Abstract: 1,3-dioxo-1H-benz(de)isoquinoline-2(3H) butyric acid having the following ructural formula ##STR1## A pharmaceutical composition for treating diabetes mellitus complications comprises an active agent and a pharmaceutical base material, wherein the active agent is a compound selected from the group consisting of 1,3-dioxo-1H-benz(de)isoquinoline-2(3H) butyric acid, and the sodium and potassium salts thereof.
Type:
Grant
Filed:
August 19, 1985
Date of Patent:
July 1, 1986
Assignees:
Nauchno-Issledovatelsky Institut Endokrinologii I Obmena Veschestv, Nauchno-Issledovatelsky Institut Farmakologii I Toksikologii, Institut Organicheckoi Khimii
Inventors:
Andrei S. Efimov, Igor M. Melnik, Jury V. Tkachuk, Nikolai D. Tronko, Elena K. Efimova, Irina G. Obrosova, Vadim M. Gordienko, Leonid A. Kaminsky, Vasily I. Staninets, Jury L. Zborovsky, Nikolai A. Mokhort, Lora M. Kirichek