Abstract: Various approaches for enhancing treatment of target tissue using a source of focused ultrasound while limiting damage to non-target tissue include selecting a frequency of ultrasound waves transmitted from the source of focused ultrasound for generating a focus in the target tissue; providing microbubbles having the first size distribution such that at least 50% of the microbubbles have a radius smaller than a critical radius corresponding to a resonance frequency matching the selected frequency of ultrasound waves; and applying the ultrasound waves at the selected frequency to treat the target tissue.
Type:
Grant
Filed:
June 29, 2018
Date of Patent:
June 14, 2022
Assignee:
INSIGHTEN, LTD.
Inventors:
Rafi De Picciotto, Javier Grinfeld, Yoav Levy