Abstract: Disclosed are cell penetrating peptides and compositions comprising such peptides that can be used to deliver agents to various cell types.

Abstract: Disclosed are systems and methods utilizing an infrared probe and discriminating software to rapidly discriminate abnormal tissue processes from normal tissue during surgery, physical examination of in-situ lesions, and in the assessment of biopsy and resected tissue specimens. Examples demonstrate discrimination of cancerous from noncancerous tissues. The discriminating software, i.e. the metrics, algorithms, calibrant spectra, and decision equations, allows tissue to be identified as abnormal or normal using a minimum of infrared (IR) wavelengths in order to be measured rapidly. The probe records IR metrics approximately 1000 times faster than current commercial instruments, i.e. on a timescale fast enough for clinical use. The probe uses a tunable mid-infrared laser with a small set of selected wavelengths that are optimized for detecting the chemical and molecular signatures of tissue specific lesions to include, but not limited to, cancer, preneoplasia, intracellular accumulations (e.g.

Abstract: Aspects herein are directed to nucleating skyrmions in spintronic materials by dynamic manipulation of an in-plane magnetic field and related design of prototype devices for spintronic memory and processing. Different from conventional phase transition methods, nucleating and manipulating skyrmion using in-plane fields and spin current pulses is described. For example, in a material with rotatable anisotropy and asymmetry geometric confinement, a skyrmion can be nucleated by switching the in-plane fields. This has been experimentally confirmed in a centrosymmetric magnet, Fe3Sn2, with an engineered thickness gradient.

Abstract: An ultra-compact lens system for fluorescence imaging includes a first lens, a second lens and third lens. The first lens has a Meniscus shape including first and second surfaces facing each other. The first surface is concave, and each of the first and second surfaces is an aspherical surface. The second lens is adjacent to the first lens and includes third and fourth surfaces facing each other. Each of the third and fourth surfaces is convex and aspherical surface. The third lens is adjacent to the second lens and includes fifth and sixth surfaces facing each other. Each of the fifth and sixth surfaces is concave and aspherical surface.

Abstract: Disclosed herein are compositions and methods that involve inserting connector protein channels of bacteriophage DNA packaging motors into copolymeric membranes via liposome-polymer fusion, which can be used as nanopore sensors for biomedical applications such as high throughput protein sequencing or cancer diagnosis. For example, disclosed are compositions comprising a copolymeric membrane into which a connector protein channel of a bacteriophage packaging motor has been inserted.

Abstract: Advancing beyond Interpretability and explainability approaches that may uncover what a Deep Neural Network (DNN) models, i.e., what each node (cell) in the network represents and what images are most likely to activate the model provide a mimicked type of learning of generalization applicable to previously unseen samples. The approach provides an ability to detect and circumvent adversarial attacks, with self-verification and trust-building structural modeling. Computing systems may now define what it means to learn in deep networks, and how to use this knowledge for a multitude of practical applications.

Abstract: Systems and methods are provided that allow developers to quickly and easily develop augmented reality (AR) applications that enrich the real-world with data from the cloud. Given that the development of an AR application is a complex and time-consuming process, the systems and methods described herein allow software developers to concisely describe their needs in a succinct program, written in the QWL domain-specific language. The systems and methods take this program and automatically generate an AR application.

Abstract: In a diagnosis system using fluorescence information and acidity information and a diagnosis method using the same, the diagnosis system includes a fluorescence information obtainment part, an acidity information obtainment part, a derivation part, an acidity information calculation part and a diagnostic part. The fluorescence information obtainment part is configured to obtain fluorescence information from a sample and a specimen subject to diagnosis. The acidity information obtainment part is configured to obtain acidity information from the sample. The derivation part is configured to derive a correlation between the fluorescence information and the acidity information. The acidity information calculation part is configured to calculate acidity information of the specimen based on the fluorescence information obtained from the specimen, using the correlation.

Abstract: A method for evaluating for the presence of the COVID disease by detecting one or more biomarkers using a breathalyzer. The breath sample taken from the subject is passed over a sensor which changes resistance in the presence of nitric oxide as a function of concentration. The resistance pattern of the subject having the COVID disease will have a distinct shape, approximating the appearance of the small Greek letter omega (?). Test results can be generated in less than a minute.

Abstract: A finger for a robotic gripper may include a flexible backbone, a plurality of jamming layers, and a membrane bag. The backbone may have a first side, a second side, a third side, and a fourth side. The backbone may include a flexible beam, and a plurality of branches attached to the flexible beam and spaced apart from one another. Each branch may include a first end surface extending along the first side, and a second end surface extending along the second side. The first end surfaces may collectively extend along a majority of the first side, and the second end surfaces may collectively extend along a majority of the second side. The jamming layers may be positioned along the third side or the fourth side. The membrane bag may be positioned over the jamming layers.

Abstract: Disclosed herein are systems, methods and computer-program products to create synthetic immunohistochemistry (IHC) stained digital slides generated using artificial neural networks (ANNs). In some implementations, the created digital slides can be used as a ground truth to evaluate a method of analyzing IHC stained tissues.

Abstract: Disclosed herein are high Tm RNA nanostructures that can be composed of one or more modules or motifs to build RNA nanostructures with or without layers. The RNA nanostructures can have a core domain and three or more double-stranded arms and formulations thereof to conjugate high copy numbers of therapeutics, pH responsive or enzyme cleavable drug cargo. Also described herein is a design strategy for generation of synthetic RNA oligonucleotides that can self assemble into highly thermostable RNA structures. Also described herein are uses of the RNA nanostructures described herein.

Abstract: Disclosed herein are systems and devices for use in determining a level of a trait in an agriculture or food product sample. Further disclosed is a portable spectrometer system coupled with chemometric analysis methods to determine a level of a trait in an agriculture or food product sample, the portable spectrometer system comprising: a spectrometer; a sample stage adjacent the spectrometer; a motor coupled to the sample stage; and a system housing enclosing the motor and the spectrometer; wherein rotation of the motor rotates the sample stage, and wherein the motor is controllable in response to spectroscopy requirements.

Abstract: Disclosed herein are methods and apparatus for making a determination about a cataract in an eye in ambient lighting conditions.

Abstract: Disclosed herein are methods and apparatus for making a determination about an eye comprising detecting light reflected out of an eye of a subject from a retina of the eye of the subject and making a determination about the eye of the subject based upon the reflected light, wherein the light is adjusted for color temperature when making the determination about the eye.

Abstract: A T-breaker is an all-in-one solution for dc microgrid fault protection, power flow control, and power quality improvement. A T-breaker features a modular multilevel “T” structure with integrated energy storage devices. The two horizontal arms of the T-breaker realize fault current breaking, load voltage compensation, and power flow control; and the vertical arm of the T-breaker realizes shunt compensation. The configuration provides excellent voltage scalability and relaxes the requirements on the switching signal synchronization during fault transients. The local energy storage in sub-modules eases the fault energy dissipation requirement placed on the traditionally-adopted surge arrestors. The modular multilevel structure also offers immense control flexibility for all types of targeted functions of the provided T-breaker.

Abstract: Provided herein are aptamers capable of inhibiting the activity of Von Willebrand Factor (VWF). Pharmaceutical compositions comprising these aptamers are also provided. Methods of preventing blood clot formation in a subject by administering the aptamers are provided and methods of treating a blood clot by administering a VWF-targeting agent are also provided.

Abstract: The disclosed technology relates to redox flow batteries (“RFB”), and particularly to electrolytes useful in RFBs based on 2,5-dimercapto-1,3,4-thiadiazole (“DMTD”) and derivatives thereof.

Abstract: Various implementations include a fluidic oscillator having at least one control port. The at least one control port is for introducing a control fluid into the fluidic oscillator or suctioning the fluid stream from the fluidic oscillator. The introduction of a control fluid into the fluidic oscillator or suction of the fluid stream from the fluidic oscillator alters the frequency and sweeping angle of the oscillating fluid stream as it exits the fluidic oscillator. Various other implementations include a fluidic oscillator having a first control port defined by the first portion of the outlet nozzle and a second control port defined by the second portion of the outlet nozzle. The introduction of a control fluid into the fluidic oscillator or suction of the fluid stream from the fluidic oscillator through the control ports alters the exit angle of the oscillating fluid stream as it exits the fluidic oscillator.

Abstract: Disclosed herein is a contact lens comprising a rounded, minus-carrier, lenticular-like curve over a central, upper portion of the lens that allows the contact lens to translate upwards in downgaze.