQETAVSSHEQD (SEQ ID NO: 1), a fragment of rabbit ?1-antiproteinase F, and its derivatives DEAQETAVSSHEQ (SEQ ID NO: 2) and QETAVSSHEQD (SEQ ID NO: 3), significantly inhibit serum-borne HCV replication in hADSC and human hepatocytes.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: February 22, 2022
    Assignee: Inno Bio-Drug Development Limited
    Inventor: Chen-Lung Lin