Patents Assigned to INSERM (Institut National de al Santé et de la Recherche Médicale)
  • Synthetic single domain antibody
    Patent number: 11014977
    Abstract: The invention relates to the identification of a highly stable single domain antibody scaffold (hs2dAb) and its use in generating synthetic single domain antibody library (hs2dAb-L1). The invention also relates to antigen-binding proteins comprising said stable single domain antibody scaffold and their uses, in particular as therapeutics.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: May 25, 2021
    Assignees: INSERM (Institut National de al Santé et de la Recherche Médicale), Institut Curie, Université Paus Sabatier Toulouse III, Centre National de la Recherche Scientifique (CNRS)
    Inventors: Aurelien Olichon, Sandrine Moutel, Franck Perez