Patents Assigned to INSTITUT DE RECHERCHE POUR LE DÉVELOPPEMENT (IRD)
  • Publication number: 20120252889
    Abstract: The present invention relates to a polyketide molecule of the following formula (I): or a pharmaceutically acceptable salt thereof, where R1 is a hydrogen atom or a (C1-C7) alkyl group, as well as the method of preparation and use thereof, in particular as an anticancer agent.
    Type: Application
    Filed: October 28, 2010
    Publication date: October 4, 2012
    Applicants: PIERRE FABRE MEDICAMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS), INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (IRD)
    Inventors: Isabelle Carletti, Georges Massiot, Cécile Debitus
  • Patent number: 8187870
    Abstract: The invention relates to an expression vector of a gene coding for an antigenic protein of Leishmania promastigote, characterized in that it comprises a PSA gene insert in opposite orientation. The invention can be applied to the development of mutants under-expressing, or no longer expressing, genes coding for an antigenic protein of Leishmania promastigote, and to the therapeutic and/or vaccine-oriented uses thereof.
    Type: Grant
    Filed: February 10, 2006
    Date of Patent: May 29, 2012
    Assignee: Institut de Recherche pour le Developpement (IRD)
    Inventors: Jean-Loup Lemesre, Philippe Holzmuller, Rachel Bras-Gonçalves
  • Publication number: 20110046077
    Abstract: The present invention relates to methods for extracting and isolating glycosyl xanthone derivatives, in particular mangiferin and isomangiferin, from plants of the Rubiaceae family, especially of the Coffea genus. The invention also relates to extracts obtained using such methods, as well as compositions comprising such extracts that are useful in the cosmetic and pharmaceutical industry.
    Type: Application
    Filed: April 10, 2009
    Publication date: February 24, 2011
    Applicant: Institut De Recherche Pour Le Developpement (IRD)
    Inventors: Pascale Talamond, Laurence Mondolot, Annick Gargadennec, Alexandre De Kochiko, Serge Hamon, Alain Fruchier, Claudine Campa
  • Publication number: 20100307985
    Abstract: A process for the decontamination of an effluent containing one or more dissolved metals is provided. The process includes producing hydrogen sulphide in an aqueous medium by culturing alkaliphilic sulphate-reducing or thio-sulphate reducing bacteria in the presence of an organic compound serving as an electron donor and in the presence of a sulphurous compound serving as an electron acceptor. The effluent is contacted with the hydrogen sulphide and the dissolved metals are reduced and/or precipitated in the form of metal sulphides.
    Type: Application
    Filed: August 16, 2010
    Publication date: December 9, 2010
    Applicant: INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (IRD)
    Inventors: Bernard Marcel Noël Ollivier, Yannick Aman Baptiste Combet-Blanc, Marie-Laure Fardeau, Bruno Chardin
  • Publication number: 20100255018
    Abstract: The present invention relates to novel antigens involved in gestational malaria, and more particularly to polynucleotide and polypeptide sequences, conjugates, cloning vectors including said sequences for the preparation of immunogenic compositions and vaccines, antibodies, and to the use thereof for treating gestational malaria. The invention also relates to diagnostic methods and kits.
    Type: Application
    Filed: April 17, 2008
    Publication date: October 7, 2010
    Applicants: INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (IRD), INSTITUT PASTEUR
    Inventors: Philippe Lucien Deloron, Nicaise Georges Tuikue Ndam, Gwladys Irénée Bertin, Peter David, Emmanuel Bischoff, Caroline Stéphanie Proux, Jean-Yves Coppee Proux, Ali Salanti, Thomas Lavstsen
  • Patent number: 7799222
    Abstract: The invention relates to using alcalophilic sulphate-reducing bacteria selected from at least one species of a Desulfohalobiaceae or Desulfonatronum species family or from species whose gene encoding for ribosomal PARN 16S has a homology equal to or greater than 97% with a corresponding gene of any species of the Desulfohalobiaceae or Desulfonatronum species family for producing a hydrogen sulphide substantially soluble in an aqueous medium.
    Type: Grant
    Filed: April 27, 2006
    Date of Patent: September 21, 2010
    Assignee: Institut de Recherche pour le Developpement (IRD)
    Inventors: Bernard Marcel Noël Ollivier, Yannick Aman Baptiste Combet-Blanc, Marie-Laure Fardeau, Bruno Chardin
  • Publication number: 20090214595
    Abstract: The invention relates to an expression vector of a gene coding for an antigenic protein of Leishmania promastigote, characterised in that it comprises a PSA gene insert in opposite orientation. The invention can be applied to the development of mutants under-expressing, or no longer expressing, genes coding for an antigenic protein of Leishmania promastigote, and to the therapeutic and/or vaccine-oriented uses thereof.
    Type: Application
    Filed: February 10, 2006
    Publication date: August 27, 2009
    Applicant: INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (IRD)
    Inventors: Jean-Loup Lemesre, Philippe Holzmuller, Rachel Bras-Goncalves
  • Publication number: 20090071897
    Abstract: The invention relates to using alcalophilic sulphate-reducing bacteria selected from at least one species of a Desulfohalobiaceae or Desulfonatronum species family or from species whose gene encoding for ribosomal PARN 16S has a homology equal to or greater than 97% with a corresponding gene of any species of the Desulfohalobiaceae or Desulfonatronum species family for producing a hydrogen sulphide substantially soluble in an aqueous medium.
    Type: Application
    Filed: April 27, 2006
    Publication date: March 19, 2009
    Applicant: INSTITUT DE RECHERCHE POUR LE DEVELOPPEMENT (IRD)
    Inventors: Bernard Marcel Noel Ollivier, Yannick Aman Baptiste Combet-Blanc, Marie-Laure Fardeau, Bruno Chardin
  • Publication number: 20080206839
    Abstract: The aim of the invention is to use sulphate-reducing thermophilic archaeobacteria for carrying out a method for degrading linear or branched, saturated or unsaturated, when necessary sulphur, aromatic hydrocarbons under anaerobic conditions.
    Type: Application
    Filed: June 30, 2006
    Publication date: August 28, 2008
    Applicant: Institut de Recherche Pour le Developpement (IRD)
    Inventors: Marie-Laure Fardeau, Bernard Ollivier, Agnes Hirschler-Rea, Nadia Khelifi
  • Publication number: 20040148667
    Abstract: The invention concerns a method for identifying in Gramineae, more particularly in maize, a nucleotide sequence involved in the apomixis in apomictic plants. The method relates to identifying the genome of the Gramineae, by phenotypic analysis, genetic mapping and marking by means of transposons, of the meiotic mutations whereof the corresponding gene is shown to be orthologous to genes involved in the expression of apomixis. The invention also concerns the use of a cloned gene in the Gramineae to identify and isolate the orthologous gene sequence in apomictic plants. The invention further concerns the use or modification of the isolated sequence in apomictic forms for inducing an apomictic development in sexual plants.
    Type: Application
    Filed: September 24, 2003
    Publication date: July 29, 2004
    Applicant: Institut De Recherche Pour Le Developpement (IRD)
    Inventors: Yves Savidan, Daniel Grimanelli, Enrico Perotti, Olivier Leblanc