Abstract: The present invention relates generally to the use of Insulin like Growth Factor Binding Protein-3 (IGFBP-3) as an anti-neoplastic agent. More particularly, the invention relates to the use of IGFBP-3 in the treatment of patients with lung cancer.
Abstract: New pharmaceutical formulations for IGF/IGFBP complex are disclosed. IGF/IGFBP complex, preferably rhIGF-I/IGFBP-3 complex is formulated with bulking agents and optionally buffer salts, but without added osmolyte salts. Also disclosed are lyophilized formulations for IGF/IGFBP complex.
Type:
Application
Filed:
August 20, 2002
Publication date:
May 8, 2003
Applicant:
Insmed Inc.
Inventors:
Stephen Danko, David Passmore, Yasushi Ogawa