Abstract: A pharmaceutical composition for treating viral infections by an influenza type A virus, includes a compound capable of acting as an inhibitor of the binding of the viral RNA to the nucleoprotein of influenza type A viruses, and capable of binding to the viral-RNA-binding domain on the nucleoprotein. A pharmaceutical composition for treating viral infections by an orthomyxovirus, includes a compound capable of acting as an inhibitor of the binding of the viral RNA to the nucleoprotein of orthomyxoviruses, and capable of binding to the viral-RNA-binding domain on the nucleoprotein of the viruses. A compound acting as an inhibitor of the binding of the viral RNA to the nucleoprotein of influenza type A viruses, and binding to the viral-RNA-binding domain on the nucleoprotein of influenza type A viruses and a method for identifying such a compound having these properties are also described.

Abstract: The invention concerns intraspecific hybrids of Agaricus bisporus capable of bearing fruit at relatively high temperature and without roughing-in, and the method for obtaining them consisting in a step of cross-breeding in particular between a first and a second Agaricus bisporus, one of which at least belongs to the burnettii variety, and a step of selecting the resulting hybrids having the characteristics mentioned above. The cultivation of the resulting hybrids is easier and less expensive than the standard method of cultivating mushrooms.