Abstract: The invention relates to factor X analogues containing the thrombin-cleavable sequence Pro-Arg-Ala in place of the-sequence Thr-Arg-Ile of the activation site of native factor X. These factor X analogues can be used to obtain procoagulant medicinal products.
Type:
Application
Filed:
June 30, 2003
Publication date:
July 6, 2006
Applicant:
INST. NAT'L DE LA SANTE ET DE LA RECH. MEDICALE
Inventors:
Virginie Louvain, Elsa Bianchini, Pierre-Emmanuel Marque, Claire Calmel-Tareau, Martine Aiach, Bernard Le Bonniec