Patents Assigned to Institut National des Sciences Appliquees
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Patent number: 9109207Abstract: The present invention relates to a recombinant process for the production of truncated or mutated dextransucrases while conserving the enzymatic activity or their specificity in the synthesis of the ?-1,6 bonds. The present invention relates to nucleic acid sequences of truncated or mutated dextransucrases, vectors containing the nucleic acid sequences and host cells transformed by sequences encoding truncated or mutated dextransucrases. In another aspect, the invention concerns a method for producing, in a recombinant manner, truncated or mutated dextransucrases which conserve their enzymatic activity or which conserve their specificity in the synthesis of ?-1,6 bonds and can produce, from saccharose, dextrans with high molar mass and modified rheological properties compared with the properties of dextran obtained with the native enzyme and isomalto-oligosaccharides with a controlled molar mass and dextrans.Type: GrantFiled: August 2, 2012Date of Patent: August 18, 2015Assignees: Centre National de la Recherche Scientifique, Institut National de Recherche Agronomique, Institut National des Sciences Appliquees de ToulouseInventors: Pierre F. Monsan, Magali Remaud-Simeon, Gabrielle Potocki-Veronese, Claire Moulis
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Patent number: 9082924Abstract: The present invention relates to a method for preparing, on a silicon wafer, an n+pp+ or p+nn+ structure which includes the following consecutive steps: a) on a p or n silicon wafer (1), which includes a front surface (8) and a rear surface (9), a layer of boron-doped silicon oxide (BSG) (2) is formed on the rear surface (9) by PECVD, followed by a SiOx diffusion barrier (3); b) a source of phosphorus is diffused such that the phosphorus and the boron co-diffuse and in order also to form: on the front surface (8) of the wafer obtained at the end of step a), a layer of phosphorus-doped silicon oxide (PSG) (4) and an n+ doped area (5); and on the rear surface of the wafer obtained at the end of step a), a boron-rich area (BRL) (6), as well as a p+ doped area (7); c) the layers of BSG (2) and PSG (4) oxides and SiOx (3) are removed, the BRL (6) is oxidized and the layer resulting from said oxidation is removed.Type: GrantFiled: April 26, 2011Date of Patent: July 14, 2015Assignees: EDF ENR PWT, SYNERGIES POUR EQUIPEMENTS MICRO-ELECTRONIQUE COMMUNICATION OPTIQUE SA, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Barbara Bazer-Bachi, Mustapha Lemiti, Nam Le Quang, Yvon Pellegrin
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Patent number: 9065109Abstract: The invention relates to a method for preparing a composite material comprising a polymeric matrix and a filler consisting in ion exchange inorganic particles, comprising a step for synthesis in situ of said particles within the polymeric matrix.Type: GrantFiled: June 15, 2011Date of Patent: June 23, 2015Assignees: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, INSTITUT NATIONAL DES SCIENCES APPLIQUEESInventors: Pierrick Buvat, Philippe Mazabraud, Herve Galiano, Jannick Bigarre, Veronique Bounor-Legare, Frederick Niepceron, Jean-Francois Gerard
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Patent number: 9018685Abstract: The invention relates to a structure comprising an n-type substrate (1) having a bottom surface (10) and a top surface (11), a drain (D) contacting the bottom surface (10) of the substrate (1), a first n-type semiconductor region (2) having a top surface (21) provided with a contact area (210), a source (S) contacting the contact area (210), and a second p-type semiconductor region (3) arranged inside the first semiconductor region (2) and defining first and second conduction channels (C1, C2) between the drain and the source, characterized in that said structure comprises first and second metal gratings (G1, G2), each of which has a portion (40, 71) contacting the first semiconductor region (2) so as to form a Schottky junction.Type: GrantFiled: July 13, 2011Date of Patent: April 28, 2015Assignees: Institut National des Sciences Appliquees de Lyon, Centre National de la Recherche ScientifiqueInventors: Dominique Tournier, Pierre Brosselard, Florian Chevalier
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Patent number: 9014042Abstract: The invention relates to a system for determining surroundings in a wireless network, the system including first and second nodes, each node being programmed to periodically detect the nodes located in the surroundings thereof every time period ?, characterized in that: the first node comprises a transmitter (1) and control means (3) for activating the transmitter (1) for a transmission time ? less than the time period ?, the transmitter transmitting an identification signal during the transmission time ?; the second node comprises a receiver (2) and control means (3) for activating the receiver (2) for a reception time ? less than the time period ?, the receiver (2) listening for the signals from the adjacent nodes during the reception time a, the control means (3) of the second node activating the receiver once per time period ?.Type: GrantFiled: October 28, 2011Date of Patent: April 21, 2015Assignees: Institut National des Sciences Appliquees de Lyon, Institut National de Recherche en Informatique et en Automatique, Ecole Normale Superieure de Lyon, Universite Claude Bernard Lyon I, Centre National de la Recherche Scientifique (CNRS)Inventors: Antoine Fraboulet, Eric Fleury, Guillaume Chelius
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Publication number: 20150069850Abstract: This invention relates to an electronic system including a radiative electromagnetic emitter for emitting an activation signal including sequentially an energy supply signal followed by an identification signal, the power of the energy supply signal being at least ten times greater than the power of the identification signal, further including an interface connected to an energy supply source; an electric load; a circuit for deactivating a placing of electric load on standby, including: a receiver including a reception interface, a rectifier configured to generate a DC activation voltage on the basis of an activation signal, a switch configured to selectively connect/disconnect to the load from the energy supply, an identification circuit configured to extract an identifier of the activation signal and configured to apply the activation voltage as closure control signal for turning off the switch if a match of the identifier is determined.Type: ApplicationFiled: March 7, 2013Publication date: March 12, 2015Applicants: Ecole Centrale de Lyon, Université Lyon 1 Claude Bernard, Centre National De La Recherch Scientifique, University De Limoges, Institut National Des Sciences Appliquees De LyonInventors: Christian Vollaire, Marc Thevenot, Vlad Marian, Cyrille Menudier
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Publication number: 20140338795Abstract: The invention relates to a method for manufacturing a titanium alloy having superelastic properties and/or shape memory for biomedical use, which comprises the steps of: preparing an ingot by melting the various metals that form the desired alloy in a vacuum; optionally homogenizing the ingot in a vacuum by high-temperature annealing (higher than 900° C.); first quenching; mechanical shaping (rolling, drawing, machining or the like); heat treatment for redissolution in beta phase beyond the beta transus temperature (until a second temperature and then maintaining same for a certain time); and second quenching; characterized in that said heat treatment phase is carried out in a gaseous atmosphere and also constitutes a surface treatment suitable for forming on the surface a layer of nitride, carbonitride, oxide, oxynitride or the like.Type: ApplicationFiled: November 7, 2012Publication date: November 20, 2014Applicant: INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE RENNESInventors: Thierry Gloriant, Doina Gordin
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Patent number: 8871479Abstract: The invention relates to applications of the cellulase Cel5H of Saccharophagus degradans and its homologues, functional fragments and/or variants and engineered forms thereof, in the context of recombinant, more particularly solventogenic microorganisms, more particularly C. acetobutylicum. The invention also characterizes a novel domain of the Cel5H cellulase with a putative cellulose-binding module function, and its uses in chimeric proteins for depolymerization of cellulose containing substrates.Type: GrantFiled: November 26, 2009Date of Patent: October 28, 2014Assignees: Total Marketing Services, Le Centre National de Recherche Scientifiques (CNRS), L'Institut National des Sciences Appliquees (INSA), Universite d'Aix-MarseilleInventors: Henri-Pierre Fierobe, Angélique Chanal-Vial, Anne-Laure Molinier, Chantal Tardif, Luc Dedieu
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Patent number: 8840627Abstract: A device for supporting and controlling the translational movement of an elongated body, the body extending along the longitudinal axis thereof in the form of a rod, such as a needle intended for a percutaneous medical procedure. The device is designed to be mounted to a support that can be controlled in terms of position and orientation, and includes: (i) a first member for gripping the body, whose movement can be controlled in the translation direction with a pre-determined maximum stroke; and (ii) a second fixed member which can guide the elongated body when the body is moved by the first mobile gripping member and which can maintain the body in position when the body is not engaged with the first member.Type: GrantFiled: February 28, 2006Date of Patent: September 23, 2014Assignees: Institut National des Sciences Appliquees, Institut de la Recherche sur les Cancers de l'Appareil Digestif (IRCAD), Universite de Strasbourg, Centre National de la Recherche ScientifiqueInventors: Michel De Mathelin, Benjamin Maurin, Bernard Bayle, Jacques Gangloff, Olivier Piccin
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Patent number: 8807276Abstract: The invention concerns a multilayer composite material comprising at least one core (3) interposed between two external layers (1, 2), wherein: —the core (3) is a layer of thermoviscous fluid at room temperature, said thermoviscous fluid having a dynamic viscosity coefficient greater than 100 Pa·s at room temperature, —each external layer (1, 2) is in a material in the solid state at room temperature, each external layer having a surface mass of less than 8 kg/m2.Type: GrantFiled: December 16, 2010Date of Patent: August 19, 2014Assignee: Institut National des Sciences Appliquees de LyonInventors: Jean-Louis Guyader, Husnain Inayat Hussain
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Patent number: 8804861Abstract: A method and apparatus for multicarrier transmission of a signal representing a source signal. The source signal includes symbols including a set of subcarriers, transmitted simultaneously and having pilot subcarriers intended for at least one processing operation for assisting and/or improving decoding in at least one receiver, and data subcarriers, the location in time-frequency space and a reference value of the pilot subcarriers being known to the at least one receiver. The method of transmission includes: a phase of modifying, for a given symbol, the reference value of at least one subset of the pilot subcarriers, by correction data configured to correct phase and/or amplitude for each of the pilot subcarriers of the subset, so as to minimize peak-to-average power ratio, the correction data taking at least three distinct values, a transition between the values of two successive pilot subcarriers of the subset on a frequency axis being constant.Type: GrantFiled: May 4, 2010Date of Patent: August 12, 2014Assignees: Institut National des Sciences Appliquees de Rennes, Centre National de la Recherche ScientifiqueInventors: Jean-Francois Helard, Yves Louet, Irene Masinjara Mahafeno
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Patent number: 8758744Abstract: The invention relates to an isolated polypeptide with an glycosyl transferase enzymatic activity for producing dextrans with .alpha.(1.fwdarw.2) sidechains, comprising at least one region for bonding to glucan and a catalytically active region situated beyond the region bonding to glucan. The invention further relates to polynucleotides coding for said enzymes and vectors containing the same.Type: GrantFiled: June 25, 2008Date of Patent: June 24, 2014Assignee: Institut National des Sciences Appliquees (INSA)Inventors: Sophie Anne Michèle Bozonnet, Magali Martine Claude Remaud-Simeon, René—Marc Lucien Willemot, Pierre Emmanuel Frédéric Monsan
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Patent number: 8742789Abstract: An interconnected array of reconfigurable logic cells which carry out at least one logic function, externally connected to peripheral connection network equipped with switch boxes and connected to programmable input/output blocks. The logic cells are distributed in a first dimension in rows i with i=1 to d and a second dimension in columns j with j=1 to w, with d?2 and w=2 or d=2 and w?2, each logic cell including a second input, a second input, a first output and a second output, the first input of each logic cell and the first output of each logic cell being connected to the connection network, the second input and the second output of each logic cell being connected to other different column and row logic cells except for the first and last rows or columns for d>2 or w>2 respectively.Type: GrantFiled: December 14, 2010Date of Patent: June 3, 2014Assignees: Ecole Centrale de Lyon, Universite Claude Bernard, Centre National de la Recherche Scientfique, Institut National des Sciences Appliquees de LyonInventors: Ian O'Connor, Nataliya Yakimets
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Patent number: 8682442Abstract: A wound healing system comprising an array of electrodes incorporated in a device for applying an electrical signal to a wound. The electrodes are configurable to form at least one composite electrode and the electrical signal is applied to the wound via the composite electrode(s). The system preferably includes means for determining the state of the wound, the electrode composition of the composite electrode(s) depending on the determined state of the wound. Advantageously, the electrode composition of the composite electrode(s) is adjustable in response to changes in the determined state of the wound.Type: GrantFiled: January 26, 2009Date of Patent: March 25, 2014Assignees: University of Ulster, Institut National des Sciences Appliquees de LyonInventor: Eric Thomas McAdams
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Patent number: 8669378Abstract: The present invention relates to a process for the total synthesis of epicocconone analogs of formula (I): The invention also relates to novel epicocconone analogs.Type: GrantFiled: October 25, 2010Date of Patent: March 11, 2014Assignees: Universite de Rouen, Centre National de la Recherche Scientifique-CNRS, Institut National des Sciences Appliquees de Rouen, Macquarie UniversityInventors: Xavier Franck, Philippe Peixoto, Peter Helmuth Karuso
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Publication number: 20140044969Abstract: A colloidal dispersion of a metal chalcogenide material in divided state in an aqueous liquid phase selected from the group consisting of aqueous solutions and solutions including a mixture of water and at least one solvent that is miscible with water, wherein the carbon element of the material is present in a proportion of less than 2.5 wt. % as determined by elemental analysis, the concentration of the material in the colloidal dispersion is more than 40 g/l, and the colloidal dispersion has a charge potential value which is negative and the absolute value of which is higher than 20 mV.Type: ApplicationFiled: March 7, 2012Publication date: February 13, 2014Applicants: UNIVERSITE PAUL SABATIER (TOULOUSE III ), ECOLE SUPERIEURE DES BEAUX-ARTS DE LA REUNION, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE TOULOUS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE ( C.N.R.S.)Inventors: Jean-Yves Chane-Ching, Oana Zaberca, Azmach Tolesa, Andrea Balocchi
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Publication number: 20130341234Abstract: A process for manufacturing silicon-based nanoparticles by electrochemical etching of a substrate, wherein the substrate is a metallurgical-grade or upgraded metallurgical-grade silicon, the substrate including an impurity content greater than 0.01%.Type: ApplicationFiled: March 9, 2012Publication date: December 26, 2013Applicants: INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, APOLLON SOLAR, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUEInventors: Volodymyr Lysenko, Jed Kraiem, Mahdi Medjaoui
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Patent number: 8608660Abstract: A method of tracing the likely contour of an anatomical element in a sectional image of an anatomical site, the image being composed of pixels having different intensities, the method including the steps of: a) forming columns of pixels passing through the anatomical element; b) assigning each pixel a pixel score representing the probability of the pixel being situated on the contour of the anatomical element; c) constituting a matrix of pixel scores from a plurality of columns of pixels and defining numerous continuous paths of pixels, each passing through a single pixel of each column; d) assigning each continuous path a path score that is a function of the scores of the pixels constituting the continuous path; e) selecting from a set of continuous paths the path that has the best path score, that path representing the likely contour of the anatomical element.Type: GrantFiled: July 3, 2009Date of Patent: December 17, 2013Assignees: Theraclion, Centre National de la Recherche Scientifique, Institut National des Sciences Appliquees de LyonInventors: Didier Vray, Thierry Pechoux
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Publication number: 20130309781Abstract: A complex including: a support provided with at least two faces one of which is provided with a coating of an adhesive, at least one ligand, said ligand being immobilized on the adhesive surface. The ligand implemented within the framework of the present invention is chosen from among proteins, peptides, antibodies, nucleic acids, sugars or oligosaccharides, toxins, pesticides, hormones, herbicides, fungicides, neurotransmitters.Type: ApplicationFiled: January 12, 2012Publication date: November 21, 2013Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, INSTITUT NATIONAL DES SCIENCES APPLIQUEES DE LYON, UNIVERSITE CLAUDE BERNARDInventors: Benjamin Corgier, Gaelle Legoff, Celine Mandon, Loic Blum, Christophe Marquette
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Patent number: 8574538Abstract: The invention relates to a solid material with the following formula (A): (Cu+1a-u; Ag+1u; Zn+2b-v-(y/2); Cd+2v; Sn+4c-w-(y/2); 1X+4w; 2X+3y; S?2x)(A), in which the solid material: is in divided state in the form of particles having a mean equivalent diameter of 15 nm to 400 nm; has, according to X-ray diffraction analysis of the solid material, a unique crystalline structure; is suitable for forming a stable dispersion of at least one solid material with formula (A) in a liquid, referred to as dispersion liquid, made up of at least one compound with a value of ?p higher than 8 and a value of ?H higher than 5.Type: GrantFiled: September 8, 2010Date of Patent: November 5, 2013Assignees: Universite Paul Sabatier Toulouse III, Centre National de la Recherche Scientifique (C.N.R.S.), Institut National des Sciences Appliquees de Toulouse, Ecole Superieure des Beaux-Arts de la ReunionInventors: Jean-Yves Chane-Ching, Arnaud Gillorin, Xavier Marie, Pascal Dufour, Oana Zaberca