Patents Assigned to Institut National De La Sante Et De La Rechereche Scientifique (Inserm)
  • IDENTIFICATION OF A JAK2 MUTATION IN POLYCYTHEMIA VERA
    Publication number: 20140249204
    Abstract: The present invention concerns the V617F variant of the protein-tyrosine kinase JAK2, said variant being responsible for Vaquez Polyglobulia. The invention also relates to a first intention diagnostic method for erythrocytosis and thrombocytosis allowing their association with myeloproliferative disorders, or to the detection of the JAK2 V617F variant in myeloproliferative disorders allowing their reclassification in a new nosological group.
    Type: Application
    Filed: January 27, 2014
    Publication date: September 4, 2014
    Applicants: Institut Gustave-Roussy, Institut National De La Sante Et De La Rechereche Scientifique (Inserm), Universite Paris-Sud, Universite De Versailles - St Quentin En Yvelines, Assistance Publique-Hopitaux De Paris
    Inventors: William Vainchenker, Valeria Ugo, James Chloe, Jean-Pierre Le Couedic, Nicole Casadevall