Abstract: The present invention provides SOCE inhibitors that are useful as therapeutic agents in a variety of applications. The present invention also relates to pharmaceutical compositions, products and kits comprising such SOCE inhibitors, and methods of using the SOCE inhibitors in the treatment of a variety of diseases.

Abstract: Silicone material obtained by a reaction between:—at least one organopolysiloxane (A) that has a molar mass of less than 70,000 g/mol, preferably less than 50,000 g/mol, and contains siloxyl units I.1 and I.2; and—at least one organic compound (B) carrying at least two carboxylic acid groups and having no unsaturation. Y a ? Z b 1 ? SiO 4 - ( a + b ) 2 ( I ? .1 ) Z c 2 ? SiO 4 - c 2 ( I ? .

Abstract: A method is provided for selecting, from at least two available modes, a mode of interaction between a user and a digital playback device. The digital playback device is capable of obtaining at least one item of information representative of a gesture performed by a user, the gesture being performed with the aid of at least one limb or of at least one part of a limb by the user. The method includes: obtaining a number of limbs or of parts of limbs used to perform the gesture; and when the number exceeds a first predetermined value, selecting a first mode of interaction from among the at least two available modes; and when the number is less than or equal to a second predetermined value, selecting a second mode of interaction from among the at least two available modes.

Abstract: The invention relates to an imaging device (E) comprising: at least one generator (1) of structured light; an emission first image guide (5, 5?) for uplinking the structured light from the generator (1) to an object to be observed; and a return second image guide (5?, 5) for downlinking the light reflected by said object to be observed to a system (2) for capturing said reflected light. Each of the two image guides (5, 5?) is able to uplink the structured light and downlink the reflected light, and the imaging device comprises an optical switch (3) configurable into three different operating modes.