Abstract: The present invention relates to a method for treating patients having Huntington's disease by a drug increasing the phosphorylation of huntingtin at position S421, thereby decreasing the polyQ-huntingtin-induced toxicity.
Type:
Application
Filed:
January 18, 2007
Publication date:
December 4, 2008
Applicants:
Insitut Curie, Centre National De La Recherche Scientifique
Abstract: 3-(amino- or aminoalkyl) pyridinone derivatives having the formula (1)
wherein Q, X, Y, and R3-R6 are as defined, which derivatives are useful for the treatment of HIV related diseases.
Type:
Grant
Filed:
July 15, 2002
Date of Patent:
January 27, 2004
Assignees:
Centre National de la Recherche Scientifique, Insitut Curie
Inventors:
Emile Bisagni, Valerie Dolle, Chi Hung Nguyen, Claude Monneret, David Grierson, Anne-Marie Aubertin