Abstract: A high capacity solid phase for bioaffinity assays and other solid phase applications prepared by coating a solid support with an analyte-specific biomolecule in the presence of a zwitterionic additive is described. Structures prepared according to the invention provide high capacity solid phases with enhanced binding properties, which are advantageous for any solid phase based assay.

Abstract: This invention relates to a luminescent lanthanide chelate comprising a lanthanide ion and a chelating ligand of formula (I) wherein R1 is selected from the group consisting H, —COOH, —COO?, —CH2COOH and —CH2COO?; G1 is a group consisting of one or two moieties each moiety being selected from the group consisting of ethynediyl, ethenylene, phenylene, biphenylene, naphthylene, pyridylene, pyrazinylene, pyrimidinylene, pyridazinylene, furylene, thienylene, pyrrolylene, imidazolylene, pyrazolylene, thiazolylene, isothiazolylene, oxazolylene, isoxazolylene, fyrazanylene, 1,2,4-triazol-3,5-ylene and oxadiazolylene; G2 for coupling to a biospecific binding reactant is selected from the group consisting of amino, aminooxy, carbonyl, aldehyde or mercapto groups and activated forms made of them; Z is selected from the group consisting of carboxyalkyl amine, ether, thioether, carbonyl and unsubstituted or substitute methyl (—CR2—) wherein group R2 is selected from the group consisting of H, methyl, ethyl and carbo

Abstract: A sample handling method, in which the information on the sample to be examined is transferred throughout the entire measuring process by transferring the sample cup. The sample cups are handled in two independently operating drums, in which case at least two different handling phases can be carried out simultaneously in the measuring device. The diagnostic measuring device comprises a cassette drum, on the circumference of which the sample cup cassettes containing sample cups have been placed. The sample cup is fed to the first handling drum, which is simultaneously an incubation drum. After that the sample cup is transferred to a second handling drum, where washing, drying, measuring and discharge of the sample cup are carried out. The drums have been placed near each other, overlapping so that the transfers of the sample cup can be performed directly from one drum to another by means of transfer plungers.

Abstract: The invention relates to a novel competitive or non-competitive immunoassay comprising the steps of immobilizing an assay specific component on a solid phase in a reaction well, adding a labelled assay specific component, drying said components, adding the sample containing the marker to be analyzed, allowing the marker to react with the assay specific components, and detecting the signal from the label. Furthermore, the invention relates to a device useful in carrying out the novel assay.