Abstract: The invention is related to compound which comprises at least one radical C?Y, Y being O or S, and an oxidable and non protonable nitrogen atom N wherein the distance (d) between the at least one carbon atom of the radical group C?Y and the nitrogen atom, when oxidized, is comprised between 0.3 and 0.8 nanometers. The invention is related to new heterocyclic compounds defined by formula G, their preparation, to pharmaceutical compositions comprising them and to their use as therapeutic agents, particularly in the treatment of neurodegenerative or Alzheimer disease.
Type:
Grant
Filed:
March 29, 2006
Date of Patent:
July 12, 2011
Assignees:
Insa Rouen, Gous Inc.
Inventors:
Francis Marsais, Pierre Bohn, Vincent Levacher, Nicolas Le Fur
Abstract: The invention is related to compound which comprises at least one radical C?Y, Y being O or S, and an oxidable and non protonable nitrogen atom N wherein the distance (d) between the at least one carbon atom of the radical group C?Y and the nitrogen atom, when oxidized, is comprised between 0.3 and 0.8 nanometers. The invention is related to new heterocyclic compounds defined by formula G, their preparation, to pharmaceutical compositions comprising them and to their use as therapeutic agents, particularly in the treatment of neurodegenerative or Alzheimer disease.
Type:
Application
Filed:
March 29, 2006
Publication date:
March 5, 2009
Applicants:
INSA ROUEN, GOUS INC.
Inventors:
Francis Marsais, Pierre Bohn, Nicolas Le Fur, Vincent Levacher