Patents Assigned to Inserm-Transfert
  • Motuporamine derivatives as antimicrobial agents and antibiotic enhancers against resistant gram-negative bacteria
    Patent number: 11820726
    Abstract: Motuporamine agents having antimicrobial activity and uses thereof.
    Type: Grant
    Filed: July 13, 2020
    Date of Patent: November 21, 2023
    Assignees: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC., INSERM TRANSFERT, S.A.
    Inventors: Otto Phanstiel, IV, Jean-Michel Brunel
  • Motuporamine derivatives as antimicrobial agents and antibiotic enhancers against resistant gram-negative bacteria
    Patent number: 10710957
    Abstract: Motuporamine agents having antimicrobial activity and uses thereof.
    Type: Grant
    Filed: January 9, 2018
    Date of Patent: July 14, 2020
    Assignees: University of Central Florida Research Foundation, Inc., Inserm Transfert, S.A.
    Inventors: Otto Phanstiel, IV, Jean-Michel Brunel
  • Nanocapsules with a liquid lipid core charged with water-soluble or water-dispersible active agents
    Patent number: 9333180
    Abstract: The invention relates to nanocapsules with a liquid lipidic core and a solid lipidic shell, the lipidic core being loaded with at least one water-soluble or water-dispersible ingredient, said ingredient being present in the form of a reverse micellar system.
    Type: Grant
    Filed: June 11, 2008
    Date of Patent: May 10, 2016
    Assignees: UNIVERSITE D'ANGERS, INSERM TRANSFERT
    Inventors: Patrick Saulnier, Jean-Pierre Benoit, Nicolas Anton
  • Process for preparing lipid nanoparticles
    Patent number: 9005666
    Abstract: A process for preparing nanocapsules with a liquid lipid core and a solid lipid shell, charged with at least one active agent. The process contains at least the steps of formulating a microemulsion by phase inversion of an emulsion, totally or partially forming from at least one active agent a second composition different than the microemulsion, placing the microemulsion in contact with the second composition under conditions suitable for interaction of the active agent with the microemulsion, and chill-hardening the microemulsion that has interacted with the active agent, to obtain the nanocapsules.
    Type: Grant
    Filed: June 11, 2008
    Date of Patent: April 14, 2015
    Assignees: L'Universite d'Angers, Inserm Transfert
    Inventors: Patrick Saulnier, Jean-Pierre Benoit, Nicolas Anton
  • Verotoxin B subunit for immunization
    Patent number: 8367071
    Abstract: Methods for stimulating an immune response in a mammal by administering a toxin-antigen conjugate are provided. Pharmaceutical compositions and methods for treating an antigen-related state are also described.
    Type: Grant
    Filed: February 13, 2003
    Date of Patent: February 5, 2013
    Assignees: Inserm-Transfert, Universite Pierre et Marie Curie (UPMC)
    Inventor: Allan M. Green