Abstract: This application discloses an embodiment of a scanning drive motor and pre-tightening method, rotating mirror, LiDAR, and mobile device. The scanning drive motor includes an integrated bearing structure, a mover assembly, and a stator assembly. The integrated bearing structure comprises a first bearing, a second bearing, and a rotating shaft. The first bearing includes a first inner ring and a first outer ring, and the second bearing includes a second inner ring and a second outer ring. The first bearing and the second bearing are both sleeved on the rotating shaft, and the first inner ring and the second inner ring are both connected to the rotating shaft. The mover assembly includes a mover. The stator assembly includes a stator and a stator base. The stator is connected to the stator base, which forms a bearing chamber. The scanning drive motor is more convenient to assemble.

Abstract: The present invention relates to a humanized antibody specific for CD22 and a chimeric antigen receptor using the same, and more specifically, to a humanized antibody specifically binding to CD22, a chimeric antigen receptor including the antibody, a CAR-T cell expressing the chimeric antigen receptor, a pharmaceutical composition including the same and a method for preventing or treating a disease mediated by B cells using the pharmaceutical composition. In the present invention, it was confirmed that the CD22-CAR-T cells prepared based on a humanized antibody specifically binding to CD22 effectively recognized a CD22 antigen to activate CAR-T cells, and that the CD22-CAR-T cells effectively killed cells expressing CD22. Furthermore, the humanized antibody-based CD22-CAR-T cells specifically binding to CD22 of the present invention can be usefully utilized as a composition for preventing or treating a disease related to the expression of CD22 or a disease related to B cells.

Abstract: The present invention relates to an apparatus for diagnosing solid cancers comprising lung cancer, pancreatic cancer, bile duct cancer, colorectal cancer, breast cancer, gastric cancer, brain tumors, kidney cancer, liver cancer, and cervical cancer. More specifically, the apparatus comprises: a concentration measurement unit for measuring the concentration of each of acyl-carnitine (AC), nudifloramide (2PY), and lysophosphatidylcholine (LPC) from a biological sample; a pre-processing unit for pre-processing the measured concentrations; and a diagnosis unit for determining the diagnosis information of cancer through linear discriminant analysis using the pre-processed concentrations.

Abstract: The present invention relates to a humanized antibody specific for CD22 and a chimeric antigen receptor using the same, and more specifically, to a humanized antibody specifically binding to CD22, a chimeric antigen receptor including the antibody or a CD19xCD22 antibody, a CAR-T cell expressing the chimeric antigen receptor, and a pharmaceutical composition including the same for preventing or treating a disease mediated by B cells. In the present invention, it was confirmed that the CD22-CAR-T cells and bispecific CD19xCD22-CAR-T cells prepared based on a humanized antibody specifically binding to CD22 effectively recognized a CD22 antigen to activate CAR-T cells, and that the CD22-CAR-T cells and bispecific CD19xCD22-CAR-T cells effectively killed cells expressing CD22.

Abstract: A method for manufacturing a profiled section made of a thermally insulating composite material. A thermoset matrix is injected into an injection box where continuous natural fiber rovings circulate. The continuous natural fiber rovings and a portion of the thermoset matrix are pultruded. The natural fiber volume ratio is between 50 and 70% and a natural fiber mass ratio is between 55 and 75%. During the injection step, the ratio of natural fibers can be adapted so that the composite material has a conductivity of less than 0.30. The continuous natural fiber rovings can be twisted before the steps of injecting and pultruding. Preferably, during the twisting step, a number of turns per meter of between 10 and 30 is transmitted to the continuous natural fiber rovings.