Patents Assigned to Institut Jules Bordet
  • NEW STRATEGIES FOR TREATING MELANOMA
    Publication number: 20170165240
    Abstract: The present invention relates to a p53-activating agent capable of transferring wild-type tumor protein p53 (p53) from an inactive conformation into an active conformation capable of inducing apoptosis, for use in the treatment of melanoma, wherein said p53-activating agent is administered simultaneously or sequentially with a BRAF-inhibiting agent capable of inhibiting activity of serine/threonine-protein kinase B-Raf (BRAF) comprising an activating mutation.
    Type: Application
    Filed: April 1, 2015
    Publication date: June 15, 2017
    Applicants: Université Libre de Bruxelles, Institut Jules Bordet
    Inventors: Ghanem GHANEM, Fabrice JOURNÉ, Mohammad KRAYEM, Ahmad AWADA