Patents Assigned to Institut D'Investigacions Biomediques August PI | Sunyer (IDIBAPS)
  • Methods for differentiating cells into hepatic stellate cells
    Patent number: 11492596
    Abstract: The invention is directed to methods for culturing cells so that the cells are induced to differentiate into cells that express a hepatic stellate phenotype. The invention is also directed to cells produced by the methods of the invention. The cells are useful, among other applications, for treatment of liver deficiencies, liver metabolism studies, and liver toxicity studies, fibrogenic studies, or to support hepatocyte function in co-culture setting.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: November 8, 2022
    Assignees: Katholieke Universiteit Leuven, Institut D'Investigacions Biomediques August PI | Sunyer (IDIBAPS)
    Inventors: Catherine Verfaillie, Ruben Boon, Pau Sancho Bru, Mar Col Loperena, Luis Perea Sanchez