Patents Assigned to Inspirion Delivery Technologies, LLC
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Publication number: 20140275149Abstract: Orally administrable pharmaceutical compositions, methods of administration, and methods of making the same are provided. The pharmaceutical compositions provide abuse deterrent properties.Type: ApplicationFiled: March 18, 2014Publication date: September 18, 2014Applicant: Inspirion Delivery Technologies, LLCInventors: Manish S. Shah, Ray J. DiFalco, Stefan Aigner
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Publication number: 20140275150Abstract: Orally administrable pharmaceutical compositions, methods of administration, and methods of making the same are provided. The pharmaceutical compositions provide abuse deterrent properties.Type: ApplicationFiled: March 18, 2014Publication date: September 18, 2014Applicant: Inspirion Delivery Technologies, LLCInventors: Manish S. Shah, Ray J. DiFalco, Stefan Aigner
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Publication number: 20140271898Abstract: Orally administrable pharmaceutical compositions, methods of administration, and methods of making the same are provided. The pharmaceutical compositions provide abuse deterrent properties.Type: ApplicationFiled: March 18, 2014Publication date: September 18, 2014Applicant: Inspirion Delivery Technologies, LLCInventors: Manish S. Shah, Ray J. DiFalco, Stefan Aigner
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Publication number: 20140275038Abstract: Orally administrable pharmaceutical compositions, methods of administration, and methods of making the same are provided. The pharmaceutical compositions provide abuse deterrent properties.Type: ApplicationFiled: March 18, 2014Publication date: September 18, 2014Applicant: Inspirion Delivery Technologies, LLCInventors: Manish S. Shah, Ray J. DiFalco, Stefan Aigner
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Publication number: 20140275039Abstract: Orally administrable pharmaceutical compositions, methods of administration, and methods of making the same are provided. The pharmaceutical compositions provide abuse deterrent properties.Type: ApplicationFiled: March 18, 2014Publication date: September 18, 2014Applicant: Inspirion Delivery Technologies, LLCInventors: Manish S. Shah, Ray J. DiFalco, Stefan Aigner
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Publication number: 20140248343Abstract: An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (GI) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided.Type: ApplicationFiled: May 9, 2014Publication date: September 4, 2014Applicant: Inspirion Delivery Technologies, LLCInventors: Manish S. SHAH, Ray J. DiFalco
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Publication number: 20120156277Abstract: An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (GI) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided.Type: ApplicationFiled: February 29, 2012Publication date: June 21, 2012Applicant: INSPIRION DELIVERY TECHNOLOGIES, LLCInventors: Manish S. Shah, Ray J. Difalco
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Publication number: 20110184007Abstract: An oral pharmaceutical composition comprising a drug and one or more pharmaceutically acceptable excipients in a monolithic dosage form, wherein the dosage form is configured such that when the dosage form is divided into more than one piece and at least one of the pieces is administered to a subject the Cmax, AUC, and/or rate of drug released after administration is substantially the same or lower and the Tmax is higher than the Cmax, AUC, rate of drug released, and/or Tmax after administration of: (1) a comparable composition in intact dosage form of equal drug dosage of the administered at least one piece; (2) a bioequivalent drug composition in an intact dosage form of equal drug dosage to the administered at least one piece; and (3) a divided piece of a bioequivalent drug composition, wherein the divided piece comprises a drug dosage equal to the dosage of the administered piece of the oral composition. Methods of making the same and methods of using the same are also provided.Type: ApplicationFiled: February 12, 2009Publication date: July 28, 2011Applicant: INSPIRION DELIVERY TECHNOLOGIES, LLCInventors: Manish S. Shah, Ray J. Difalco
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Publication number: 20110159090Abstract: An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (GI) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided.Type: ApplicationFiled: March 4, 2011Publication date: June 30, 2011Applicant: INSPIRION DELIVERY TECHNOLOGIES, LLCInventors: Manish S. SHAH, Ray Difalco
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Publication number: 20110159089Abstract: An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (G1) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided.Type: ApplicationFiled: March 4, 2011Publication date: June 30, 2011Applicant: INSPIRION DELIVERY TECHNOLOGIES, LLCInventors: Manish S. SHAH, Ray Difalco
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Publication number: 20110150990Abstract: An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (GI) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided.Type: ApplicationFiled: March 4, 2011Publication date: June 23, 2011Applicant: INSPIRION DELIVERY TECHNOLOGIES, LLCInventors: Manish S. SHAH, Ray Difalco
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Publication number: 20110150969Abstract: An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (GI) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided.Type: ApplicationFiled: March 4, 2011Publication date: June 23, 2011Applicant: INSPIRION DELIVERY TECHNOLOGIES, LLCInventors: Manish S. SHAH, Ray DIFALCO
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Publication number: 20110150991Abstract: An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (GI) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided.Type: ApplicationFiled: March 4, 2011Publication date: June 23, 2011Applicant: INSPIRION DELIVERY TECHNOLOGIES, LLCInventors: Manish S. SHAH, Ray Difalco
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Publication number: 20110150970Abstract: An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (GI) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided.Type: ApplicationFiled: March 4, 2011Publication date: June 23, 2011Applicant: INSPIRION DELIVERY TECHNOLOGIES, LLCInventors: Manish S. Shah, Ray Difalco
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Publication number: 20110150971Abstract: An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (GI) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided.Type: ApplicationFiled: March 4, 2011Publication date: June 23, 2011Applicant: INSPIRION DELIVERY TECHNOLOGIES, LLCInventors: Manish S. SHAH, Ray DIFALCO
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Patent number: 7955619Abstract: An abuse resistant oral pharmaceutical composition, comprising: a barrier layer, comprising a first polymer; a diffusion layer, comprising a second polymer, substantially covering the barrier layer, wherein the diffusion layer is bonded to the barrier layer and comprises a drug that is substantially homogeneously distributed within the second polymer and diffuses from the diffusion layer within the gastrointestinal (GI) tract; and optionally an expansion layer comprising an expandable polymer, wherein the expansion layer is substantially covered by the barrier layer. Methods of making the same and methods of using the same are also provided.Type: GrantFiled: November 19, 2010Date of Patent: June 7, 2011Assignee: Inspirion Delivery Technologies, LLCInventors: Manish S. Shah, Ray J. Difalco