Patents Assigned to INNOTESTO BVBA
  • Methods for treating Parkinson's disease
    Patent number: 9737526
    Abstract: An oromucosal solution comprising about 1-8% (w/v) apomorphine or a pharmaceutical acceptable salt thereof solubilised in a non-aqueous carrier containing at least about 50% (v/v) of propylene glycol. A small volume (25-250 ?L) of said solution containing about 1-12 mg apomorphine may be administered upon demand to treat motor fluctuations during off periods in patients suffering from Parkinson's disease. The solution may also be used for the treatment of sexual dysfunction.
    Type: Grant
    Filed: November 7, 2016
    Date of Patent: August 22, 2017
    Assignee: INNOTESTO BVBA
    Inventor: Franciscus Wilhelmus Henricus Maria Merkus
  • Testosterone solutions for the treatment of testosterone deficiency
    Patent number: 9498436
    Abstract: Solutions of testosterone for oromucosal administration providing an increase in serum testosterone levels in subjects deficient in endogenous testosterone levels, and therapeutic methods for providing an increase in serum testosterone levels and methods for treating a disease or a symptom associated with deficient endogenous levels of testosterone.
    Type: Grant
    Filed: August 9, 2011
    Date of Patent: November 22, 2016
    Assignee: INNOTESTO BVBA
    Inventor: Franciscus Wilhelmus Henricus Maria Merkus
  • NASAL COMPOSITIONS STIMULATING CILIARY ACTIVITY
    Publication number: 20160271135
    Abstract: Nasal compositions, comprising an aqueous solution containing caffeine and/or theobromine in a total concentration of up to about 0.5% (w/v) and an aqueous carrier having a pH of about 6-8 and comprising physiologically acceptable salts of sodium, potassium and calcium. The nasal composition when used as a nasal spray or as nasal drops or irrigation fluid is able to clean the nasal passages and to stimulate nasal mucociliary clearance and, in contrast to nasal decongestants, may be used on a daily-basis for a period longer than 5 days.
    Type: Application
    Filed: October 30, 2014
    Publication date: September 22, 2016
    Applicants: INNOTESTO BVBA, Veramed B.V.
    Inventors: Franciscus Wilhelmus Henricus Maria Merkus, Bart Merkus
  • Oromucosal liquid estradiol compositions
    Patent number: 9402811
    Abstract: The present invention relates to low dose estradiol solutions for oromucosal administration suitable in replacement therapy or suppletion of low estradiol levels and also for preventing, alleviating or treating symptoms associated with low endogenous levels of estradiol in female subjects.
    Type: Grant
    Filed: January 4, 2013
    Date of Patent: August 2, 2016
    Assignee: INNOTESTO BVBA
    Inventor: Franciscus Wilhelmus Henricus Maria Merkus
  • Oromucosal Apomorphine Compositions
    Publication number: 20150272872
    Abstract: An oromucosal solution comprising about 1-8% (w/v) apomorphine or a pharmaceutical acceptable salt thereof solubilised in a non-aqueous carrier containing at least about 50% (v/v) of propylene glycol. A small volume (25-250 ?L) of said solution containing about 1-12 mg apomorphine may be administered upon demand to treat motor fluctuations during off periods in patients suffering from Parkinson's disease. The solution may also be used for the treatment of sexual dysfunction.
    Type: Application
    Filed: September 27, 2013
    Publication date: October 1, 2015
    Applicant: INNOTESTO BVBA
    Inventor: Franciscus Wilhelmus Henricus Maria Merkus
  • Testosterone Solutions for the Treatment of Testosterone Deficiency
    Publication number: 20130143851
    Abstract: Solutions of testosterone for oromucosal administration providing an increase in serum testosterone levels in subjects deficient in endogenous testosterone levels, and therapeutic methods for providing an increase in serum testosterone levels and methods for treating a disease or a symptom associated with deficient endogenous levels of testosterone.
    Type: Application
    Filed: August 9, 2011
    Publication date: June 6, 2013
    Applicant: INNOTESTO BVBA
    Inventor: Franciscus Wilhelmus Henricus Maria Merkus