Patents Assigned to INSERM (Institute de la Sante et de la Recherche Medicale)
  • Inhibitors of MRP4 and agents stimulating MRP4 activity for the treatment of cardiac disorders
    Patent number: 8420594
    Abstract: The invention relates to inhibitors of Multi drug Resistant Protein 4 (MRP4) for the treatment and/or the prevention of cardiac disorders, such as acute or chronic heart failure and cardiogenic shock. The invention also relates to agents stimulating MRP4 activity for the treatment and/or the prevention of cardiac hypertrophy.
    Type: Grant
    Filed: July 17, 2009
    Date of Patent: April 16, 2013
    Assignee: INSERM (Institute de la Sante et de la Recherche Medicale)
    Inventors: Jean-Sebastien Hulot, Anne-Marie Lompre, Yassine Sassi