Abstract: A subcutaneous marking apparatus for placement of an imaging marker at a predetermined site in a tissue mass comprises a handle having a front portion and a rear portion, a cannula, a stylet slidably received within the cannula, a trigger extending from the front portion of the handle and operably engaging the stylet, and an imaging marker disposed within a marker recess in a distal end of the cannula. A user can firmly grasp the marking apparatus in one hand and simultaneously actuate the trigger with a finger or a thumb of the same hand to move the stylet and thereby place the imaging marker at the predetermined site.

Abstract: The invention provides a device for percutaneously implanting an imaging marker for identifying a location within a tissue mass. The subcutaneous imaging marker comprises at least a first element and a second element, each of which have a primary imaging mode. The primary imaging mode of the first element is different from that of the second element.

Abstract: A self-contained, self-piercing, and side-expelling marking apparatus for percutaneously placing a imaging marker in a tissue mass.

Abstract: A localizing wire comprising an anchor portion that can change shape from a collapsed shape to an expanded shape and thereby anchor within a tissue mass. A localizing wire having an exterior portion that can lie flat against the tissue mass. A localizing wire that can be repositioned or withdrawn without the need for the reinsertion of an introducer.

Abstract: A self-contained, self-piercing, and side-expelling marking apparatus for percutaneously placing a imaging marker in a tissue mass.

Abstract: A core biopsy device comprises an outer cutting cannula in telescoping register with an inner spoon cannula. The outer cutting cannula is provided at a distal end with an arcuate excising blade that is biased radially inwardly to extend beyond the longitudinal axis of the cannula. The inner spoon cannula terminates at a distal end in an arcuate wall to form a biopsy sample spoon for supporting a biopsy sample thereon. The outer cutting cannula can be rotated relative to the inner spoon cannula so that the excising blade can excise the biopsy sample from the surrounding tissue. After removal of the core biopsy device from the tissue, the outer cutting cannula can be retracted away from the inner spoon cannula to reveal the biopsy sample and enable the sample to be removed from the biopsy device in a relatively undisturbed condition.

Abstract: A biopsy marking apparatus for placing a radiopaque marker at the location of a percutaneous biopsy. The biopsy marking apparatus comprises an introducer in combination with a radiopaque marker. The introducer ejects the radiopaque marker at the location of the biopsy. The introducer is configured to completely eject the radiopaque marker and prevent it from being subsequently drawn into the introducer as the introducer is removed from the biopsied tissue mass. The radiopaque marker has enhanced radiopaque characteristics and enhanced non-migration characteristics.

Abstract: An apparatus for percutaneously implanting a localization wire into a tissue mass comprises a cannula with a preloaded localization wire. An actuator is provided to effect the relative movement of the cannula and localization wire such that a distal end of the localization wire is exposed to the tissue mass. A method for implanting a localization wire includes inserting a cannula with a preloaded localization wire into a tissue mass and relatively moving the cannula and localization wire to expose a portion of the localization wire to the tissue mass.

Abstract: A delivery apparatus for the percutaneous placement of a medical device at an area of interest in a tissue mass comprises an introducer comprising a cannula having an insertion tip, an expulsion opening near the insertion tip, and a medical device within the cannula comprising an imaging element, and a guide element connected to the imaging element and having a separable portion, and wherein the cannula is inserted into the tissue mass such that the medical device can be expelled through the expulsion opening into the tissue mass, and when the cannula is withdrawn from the tissue mass, the imaging element is placed within the tissue mass at the area of interest, and at least part of the guide element extends exteriorly of the tissue mass, and when the separable portion is separated from the guide element, no part of the guide element extends exteriorly of the tissue mass.

Abstract: A localizing needle comprises a barbed localizing wire fixedly sheathed within a flexible hollow infusion tube for delivering fluids to surrounding tissue through a plurality of spaced infusion ports. Echogenic and/or radiopaque markers are provided at selected intervals along the infusion tube. A helical wire bead at a distal end of the tube anchors the wire to the tube.

Abstract: A biopsy marking apparatus for placing a radiopaque marker at the location of a percutaneous biopsy. The biopsy marking apparatus comprises an introducer in combination with a radiopaque marker. The introducer ejects the radiopaque marker at the location of the biopsy. The introducer is configured to completely eject the radiopaque marker and prevent it from being subsequently drawn into the introducer as the introducer is removed from the biopsied tissue mass. The radiopaque marker has enhanced radiopaque characteristics and enhanced non-migration characteristics.

Abstract: A biopsy marking apparatus for placing a radiopaque marker at the location of a percutaneous biopsy. The biopsy marking apparatus comprises an introducer in combination with a radiopaque marker. The introducer ejects the radiopaque marker at the location of the biopsy. The introducer is configured to completely eject the radiopaque marker and prevent it from being subsequently drawn into the introducer as the introducer is removed from the biopsied tissue mass. The radiopaque marker has enhanced radiopaque characteristics and enhanced non-migration characteristics.

Abstract: Fullerenes are selectively functionalized by adsorbing fullerene molecules on molecular sieves such as zeolites as the first step in a desired functionalizing reaction and then adding functional groups or compounds to the fullerenes within the molecular sieves. An improved reactor for fullerene material is thereby available. Selectively functionalized fullerenes formed in accordance with the invention can also serve as precursors for further selectively functionalized products.

Abstract: A terminally chlorinated normal alkane hydrocarbon is produced at high terminal selectivity, by adsorbing a normal alkane into a select zeolite and chlorinating the adsorbed alkane in the zeolite. The zeolite may be of a type having internal channels of diameter slightly larger than that of the alkane, and substantially no internal chambers, and may be selected from the pentasil family of zeolites. The chlorination reaction may be conducted under heating to enhance terminal selectivity even further, in many cases to levels approaching 100%.

Abstract: A terminally chlorinated normal alkane hydrocarbon is produced at high terminal selectivity, by adsorbing a normal alkane into a select zeolite and chlorinating the adsorbed alkane in the zeolite. The zeolite may be of a type having internal channels of diameter slightly larger than that of the alkane, and substantially no internal chambers, and may be selected from the pentasil family of zeolites. The chlorination reaction may be conducted under heating to enhance terminal selectivity even further, in many cases to levels approaching 100%.