Abstract: The invention relates to an ex vivo method for expanding monocytes, macrophages or dendritic cells, which method comprises inhibiting the expression or the activity of MafB and c-Maf in monocytes, macrophages or dendritic cells; and expanding the cells in the presence of at least one cytokine or an agonist of cytokine receptor signaling.
Type:
Application
Filed:
January 26, 2012
Publication date:
May 17, 2012
Applicant:
INSERM (Institute National de la Sante et de Recherche Medicale)