Patents Assigned to Institut Nationale de la Recherche Agronomique (INRA)
  • Leptin antagonists
    Patent number: 7307142
    Abstract: The invention relates to synthetic leptin antagonists in which at least two amino acid residues of the sequence LDFI/S of the hydrophobic binding site at positions 39-42 of a leptin polypeptide sequence are substituted with different amino acid residues such that the site becomes less hydrophobic, and fragments of said leptin antagonists.
    Type: Grant
    Filed: November 26, 2004
    Date of Patent: December 11, 2007
    Assignees: Yissum Research and Development Company of the Hebrew University of Jerusalem, Universités Paris 6 et Paris 7, Institut Nationale de la Recherche Agronomique (INRA)
    Inventors: Arieh Gertler, Isabelle Callebaut, Jean Djiane
  • Leptin antagonists
    Publication number: 20060154859
    Abstract: The invention relates to synthetic leptin antagonists in which at least two amino acid residues of the sequence LDFI/S of the hydrophobic binding site at positions 39-42 of a leptin polypeptide sequence are substituted with different amino acid residues such that the site becomes less hydrophobic, and fragments of said leptin antagonists.
    Type: Application
    Filed: November 26, 2004
    Publication date: July 13, 2006
    Applicants: Yissum Research Development Company of The Hebrew University of Jerusalem, Universites Paris 6 et Paris 7, Institut Nationale de la Recherche Agronomique (INRA)
    Inventors: Arieh Gertler, Isabelle Callebaut, Jean Djiane
  • Microbial method for producing lignin peroxidase
    Patent number: 5153121
    Abstract: Method for producing lignin-peroxydase from the fungus Phanerochaete chrysosporium. The method comprises a first step of culture wherein the phospholipids and the emulsified fatty acids are added to the culture medium; a second step during which veratrylic alcohol is added to the culture medium, the culture medium being partially renewed for the second culture step and totally renewed for the third and fourth culture steps, by varying the content of constituents in said medium. Application to the production of lignin-peroxydase with important yields.
    Type: Grant
    Filed: April 1, 1991
    Date of Patent: October 6, 1992
    Assignee: Institut Nationale de la Recherche Agronomique-Inra
    Inventors: Marcel Asther, Cecile Capdevila, Georges Corrieu