Patents Assigned to Institut Europeen de Biologie Cellulaiare
  • Patent number: 7785577
    Abstract: The invention relates to a peptide of formula W-DPhe-Arg-Z (I) and to a conjugate thereof of a formula A-W-DPhe-Arg-Z (II), wherein A is a radical corresponding to a monocarboxylic acid of general formula HOOC—R (III), wherein R is an linear or branched possibly substituted by a hydroxy group aliphatic C1-C24 radical which can comprise one or several unsaturations, preferably from 1 to 6 unsaturations, a lipoic acid or the reduced form thereof, a dihydrolipoic acid, N-lipoyl-lysine or a phenylbutyric acid, W is His, Ala-His, Ala-Ala-His, Nle-Ala-His, DTrp-Ala-His, Nle-Trp-His, Lys, Ala-Lys, Nle-Ala-Lys, Orn, Ala-Orn, Nle-Ala-Orn, Ala, Nle-Ala-Ala, Arg, Ala-Arg.
    Type: Grant
    Filed: May 10, 2005
    Date of Patent: August 31, 2010
    Assignees: Institut Europeen de Biologie Cellulaiare, Centre National de la Recherche Scientifique (CNRS), Universite de Montpellier I, Universite de Montpellier II
    Inventors: Michel Hocquaux, Anne-Marie Pinel, Jean Martinez, Gilles Subra