Patents Assigned to INSTITUT NATIONAL DE A RECHERCHE AGRONOMIQUE
  • Patent number: 10669530
    Abstract: The present invention relates to a new strain of Clostridium acetobutylicum modified to be unable to produce hydrogen and its use for the continuous production of bulk chemicals such as lactate, 1,3-propanediol, ethanol, butanol, isobutanol, 1,3-butanediol, acetate, acetone, isopropanol, 3-hydroxy-3-methylbutyrate and isobutene at high yield.
    Type: Grant
    Filed: September 18, 2015
    Date of Patent: June 2, 2020
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES, INSTITUT NATIONAL DE A RECHERCHE AGRONOMIQUE
    Inventors: Philippe Soucaille, Ngoc-Phuong-Thao Nguyen, Benjamin Percheron, Christian Croux, Isabelle Meynial-Salles
  • Patent number: 10017748
    Abstract: The present invention relates to a recombinant process for the production of truncated or mutated dextransucrases while conserving the enzymatic activity or their specificity in the synthesis of the ?-1,6 bonds. The present invention relates to nucleic acid sequences of truncated or mutated dextransucrases, vectors containing the nucleic acid sequences and host cells transformed by sequences encoding truncated or mutated dextransucrases. In another aspect, the invention concerns a method for producing, in a recombinant manner, truncated or mutated dextransucrases which conserve their enzymatic activity or which conserve their specificity in the synthesis of ?-1,6 bonds and can produce, from saccharose, dextrans with high molar mass and modified rheological properties compared with the properties of dextran obtained with the native enzyme and isomalto-oligosaccharides with a controlled molar mass and dextrans.
    Type: Grant
    Filed: June 23, 2016
    Date of Patent: July 10, 2018
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE RECHERCHE AGRONOMIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE
    Inventors: Pierre F. Monsan, Magali Remaud-Simeon, Gabrielle Potocki-Veronese, Claire Moulis
  • Publication number: 20160298091
    Abstract: The present invention relates to a recombinant process for the production of truncated or mutated dextransucrases while conserving the enzymatic activity or their specificity in the synthesis of the ?-1,6 bonds. The present invention relates to nucleic acid sequences of truncated or mutated dextransucrases, vectors containing the nucleic acid sequences and host cells transformed by sequences encoding truncated or mutated dextransucrases. In another aspect, the invention concerns a method for producing, in a recombinant manner, truncated or mutated dextransucrases which conserve their enzymatic activity or which conserve their specificity in the synthesis of ?-1,6 bonds and can produce, from saccharose, dextrans with high molar mass and modified rheological properties compared with the properties of dextran obtained with the native enzyme and isomalto-oligosaccharides with a controlled molar mass and dextrans.
    Type: Application
    Filed: June 23, 2016
    Publication date: October 13, 2016
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE RECHERCHE AGRONOMIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE
    Inventors: Pierre F. MONSAN, Magali REMAUD-SIMEON, Gabrielle POTOCKI-VERONESE, Claire MOULIS
  • Patent number: 9399765
    Abstract: The present invention relates to a recombinant process for the production of truncated or mutated dextransucrases while conserving the enzymatic activity or their specificity in the synthesis of the ?-1,6 bonds. The present invention relates to nucleic acid sequences of truncated or mutated dextransucrases, vectors containing the nucleic acid sequences and host cells transformed by sequences encoding truncated or mutated dextransucrases. In another aspect, the invention concerns a method for producing, in a recombinant manner, truncated or mutated dextransucrases which conserve their enzymatic activity or which conserve their specificity in the synthesis of ?-1,6 bonds and can produce, from saccharose, dextrans with high molar mass and modified rheological properties compared with the properties of dextran obtained with the native enzyme and isomalto-oligosaccharides with a controlled molar mass and dextrans.
    Type: Grant
    Filed: July 14, 2015
    Date of Patent: July 26, 2016
    Assignees: Centre National de la Recherche Scientifique, Institut National de Recherche Agronomique, Institut National des Sciences Appliquees de Toulouse
    Inventors: Pierre F. Monsan, Magali Remaud-Simeon, Gabrielle Potocki-Veronese, Claire Moulis
  • Publication number: 20150344853
    Abstract: The present invention relates to a recombinant process for the production of truncated or mutated dextransucrases while conserving the enzymatic activity or their specificity in the synthesis of the ?-1,6 bonds. The present invention relates to nucleic acid sequences of truncated or mutated dextransucrases, vectors containing the nucleic acid sequences and host cells transformed by sequences encoding truncated or mutated dextransucrases. In another aspect, the invention concerns a method for producing, in a recombinant manner, truncated or mutated dextransucrases which conserve their enzymatic activity or which conserve their specificity in the synthesis of ?-1,6 bonds and can produce, from saccharose, dextrans with high molar mass and modified rheological properties compared with the properties of dextran obtained with the native enzyme and isomalto-oligosaccharides with a controlled molar mass and dextrans.
    Type: Application
    Filed: July 14, 2015
    Publication date: December 3, 2015
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DE RECHERCHE AGRONOMIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE
    Inventors: Pierre F. MONSAN, Magali REMAUD-SIMEON, Gabrielle POTOCKI-VERONESE, Claire MOULIS
  • Patent number: 9109207
    Abstract: The present invention relates to a recombinant process for the production of truncated or mutated dextransucrases while conserving the enzymatic activity or their specificity in the synthesis of the ?-1,6 bonds. The present invention relates to nucleic acid sequences of truncated or mutated dextransucrases, vectors containing the nucleic acid sequences and host cells transformed by sequences encoding truncated or mutated dextransucrases. In another aspect, the invention concerns a method for producing, in a recombinant manner, truncated or mutated dextransucrases which conserve their enzymatic activity or which conserve their specificity in the synthesis of ?-1,6 bonds and can produce, from saccharose, dextrans with high molar mass and modified rheological properties compared with the properties of dextran obtained with the native enzyme and isomalto-oligosaccharides with a controlled molar mass and dextrans.
    Type: Grant
    Filed: August 2, 2012
    Date of Patent: August 18, 2015
    Assignees: Centre National de la Recherche Scientifique, Institut National de Recherche Agronomique, Institut National des Sciences Appliquees de Toulouse
    Inventors: Pierre F. Monsan, Magali Remaud-Simeon, Gabrielle Potocki-Veronese, Claire Moulis
  • Patent number: 8263380
    Abstract: The present invention relates to a recombinant process for the production of truncated or mutated dextransucrases while conserving the enzymatic activity or their specificity in the synthesis of the ?-1,6 bonds. The present invention relates to nucleic acid sequences of truncated or mutated dextransucrases, vectors containing the nucleic acid sequences and host cells transformed by sequences encoding truncated or mutated dextransucrases. In another aspect, the invention concerns a method for producing, in a recombinant manner, truncated or mutated dextransucrases which conserve their enzymatic activity or which conserve their specificity in the synthesis of ?-1,6 bonds and can produce, from saccharose, dextrans with high molar mass and modified rheological properties compared with the properties of dextran obtained with the native enzyme and isomalto-oligosaccharides with a controlled molar mass and dextrans.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: September 11, 2012
    Assignees: Centre National de la Recherche Scientifique, Institut National de Recherche Agronomique, Institut National des Sciences Appliquees de Toulouse
    Inventors: Pierre F. Monsan, Magali Remaud-Simeon, Gabrielle Potocki-Veronese, Claire Moulis
  • Patent number: 7928182
    Abstract: An organic composition including a) a glycerol polycarbonate of the formula: in which m is equal to at least 2, and has a value from 2 to 100; b) a glycerol of formula: in which n and p are each equal to at least 2, each having a value from 2 to 150; and c) a [(?-hydroxymethyl) oxyethylene (?-hydroxymethyl) ethylene carbonate)] copolymer of the formula: in which x is equal to at least 2 and has a value between 2 and 100, y is equal to at least 2 and has a value between 2 and 100 and q is equal to at least 2 and has a value between 2 and 100.
    Type: Grant
    Filed: August 10, 2005
    Date of Patent: April 19, 2011
    Assignees: Condat S.A., INRA (Institut National de Recherche Agronomique), INPT (Institut National Polytechnique de Toulouse)
    Inventors: Nguyen T. Dinh, Zéphirin Mouloungui, Philippe Marechal
  • Patent number: 7897373
    Abstract: The present invention relates to a recombinant process for the production of truncated or mutated dextransucrases while conserving the enzymatic activity or their specificity in the synthesis of the ?-1,6 bonds. The present invention relates to nucleic acid sequences of truncated or mutated dextransucrases, vectors containing the nucleic acid sequences and host cells transformed by sequences encoding truncated or mutated dextransucrases. In another aspect, the invention concerns a method for producing, in a recombinant manner, truncated or mutated dextransucrases which conserve their enzymatic activity or which conserve their specificity in the synthesis of ?-1,6 bonds and can produce, from saccharose, dextrans with high molar mass and modified rheological properties compared with the properties of dextran obtained with the native enzyme and isomalto-oligosaccharides with a controlled molar mass and dextrans.
    Type: Grant
    Filed: February 8, 2007
    Date of Patent: March 1, 2011
    Assignees: Centre National de la Recherche Scientifique, Institut National de Recherche Agronomique, Institut National des Sciences Appliquees de Toulouse
    Inventors: Pierre F. Monsan, Magali Remaud-Simeon, Gabrielle Potocki-Veronese, Claire Moulis