Patents Assigned to Instil Bio, Inc.
  • Receptors providing targeted costimulation for adoptive cell therapy
    Patent number: 11945876
    Abstract: Some embodiments provided herein are chimeric costimulatory antigen receptor (CoStAR), useful in adoptive cell therapy (ACT), and cells comprising the CoStAR. In some embodiments, the CoStAR can act as a modulator of cellular activity enhancing responses to defined antigens. In some embodiments, CoStAR and/or fusion proteins, nucleic acids encoding the CoStAR and therapeutic uses thereof are also provided.
    Type: Grant
    Filed: June 15, 2022
    Date of Patent: April 2, 2024
    Assignees: Instil Bio (UK) Limited, Instil Bio, Inc.
    Inventors: John Bridgeman, Robert Hawkins, Ruben Rodriguez, Gray Kueberuwa, Milena Kalaitsidou