Abstract: The invention relates to suturing instrument for joining two edges of biological tissue together. The instrument includes a housing (1) in which there is movably arranged an arcuate suture needle (16) having a point (17) arranged to penetrate the tissue, and the suture thread (18) connected to the suture needle. Drive means (3,8,11,12,13) are provided for causing the needle (16) to move in a manner such as to pass the thread thereon through one of the tissue edges and up through the other of the tissue edges, to join the two edges together with a firm suture. The novel feature of the instrument resides in the fact that the end of the suture needle remote from the point (17) thereof is connected to the suture thread and is arranged to be driven in the direction of the point (17) in a closed path by the drive means.