Patents Assigned to Institut National des Sciences
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Publication number: 20240116876Abstract: The present invention provides SOCE inhibitors that are useful as therapeutic agents in a variety of applications. The present invention also relates to pharmaceutical compositions, products and kits comprising such SOCE inhibitors, and methods of using the SOCE inhibitors in the treatment of a variety of diseases.Type: ApplicationFiled: May 19, 2021Publication date: April 11, 2024Applicants: Institut National de la Santé et de la Recherche Médicale, Universite de Bretagne Occidentale, Ecole Nationale Superieure de Chimie de Rennes, Institut National des Sciences Appliquees de Rennes, Universite Nangui Abrogoua, Centre National de la Recherche Scientifique, Universite de Rennes 1Inventors: Jean Pierre Bazureau, Déliko Camille Dago, Lou Anna Voli, Olivier Mignen, Christophe Brigaudeau, Yves-Alain Berko
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Patent number: 11945965Abstract: Silicone material obtained by a reaction between:—at least one organopolysiloxane (A) that has a molar mass of less than 70,000 g/mol, preferably less than 50,000 g/mol, and contains siloxyl units I.1 and I.2; and—at least one organic compound (B) carrying at least two carboxylic acid groups and having no unsaturation. Y a ? Z b 1 ? SiO 4 - ( a + b ) 2 ( I ? .1 ) Z c 2 ? SiO 4 - c 2 ( I ? .Type: GrantFiled: February 27, 2019Date of Patent: April 2, 2024Assignees: ELKEM SILICONES FRANCE SAS, INSTITUT NATIONAL DES SCIENCES APPLIQUÉES LYON, UNIVERSITÉ CLAUDE BERNARD LYON 1, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE JEAN MONNET SAINT ETIENNEInventors: François Ganachaud, Daniel Portinha De Almeida, Etienne Fleury, Gabriel Duaux, Aymeric Genest, Emmanuel Pouget
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Publication number: 20240075699Abstract: A process for manufacturing by moulding an optical component includes at least the following steps: a step of providing at least one mould, during which a glass profile is provided, said glass profile including a doping according to a predetermined geometry and having a refractive index profile depending on said doping and including at least an end including at least a structuring obtained by chemically etching of said doping, said structuring forming said at least one mould, and a moulding step, during which at least a moulding material suitable for forming at least an optical component is provided and arranged in said mould in order to shape said optical component.Type: ApplicationFiled: January 25, 2022Publication date: March 7, 2024Applicants: UNIVERSITE DE STRASBOURG, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES, UNIVERSITE FERHAT ABBAS SETIF 1Inventors: Sylvain LECLER, Nacer Eddine DEMAGH, Assia GUESSOUM, Djamila BOUAZIZ, Zaid BOUHAFS
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Patent number: 11885731Abstract: An optical particle detector including at least one channel intended to receive a fluid carrying at least one particle, and across which light rays are intended to pass such that the light rays are partially scattered by the at least one particle, a plurality of photodetectors capable of receiving said scattered light rays, wherein the detector includes at least one optical waveguide configured to collect, at least at one entrance of the waveguide, light rays that were not scattered by the at least one particle and having crossed the channel, and to reinject the unscattered light rays into the channel through at least one exit of the waveguide.Type: GrantFiled: September 21, 2021Date of Patent: January 30, 2024Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CPE LYON FORMATION CONTINUE ET RECHERCHE, ECOLE CENTRALE DE LYON, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1Inventors: Salim Boutami, Maryse Fournier, Gabriel Jobert, Christian Seassal, Cécile Jamois
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Publication number: 20240018674Abstract: The invention relates to the use of a ternary alloy having the formula SixTiyNiz, wherein x, y and z are natural numbers, for use in electrolysis and photoelectrolysis, in particular photo-oxidation of water. One aspect of the invention relates to a method for the manufacture of an electrode, the method comprising a step of heating a carrier comprising a surface having a layer of silicon on which a layer of TiO2 is disposed, the layer of TiO2 being covered with a layer of NiO; the heating step being carried out at a temperature above 1,000° C., and preferably between 1,150° C. and 1,250° C. The invention also relates to an electrode comprising a carrier, said electrode having either: an outer surface on which particles of a ternary alloy having the formula SixTiyNiz are positioned, wherein x, y and z are natural numbers, and wherein the particles form protrusions; or an outer surface consisting of a layer of said alloy, the layer comprising protrusions.Type: ApplicationFiled: November 29, 2021Publication date: January 18, 2024Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES, UNIVERSITE D'AIXMARSEILLE, UNIVERSITE DE RENNES, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNESInventors: Maxime DUFOND, Jean Manuel DECAMS, Lionel SANTINACCI, Gabriel LOGET
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Patent number: 11872071Abstract: The invention concerns a method for processing energy spectra of radiation transmitted by an object irradiated by an ionising radiation source, in particular X-ray radiation, for medical imaging or non-destructive testing applications. The method uses a detector comprising a plurality of pixels, each pixel being capable of acquiring a spectrum of the radiation transmitted by the object. The method makes it possible, based on a plurality of detected spectra, to estimate a spectrum, referred to as the scattering spectrum, representative of radiation scattered by the object. The estimation involves taking into account a spatial model of the scattering spectrum. Each acquired spectrum is corrected taking into account the estimated scattering spectrum. The invention makes it possible to reduce the influence of the scattering, by the object, of the spectrum emitted by the source.Type: GrantFiled: October 7, 2019Date of Patent: January 16, 2024Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYONInventors: Odran Pivot, Joachim Tabary, Clarisse Fournier, Jean Michel Letang, Simon Rit
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Patent number: 11875465Abstract: A virtual reality data-processing device, intended to be worn on the head of a user is disclosed. The device renders, in a field of view of the data-processing device, a virtual interaction interface, at least one part of the virtual interaction interface being rendered superimposed on a tangible device, when the tangible device is located in the field of view of the data-processing device, track at least one body part of the user likely to interact via the virtual interaction interface, detect at least one user interaction on a virtual element of the virtual interaction interface, when the at least one body part of the user is close to or in contact with the tangible device. The development also relates to a system and a method for processing virtual reality data.Type: GrantFiled: March 17, 2020Date of Patent: January 16, 2024Assignees: ORANGE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNESInventors: Guillaume Bataille, Bruno Arnaldi, Valérie Gouranton
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Publication number: 20240002832Abstract: A method for isolating molecules and/or molecular complexes having a radius of gyration smaller or equal to 2 ?m from a complex fluid, including the steps of: a) contacting a complex fluid with a structured capture array having topographical features, wherein the structured capture array is placed in an environment with surrounding humid air humidity of at least 40% based on the maximal moisture content, b) covering the deposited complex fluid with a covering element, wherein the surface tension of the complex fluid between the covering element and the structured capture array defines at least a front and a rear meniscus; and c) dragging either the covering element or the structured capture array in one direction at a speed of at most 2 mm·s?1 for displacing the complex fluid, resulting in that the molecules and/or the molecular complexes are trapped inside the cavities.Type: ApplicationFiled: December 7, 2021Publication date: January 4, 2024Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSEInventors: Aline CERF, Christophe VIEU, Hélène CAYRON, Mouhanad BABI, Denis ESTRADE, Alexiane LARROCHE
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Patent number: 11851696Abstract: The present invention relates to a recombinant microorganism which exhibits i) a conversion activity from D-ribulose-5-phosphate into D-arabinose-5-phosphate, increased in comparison with the same, non-modified microorganism; ii) a cleavage catalysis activity from D-arabinose-5-phosphate into D-glyceraldehyde-3-phosphate and glycolaldehyde, increased in comparison with the same, non-modified microorganism; iii) an oxidation activity from glycolaldehyde into glycolate, increased in comparison with the same, non-modified microorganism; and iv) an oxidation activity from glyceraldehyde-3-phosphate into 1,3-bisphosphoglycerate, decreased in comparison with the same, non-modified microorganism. The present invention also relates to a process for preparing glycolic acid from pentoses and/or hexoses, using such a recombinant microorganism.Type: GrantFiled: July 12, 2019Date of Patent: December 26, 2023Assignees: Institut National Des Sciences Appliquées De Toulouse, Centre National De La Recherche Scientifique, Institut National Recherche Pour L'Agriculture, L'Alimentation Et L'EnvironementInventors: Cléa Lachaux, Thomas Walther, Jean-Marie Francois
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Patent number: 11845944Abstract: The disclosure relates to a promoter induced by fungal rust. More specifically, the promoter is induced by the pathogen Phakopsora pachyrhizi, i.e. the Asian Soybean Rust. The disclosure further provides for recombinant genes comprising the promoter and methods of producing a transgenic plant that involves introducing or providing the recombinant gene to plant cells to create transgenic plant cells, and regenerating transgenic plants from the transgenic cells.Type: GrantFiled: May 11, 2018Date of Patent: December 19, 2023Assignees: Centre National De La Recherche Scientifique, Institut National des Sciences Appliquees de Lyon, Universite Claude Bernard Lyon 1, BASF Agricultural Solutions Seed US LLCInventors: Lisa Cabre, Sophie Ducerf, Stephane Peyrard, Catherine Sirven, Bernard Pelissier
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Publication number: 20230397490Abstract: An active light-emitting layer composition including a thermally activated delayed fluorescence (TADF) molecule with TADF properties as a host material and a luminescent molecule with circularly polarized (CP) properties as a dopant. Also, a light-emitting device, such as an organic light-emitting diodes (OLED), including the active light-emitting layer made of this composition.Type: ApplicationFiled: October 29, 2021Publication date: December 7, 2023Applicants: UNIVERSITE DE RENNES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRS -, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNES, ECOLE NATIONALE SUPERIEURE DE CHIMIE DE RENNES, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVESInventors: Ludovic FAVEREAU, Jeanne CRASSOUS, Sitthichok KASEMTHAVEECHOK, Kais DHBAIBI, Grégory PIETERS, Benoît RACINE, Etienne QUESNEL
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Patent number: 11834468Abstract: The present invention provides protected tetrasaccharides, their process of preparation and their use in the synthesis of oligosaccharides, in particular fragments of O-antigens from Shigella flexneri, for example of serotype 1a, 1b, 2a, 2b, 3a, X, 4a, 4b, 5a, 5b, 7a or 7b.Type: GrantFiled: July 3, 2018Date of Patent: December 5, 2023Assignees: INSTITUT PASTEUR, INSTITUT NATIONAL DE LA RECHERCHE AGRONOMIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Laurence Mulard, Guillaume Le Heiget, Zhaohu Hu, Louis-Antoine Barel, Isabelle Andre, Claire Moulis, Magali Remaud-Simeon, Sophie Barbe, Mounir Benkoulouche, Akli Ben Imeddourene
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Publication number: 20230360912Abstract: A method for producing nanostructures having a metal oxide shell, carried by a top face of a substrate whose greatest dimension is greater than or equal to 100 mm by MOCVD metalorganic chemical vapour deposition, including successive steps carried out in a reactor configured for MOCVD deposition of nucleation and growth. The nucleation step includes forming non-contiguous metal nuclei by depositing a metal by MOCVD using a metalorganic precursor on the top face of the substrate and oxidising the metal of the metal nuclei, to form oxidised nuclei and ensure stabilisation of the nuclei. The growth step includes depositing a metal by MOCVD using the metalorganic precursor, to form non-contiguous nanostructures by growth of the oxidised nanostructures, and oxidising the deposited metal of the nanostructures formed in the nucleation to form oxidised nanostructures.Type: ApplicationFiled: November 26, 2020Publication date: November 9, 2023Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE GRENOBLE ALPES, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, UNIVERSITE CLAUDE BERNARD LYON 1, ECOLE CENTRALE DE LYON, ECOLE SUPERIEURE CHIMIE PHYSIQUE ELECTRONIQUE LYONInventors: Pierre-Vincent GUENERY, Thierry BARON, Jeremy MOEYAERT
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Patent number: 11808646Abstract: Sensors that include carbon nanotubes, and articles that include the sensors. The sensors may include a buckypaper. The sensors may be flexible. Methods of making sensors, which may include printing an electrode on a substrate. The printing of an electrode may be achieved with an inkjet printer.Type: GrantFiled: May 29, 2019Date of Patent: November 7, 2023Assignees: The Florida State University Research Foundation, Inc., Institut National Des Sciences Appliquees De LyonInventors: Joshua H. Degraff, Pierre-Jean Cottinet, Zhiyong Liang
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Patent number: 11791129Abstract: A method for imaging a material to atomic scale by means of a field-ion microscope having a vacuum chamber configured to accommodate the material prepared in the form of a tip and an imaging gas, and an ion detector is provided. The method includes application of a DC electrical potential (VDC) and of a pulsed electrical potential, of which the maximum pulse value is denoted Vimp, so that the tip erodes for a potential value equal to VDC+Vimp; acquisition, by the detector between at least two pulses of the pulsed potential, of series of at least two ion images of the impacts of the ions repelled by the tip onto the detector; and calculation of a quantity characteristic of a trend of the erosion of the tip based on the series of ion images acquired and the adjustment, between each series of images, of the values of VDC and of Vimp such that the quantity characteristic of the trend and the ratio VDC/Vimp remain constant.Type: GrantFiled: February 20, 2020Date of Patent: October 17, 2023Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN (INSA), UNIVERSITE DE ROUEN NORMANDIEInventors: François Vurpillot, Rodrigue Larde, Benjamin Klaes, Gérald Da Costa
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Publication number: 20230295679Abstract: The present invention relates to a process for preparing an alkyl polyglucoside by enzymatic catalysis, using sucrose or an analogue thereof as substrate and making it possible to obtain a large diversity of alkyl polyglucosides in terms of size and structure of the glucoside part thereof, making possible the obtaining of an alkyl polyglucoside with a number of glucosyl units that can be adjusted from 2 to 200 glucosyl units. The process also makes it possible to adjust the linear or branched structure of the carbohydrate part of the alkyl polyglucoside obtained, and also the nature of the glycosidic bonds linking the glucose residues within the carbohydrate part.Type: ApplicationFiled: July 2, 2021Publication date: September 21, 2023Applicants: INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSE, Institut National de Recherche Pour l'Agriculture, l'Alimentation et l'Environnement, Centre National de la Recherche Scientifique (CNRS)Inventors: Etienne SEVERAC, Claire MOULIS, David GUIEYSSE, Sandrine MOREL, Magali REMAUD-SIMEON
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Publication number: 20230255105Abstract: The present invention relates to compounds simultaneously having thermally activated delayed fluorescence (TADF), circularly polarised luminescence (CPL) and aggregation-induced emission enhancement (AIEE) properties. The invention also relates to the use of such compounds as a photocatalyst or as a dopant, in particular in the emitting layers of light-emitting diodes (OLEDs), as well as light-emitting devices or light-emitting diodes (OLEDs) comprising such compounds.Type: ApplicationFiled: July 9, 2021Publication date: August 10, 2023Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITÉ PARIS-SACLAY, UNIVERSITÉ DE RENNES 1, ECOLE NATIONALE SUPÉRIEURE DE CHIMIE DE RENNES, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNESInventors: Grégory Pieters, Ludovic Favereau, Laurelie Poulard, Max Coehlo, Lucas Frederic, Sitthichok Kasemthaveechok, Jeanne Crassous
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Patent number: 11685964Abstract: Disclosed is a method and a device for retrieving, from an object A, elements G present in a matrix M, the method including at least the following steps: bringing said abject A into contact with a dense fluid Fd with a molar mass greater than 2 g mol?1 under temperature T1 and pressure P1 conditions suitable for transforming the intergranular phase and for releasing the elements G, modifying the temperature T2 and/or pressure P2 values to stop the reaction transforming the intergranular phase, and recovering the elements G separated front the matrix M.Type: GrantFiled: July 17, 2017Date of Patent: June 27, 2023Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE DE ROUEN NORMANDIE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE ROUEN NORMANDIEInventors: Jean-Marie Le Breton, Nicolas Maat, Cyril Aymonier
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Patent number: 11680586Abstract: A Venturi type ejector having a feed duct for feeding fluid under pressure with the duct extending along a central axis. A first expansion chamber is connected to the feed duct; a first mixing chamber is connected to the expansion chamber; a first suction chamber is connected to the mixing chamber; and an exhaust chamber is connected to the first mixing chamber. The ejector where the fluid under pressure penetrates into the first expansion chamber along a plurality of directions extends in a plane that is substantially orthogonal to the central axis. A vacuum generator includes such an ejector.Type: GrantFiled: January 11, 2019Date of Patent: June 20, 2023Assignees: COVAL, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUSEInventors: Lucien Baldas, Stéphane Orieux, Loïc Joguet, Michel Cecchin, Pierre Milhau
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Patent number: 11637614Abstract: Some embodiments are directed to a method of transmission from at least one transmit antenna to all or some of n reception antennas including at least one transmission step suitable for transmitting a first binary information item by using the absence of focusing from the transmit antenna to any one of the n reception antennas, during a predetermined integer number k of symbol times and/or a modulation of the power transmitted by at least one transmit antenna, participating in a coding of a second binary information item. Some other embodiments are directed to a receiver-decoder suitable for reception according to the method.Type: GrantFiled: February 3, 2017Date of Patent: April 25, 2023Assignee: INSTITUT NATIONAL DES SCIENCES APPLIQUÉES DE RENNES (INSA de RENNES)Inventors: Ali Mokh, Maryline Helard, Yvan Kokar, Matthieu Crussiere, Jean-Christophe Prevotet