Abstract: A vaccine for use in the prophylaxis and/or treatment of a disease The present invention relates to an adenoviral vector capable of encoding a virus-like particle (VLP), said VLP displaying an inactive immune-suppressive domain (ISD). The vaccine of the invention shows an improved immune response from either of both of the response pathways initiated by CD4 T cells or CD8 T cells.
Type:
Application
Filed:
July 11, 2025
Publication date:
March 19, 2026
Applicant:
INPROTHER APS
Inventors:
Peter HOLST, Christian THIRION, Lasse NEUKIRCH
Abstract: The present invention relates to an adenoviral vector capable of encoding a virus-like particle (VLP), said VLP displaying an inactive immune-suppressive domain (ISD). The vaccine of the invention shows an improved immune response from either of both of the response pathways initiated by CD4 T cells or CD8 T cells.
Type:
Grant
Filed:
August 30, 2019
Date of Patent:
August 19, 2025
Assignee:
INPROTHER APS
Inventors:
Peter Holst, Christian Thirion, Lasse Neukirch
Abstract: A vaccine for use in the prophylaxis and/or treatment of a disease The present invention relates to an adenoviral vector capable of encoding a virus-like particle (VLP), said VLP displaying an inactive immune-suppressive domain (ISD). The vaccine of the invention shows an improved immune response from either of both of the response pathways initiated by CD4 T cells or CD8 T cells.
Type:
Application
Filed:
February 21, 2025
Publication date:
June 12, 2025
Applicant:
INPROTHER APS
Inventors:
Peter HOLST, Christian THIRION, Lasse NEUKIRCH
Abstract: The present invention relates to an adenoviral vector capable of encoding a virus-like particle (VLP), said VLP displaying an inactive immune-suppressive domain (ISD). The vaccine of the invention shows an improved immune response from either of both of the response pathways initiated by CD4 T cells or CD8 T cells.
Type:
Grant
Filed:
January 16, 2024
Date of Patent:
April 1, 2025
Assignee:
INPROTHER APS
Inventors:
Peter Holst, Christian Thirion, Lasse Neukirch
Abstract: The present invention relates to an adenoviral vector capable of encoding a virus-like particle (VLP), said VLP displaying an inactive immune-suppressive domain (ISD). The vaccine of the invention shows an improved immune response from either of both of the response pathways initiated by CD4 T cells or CD8 T cells.
Type:
Grant
Filed:
April 28, 2022
Date of Patent:
July 2, 2024
Assignee:
INPROTHER APS
Inventors:
Peter Holst, Christian Thirion, Lasse Neukirch
Abstract: The present invention relates to an adenoviral vector capable of encoding a virus-like particle (VLP), said VLP displaying an inactive immune-suppressive domain (ISD). The vaccine of the invention shows an improved immune response from either of both of the response pathways initiated by CD4 T cells or CD8 T cells.
Type:
Application
Filed:
January 16, 2024
Publication date:
May 9, 2024
Applicant:
INPROTHER APS
Inventors:
Peter HOLST, Christian THIRION, Lasse NEUKIRCH
Abstract: The present invention relates to an adenoviral vector capable of encoding a virus-like particle (VLP), said VLP displaying an inactive immune-suppressive domain (ISD). The vaccine of the invention shows an improved immune response from either of both of the response pathways initiated by CD4 T cells or CD8 T cells.
Type:
Grant
Filed:
April 28, 2022
Date of Patent:
January 30, 2024
Assignee:
INPROTHER APS
Inventors:
Peter Holst, Christian Thirion, Lasse Neukirch
Abstract: The present invention relates to an adenoviral vector capable of encoding a virus-like particle (VLP), said VLP displaying an inactive immune-suppressive domain (ISD). The vaccine of the invention shows an improved immune response from either of both of the response pathways initiated by CD4 T cells or CD8 T cells.
Type:
Application
Filed:
August 30, 2019
Publication date:
June 15, 2023
Applicant:
INPROTHER APS
Inventors:
Peter HOLST, Christian THIRION, Lasse NEUKIRCH
Abstract: The present invention relates to an adenoviral vector capable of encoding a virus-like particle (VLP), said VLP displaying an inactive immune-suppressive domain (ISD). The vaccine of the invention shows an improved immune response from either of both of the response pathways initiated by CD4 T cells or CD8 T cells.
Type:
Application
Filed:
April 28, 2022
Publication date:
December 8, 2022
Applicant:
INPROTHER APS
Inventors:
Peter HOLST, Christian THIRION, Lasse NEUKIRCH
Abstract: The present invention relates to an adenoviral vector capable of encoding a virus-like particle (VLP), said VLP displaying an inactive immune-suppressive domain (ISD). The vaccine of the invention shows an improved immune response from either of both of the response pathways initiated by CD4 T cells or CD8 T cells.
Type:
Application
Filed:
April 28, 2022
Publication date:
November 3, 2022
Applicant:
INPROTHER APS
Inventors:
Peter HOLST, Christian THIRION, Lasse NEUKIRCH
Abstract: The present invention relates to an adenoviral vector capable of encoding a virus-like particle (VLP), said VLP displaying an inactive immune-suppressive domain (ISD). The vaccine of the invention shows an improved immune response from either of both of the response pathways initiated by CD4 T cells or CD8 T cells.
Type:
Grant
Filed:
August 30, 2018
Date of Patent:
June 7, 2022
Assignee:
INPROTHER APS
Inventors:
Peter Holst, Christian Thirion, Lasse Neukirch
Abstract: The present invention relates to an adenoviral vector capable of encoding a virus-like particle (VLP), said VLP displaying an inactive immune-suppressive domain (ISD). The vaccine of the invention shows an improved immune response from either of both of the response pathways initiated by CD4 T cells or CD8 T cells.
Type:
Application
Filed:
August 30, 2018
Publication date:
October 22, 2020
Applicant:
INPROTHER APS
Inventors:
Peter HOLST, Christian THIRION, Lasse NEUKIRCH