Abstract: An infusion port for subcutaneous placement and dialysis procedures is shown and described as including two chambers, two corresponding large area membrane access panels, and two corresponding barbs providing access between the infusion port and a patient's blood circulatory system. A valve selectively couples the chambers and the barbs in one state, and in another state isolates the barbs and couples directly the two chambers. The valve can operate externally by pressure applied to patient's skin. Hemodialysis is performed in the first state, and in the second state the port is flushed clean of residual blood by injecting cleansing fluid into one chamber and withdrawing it from the other. Also disclosed, an access needle includes a tube carrying a removable penetration pin. The tube fluidly couples to an external barb. The needle is fluidly coupled to the infusion port by driving the needle through the skin of the patient and membrane of the infusion port.