Patents Assigned to Institut Organicheskoi Khimii
  • Patent number: 4738965
    Abstract: The present invention relates to organic chemistry.The novel compound 2-oxo-4-(2'-difluoromethylthiophenyl)-5-methoxycarbonyl-6-methyl-1,2,3,4-t etrahydropyrimidine has the formula: ##STR1## Said compound displays coronary-dilating activity and can be utilized in medicine.
    Type: Grant
    Filed: February 3, 1987
    Date of Patent: April 19, 1988
    Assignees: Institut Organischskogo Sinteza Akademii Nauk SSR, Institut Organicheskoi Khimii Akademii Nauk Ukrainskoi SSR
    Inventors: Valeria V. Kastron, Rasma O. Vitolin, Elena L. Khanina, Gunar Y. Dubur, Agris A. Kimenis, Natalya V. Kondratenko, Vladimir I. Popov, Lev M. Yagupolsky, Alexandr A. Kolomeitsev
  • Patent number: 4691046
    Abstract: A novel compound, viz, butanedioic acid mono [(2-dimethylamino)ethyl ester] succinate has the following formula: ##STR1## The compound of this invention exhibits adaprogenic and stressoprotective effects.
    Type: Grant
    Filed: January 2, 1987
    Date of Patent: September 1, 1987
    Assignees: Institut Organicheskoi Khimii Ordena Lenina I Ordena Druzhby Narodov Akademii Nauk Ukrainskoi SSR, Instiut Farmakologii Akademii Meditsinskikh Nauk SSSR
    Inventors: Miron O. Lozinsky, Jury G. Bobkov, Alla F. Shinanjuk, Jury I. Gevaza, Leonid N. Markovsky, Galina A. Kuznetsova, Valentin A. Markin, Natalya N. Kleimenova, Antonina I. Tentsova, Alexandr N. Motalov, Sergei B. Seredinin, Vladimir F. Katkov, Vasily M. Vinogradov, Vladimir I. Kulinsky
  • Patent number: 4571403
    Abstract: The anginal medicated compound according to the present invention comprises the active principle 2,4,6,8-tetramethyl-2,4,6,8-tetraazobicyclo-/3,3,0/-octanedione-3,7 of the formula: ##STR1## in combination with a pharmaceutical carrier. The medicated compound according to the present invention is useful for the treatment of patients suffering from ischemic heart disease.
    Type: Grant
    Filed: December 6, 1984
    Date of Patent: February 18, 1986
    Assignee: Institut Organicheskoi Khimii Imeni N.D. Zelinskogo Akademii Nauk SSSR
    Inventors: Irina E. Zimakova, Dania A. Valimukhametova, Irina V. Zaikonnikova, Vladimir F. Bogoyavlensky, Natalya V. Kaverina, Roman A. Kamburg, Anatoly M. Karpov, Lenor I. Khmelnitsky, Oleg V. Lebedev, Lia V. Epishina, Lidia V. Lapshina, Ljudmila I. Suvorova, Nikolai V. Darinsky, Sergei S. Novikov, deceased
  • Patent number: 4557754
    Abstract: A novel compound bis-(N,N-dimethyl-N-carbodecyloxymethyl-N-ethyleneammonium)-sulphide dichloride of the formula ##STR1## A method for preparing said novel compound comprising quaternization of bis-(.beta.-dimethylaminoethyl)-sulphide with monochloroacetic acid decyl ester, molar ratio of said reagents being not more than 1:2.A chemotherapeutic antimicrobial preparation comprising said novel compound as an active principle in combination with a pharmaceutical carrier.A plant growth regulator in the form of an aqueous solution of said novel compound in a concentration of from 0.0001 to 0.1 wt. %.
    Type: Grant
    Filed: August 13, 1980
    Date of Patent: December 10, 1985
    Assignee: Institut Organicheskoi Khimii
    Inventors: Georgy A. Golik, Yaroslav P. Demchenko, Miron O. Lozinsky, Vladlen V. Malovik, Valery Y. Semeny
  • Patent number: 4550170
    Abstract: Novel compounds, viz. 6-phenyl-2,3,5,6-tetrahydroimidazo-[2,1-b]-thiazole derivatives have the following general formula: ##STR1## wherein R is CH.sub.2 COOCH.sub.3, CH.sub.2 COOC.sub.10 H.sub.21, CH.sub.2 CONH.sub.2 X is Br.The compounds possess immunomodulating, antibacterial and antiviral activity.
    Type: Grant
    Filed: January 17, 1984
    Date of Patent: October 29, 1985
    Assignees: Institut Organicheskoi Khimii Akademii Nauk Ukrainskoi SSR, Kievsky Nauchno-Issledovatelsky Institut Otolaringologii
    Inventors: Eduard V. Gjulling, Larisa A. Djugovskaya, Dmitry I. Zabolotny, Jury P. Kovtun, Nikolai I. Liptuga, Viktor I. Litus, Marina B. Sambur, Nikolai N. Romanov, Alexei I. Tolmachev, Alexandr V. Kirsanov, Viktor N. Pisanko, Oleg F. Melnikov, Evgeny I. Klochkov
  • Patent number: 4495201
    Abstract: A novel pharmaceutical composition for treating heart diseases according to he present invention comprises -4',5,9-trimethyl-2-(4'-aza-amyl)-decadi-4,8-ene acid of the formula: ##STR1## and a pharmaceutical carrier. A method of treating heart diseases using the present composition is also disclosed.
    Type: Grant
    Filed: May 26, 1982
    Date of Patent: January 22, 1985
    Assignees: Institut Organicheskoi Khimii Imeni N.D. Zelinskogo, Vsesojuzny Kardiolgichesky Anuchny Tsentr, Institut Fiologii Razvitia Imeni N.K. Koltsova Akademii Nauk SSSR
    Inventors: Ljudmila S. Bondar, Rostan A. Okunev, Lev V. Polezhaev, Sergei P. Kolchin, Ljudmila V. Cherkasova, Lilia F. Nikolaeva
  • Patent number: 4205391
    Abstract: A device for encoding and inputting to a computer alphabetic and topologically represented graphic data that describes, in particular, structural formulae of chemical compounds, comprising an encoding tablet, a changeable encoding form placed on the encoding tablet, a coordinate counter coupled to a computer communication line and to coordinate decoders which, in turn, are coupled to the encoding tablet, a pulse generator, a pulse distributor coupled to the pulse generator, to the coordinate decoders and to the coordinate counter, a code-pulse decoder coupled to the pulse generator and to the computer communication line, an electronic writing means which is a unique and sufficient facility exercising control over the operation of the device and including an amplifier coupled to a code-pulse decoder, a coordinate pickup coupled to the amplifier, a pressure sensor coupled to the pulse generator, a beginning-of-line symbol generator coupled to the computer communication line, and a changeable writing member whic
    Type: Grant
    Filed: June 9, 1978
    Date of Patent: May 27, 1980
    Assignee: Novosibirsky Institut Organicheskoi Khimii Sibirskogo Otdelenia Akademii Nauk SSR
    Inventors: Gennady P. Ulyanov, Anatoly R. Maslov
  • Patent number: 4188406
    Abstract: A polymeric binder for use in a chewing gum of an oligomer of vinylacetate with a molecular weight of 2,500 to 6,000 and a plastifying agent, viz. water, at the following proportions of the components, percent by weight:______________________________________ vinylacetate oligomer 70 to 80 water 30 to 20.
    Type: Grant
    Filed: July 10, 1978
    Date of Patent: February 12, 1980
    Assignee: Institut Organicheskoi Khimii Akademii Nauk Armyanskoi
    Inventors: Levon A. Sarkisian, Stepan G. Matsoian, Vagram G. Gabzimalian, Shaen M. Mailian, Albert P. Galstian, Vazgen K. Azarian, Zorik S. Ter-Davtian, Raya G. Gevorkian, Ogden A. Gevorkian, Korjun L. Khudoian, Lavrenty A. Ovsepian, Amalia A. Arutjunova, Foerbakh V. Mkrtchian
  • Patent number: 4124302
    Abstract: A device for photometering a substance placed in a cylindershaped cell, comprising an aperture diaphragm and an elliptical mirror successively arranged in the path of a light beam emitted by a light source. The elliptical mirror is installed coaxially to the cylindershaped cell containing the substance to be photometered. The light beam, incident on the eliptical mirror and reflected therefrom, is focused on said cell and then collected on a photoreceiver. In the path of the light beam, incident on the elliptical mirror and reflected from said mirror, is arranged a semi-transparant mirror is arranged for directing the light beam passing through said cell to the photoreceiver. The device has low sensitivity to axial displacement of the cell with respect to the optical axis thereof, and also exhibits low sensitivity to rotation of said cell about its axis.
    Type: Grant
    Filed: March 9, 1977
    Date of Patent: November 7, 1978
    Assignee: Novosibirsky Institut Organicheskoi Khimii Sibirskogo Otdelenia Akademii Nauk SSSR
    Inventor: Sergei V. Kuzmin