Abstract: The present invention relates to novel antimicrobial peptides, to pharmaceutical compositions comprising said peptides, and to the uses thereof, in particular as antimicrobial drugs, disinfectants, pesticides or preservatives. The present invention also relates to a transgenic plant expressing said novel peptides.
Type:
Grant
Filed:
March 18, 2010
Date of Patent:
December 20, 2016
Assignees:
UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6), INSTITUT DE RECHERCHE POUR LE DEVELOPMENT, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
Inventors:
Ali Ladram, Denis Sereno, Feten Abbassi, Bruno Oury, Mohamed Amiche, Pierre Nicolas
Abstract: The invention relates to the use of a gene of the Argonaute family, a transcript of said gene or the ORF of said gene in order to produce plants that are completely or partially apomictic. The invention can be used to control apomixis in cultivated species having sexual reproduction.
Type:
Grant
Filed:
October 21, 2010
Date of Patent:
January 12, 2016
Assignee:
INSTITUT DE RECHERCHE POUR LE DEVELOPMENT (IRD)
Abstract: The subject of the invention is a novel molecule, Simalikalactone E, which can be extracted from the plant Quassia amara, and also the use thereof as a medicament, in particular in the prevention and treatment of malaria.
Type:
Grant
Filed:
June 17, 2010
Date of Patent:
December 10, 2013
Assignee:
Institut de Recherche Pour le Development
Abstract: The present invention relates to a polyketide molecule of the following formula (I): or a pharmaceutically acceptable salt thereof, where R1 is a hydrogen atom or a (C1-C7) alkyl group, as well as the method of preparation and use thereof, in particular as an anticancer agent.
Type:
Grant
Filed:
October 28, 2010
Date of Patent:
October 29, 2013
Assignees:
Pierre Fabre Medicament, Centre National de la Recherche Scientifique (CNRS), Institut de Recherche pour le Development (IRD)
Inventors:
Isabelle Carletti, Georges Massiot, Cécile Debitus
Abstract: The disclosure provides novel antigens involved in gestational malaria, and more particularly to polynucleotide and polypeptide sequences, conjugates, cloning vectors including the sequences for the preparation of immunogenic compositions and vaccines, antibodies, and to their for treating gestational malaria. Diagnostic methods and kits are described.
Type:
Grant
Filed:
April 17, 2008
Date of Patent:
October 22, 2013
Assignees:
Institut de Recherche pour le Development (IRD), Institut Pasteur
Inventors:
Philippe Lucien Deloron, Nicaise George Tuikue Ndam, Gwladys Irénée Bertin, Peter David, Emmanuel Bischoff, Caroline Stéphanie Proux, Jean-Yves Coppee, Ali Salanti, Thomas Lavstsen
Abstract: Method for the microbiological production of cinnamoyl amide derivatives of amino acids, certain products that result therefrom and uses thereof, especially as antioxidants.
Type:
Grant
Filed:
June 5, 2009
Date of Patent:
July 30, 2013
Assignee:
Institut de Recherche pour le Development
Abstract: The aim of the invention is to use sulphate-reducing thermophilic archaeobacteria for carrying out a method for degrading linear or branched, saturated or unsaturated, when necessary sulphur, aromatic hydrocarbons under anaerobic conditions.
Type:
Grant
Filed:
June 30, 2006
Date of Patent:
June 4, 2013
Assignee:
Institut de Recherche pour le Development (I.R.D.)
Inventors:
Marie-Laure Fardeau, Bernard Ollivier, Agnès Hirschler-Rea, Nadia Khelifi
Abstract: The present invention relates to an antimicrobial peptide characterised in that said peptide includes the sequence SEQ ID No. 1 or the sequence SEQ ID No. 2, the sequence SEQ ID No. 2 representing a fragment of the sequence SEQ ID No. 1, for use as a drug. Advantageously according to the invention, the peptide having sequence SEQ ID No. 1 is used specifically for treating bacterial, viral and/or parasitic infections, and the peptide having sequence SEQ No. 2 is used for treating bacterial and/or viral infections.
Type:
Application
Filed:
February 3, 2011
Publication date:
December 13, 2012
Applicant:
Institut de Recherche pour le Development (IRD)
Inventors:
Marthe Dorothée Misse Brumas, Natthanej Luplertlop, Hans Yssel, Frédéric Thomas, François Renaud
Abstract: A process for the decontamination of an effluent containing one or more dissolved metals is provided. The process includes producing hydrogen sulphide in an aqueous medium by culturing alkaliphilic sulphate-reducing or thio-sulphate reducing bacteria in the presence of an organic compound serving as an electron donor and in the presence of a sulphurous compound serving as an electron acceptor. The effluent is contacted with the hydrogen sulphide and the dissolved metals are reduced and/or precipitated in the form of metal sulphides.
Type:
Grant
Filed:
August 16, 2010
Date of Patent:
January 4, 2011
Assignee:
Institut de Recherche pour le Development (IRD)
Inventors:
Bernard Marcel Noel Ollivier, Yannick Aman Baptiste Combet-Blanc, Marie-Laure Fardeau, Bruno Chardin
Abstract: Apparatus for the automatic removal of samples of water from a continuous flow, having a frame (1) comprising a horizontal platform (4) supporting a plurality of containers (32) each designed to receive, via its open upper filling orifice (33), a water sample, and a driving ring gear mounted on a water supply pipe connected to a suction pump and joined to a dispensing arm (27) that delivers to each container in turn a sample following the rotation of this arm, the appliance being characterized in that the supporting plate has a distribution disc (23) parallel to the plate and having an even number of dispensing passages (29) numbering twice as many as the containers, half of these passages each being arranged in front of an open orifice of one of these containers and separated from each other by an analogous intermediate passage of evacuation.
Type:
Application
Filed:
January 18, 2007
Publication date:
October 1, 2009
Applicant:
Institut De Recherche Pour Le Development