Abstract: A driver protective device for a two-wheeled vehicle according to the present invention, includes: a main frame including a mounting frame which is mounted on a body of the two-wheeled vehicle, and a panel frame which is fixed to the mounting frame and has a front transparent panel installed therein; a storage box which is mounted on a rear portion of the two-wheeled vehicle; and an attachable protection panel including an upper panel which is attached to or detached from one end of the panel frame of the main frame, and a back panel which is attached to or detached from one side of the storage box, wherein the upper panel and the back panel are pivotly connected to each other.