Abstract: The invention provides chondrogenic differentiation media comprising chondrogenic growth factors and low-molecular-weight sulfated polysaccharide derivatives of marine native exopolysaccharides (EPS) excreted by mesophilic marine bacteria from deep-sea hydrothermal environments. The invention relates to methods for inducing chondrogenic differentiation in pluripotent or multipotent cells, to cartilage tissues obtained by such methods, and to the use of such cartilage tissues for therapeutic purposes.
Type:
Application
Filed:
March 16, 2012
Publication date:
December 19, 2013
Applicants:
Institut National de la Sante et de Ia Recherche Medicale, UNIVERSITE DE NANTES, INSTITUT FRANCAIS DE RECHERCHE POUR L'EXPLOITATION DE LA MER