Abstract: A method of identifying a subject having or at risk of having or developing a cardiovascular disease and/or a cardiovascular event, includes: measuring, in a sample obtained from the subject, at least two cardiovascular risk factors: a) sPLA2 activity and b) oxidized phospholipids on apolipoprotein B-100 particles (OxPL/apoB), combining the measurements, the combined value of sPLA2 activity and OxPL/apoB being indicative of having or a risk of having or developing a cardiovascular disease and/or cardiovascular event.
Type:
Application
Filed:
October 2, 2009
Publication date:
September 22, 2011
Applicants:
INSERM (INSTITUT NATIONAL DE LA SAINTE ET DE LA RECHERCHE MEDICALE), THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, UNIVERSITE PARIS DIDEROT-PARIS 7
Inventors:
Ziad Mallat, Alain TedguI, Sotirios Tsimikas, Joseph Witztum