Patents Assigned to Institut Organicheskoi Khimii
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Patent number: 4738965Abstract: The present invention relates to organic chemistry.The novel compound 2-oxo-4-(2'-difluoromethylthiophenyl)-5-methoxycarbonyl-6-methyl-1,2,3,4-t etrahydropyrimidine has the formula: ##STR1## Said compound displays coronary-dilating activity and can be utilized in medicine.Type: GrantFiled: February 3, 1987Date of Patent: April 19, 1988Assignees: Institut Organischskogo Sinteza Akademii Nauk SSR, Institut Organicheskoi Khimii Akademii Nauk Ukrainskoi SSRInventors: Valeria V. Kastron, Rasma O. Vitolin, Elena L. Khanina, Gunar Y. Dubur, Agris A. Kimenis, Natalya V. Kondratenko, Vladimir I. Popov, Lev M. Yagupolsky, Alexandr A. Kolomeitsev
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Patent number: 4691046Abstract: A novel compound, viz, butanedioic acid mono [(2-dimethylamino)ethyl ester] succinate has the following formula: ##STR1## The compound of this invention exhibits adaprogenic and stressoprotective effects.Type: GrantFiled: January 2, 1987Date of Patent: September 1, 1987Assignees: Institut Organicheskoi Khimii Ordena Lenina I Ordena Druzhby Narodov Akademii Nauk Ukrainskoi SSR, Instiut Farmakologii Akademii Meditsinskikh Nauk SSSRInventors: Miron O. Lozinsky, Jury G. Bobkov, Alla F. Shinanjuk, Jury I. Gevaza, Leonid N. Markovsky, Galina A. Kuznetsova, Valentin A. Markin, Natalya N. Kleimenova, Antonina I. Tentsova, Alexandr N. Motalov, Sergei B. Seredinin, Vladimir F. Katkov, Vasily M. Vinogradov, Vladimir I. Kulinsky
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Patent number: 4571403Abstract: The anginal medicated compound according to the present invention comprises the active principle 2,4,6,8-tetramethyl-2,4,6,8-tetraazobicyclo-/3,3,0/-octanedione-3,7 of the formula: ##STR1## in combination with a pharmaceutical carrier. The medicated compound according to the present invention is useful for the treatment of patients suffering from ischemic heart disease.Type: GrantFiled: December 6, 1984Date of Patent: February 18, 1986Assignee: Institut Organicheskoi Khimii Imeni N.D. Zelinskogo Akademii Nauk SSSRInventors: Irina E. Zimakova, Dania A. Valimukhametova, Irina V. Zaikonnikova, Vladimir F. Bogoyavlensky, Natalya V. Kaverina, Roman A. Kamburg, Anatoly M. Karpov, Lenor I. Khmelnitsky, Oleg V. Lebedev, Lia V. Epishina, Lidia V. Lapshina, Ljudmila I. Suvorova, Nikolai V. Darinsky, Sergei S. Novikov, deceased
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Patent number: 4557754Abstract: A novel compound bis-(N,N-dimethyl-N-carbodecyloxymethyl-N-ethyleneammonium)-sulphide dichloride of the formula ##STR1## A method for preparing said novel compound comprising quaternization of bis-(.beta.-dimethylaminoethyl)-sulphide with monochloroacetic acid decyl ester, molar ratio of said reagents being not more than 1:2.A chemotherapeutic antimicrobial preparation comprising said novel compound as an active principle in combination with a pharmaceutical carrier.A plant growth regulator in the form of an aqueous solution of said novel compound in a concentration of from 0.0001 to 0.1 wt. %.Type: GrantFiled: August 13, 1980Date of Patent: December 10, 1985Assignee: Institut Organicheskoi KhimiiInventors: Georgy A. Golik, Yaroslav P. Demchenko, Miron O. Lozinsky, Vladlen V. Malovik, Valery Y. Semeny
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Patent number: 4550170Abstract: Novel compounds, viz. 6-phenyl-2,3,5,6-tetrahydroimidazo-[2,1-b]-thiazole derivatives have the following general formula: ##STR1## wherein R is CH.sub.2 COOCH.sub.3, CH.sub.2 COOC.sub.10 H.sub.21, CH.sub.2 CONH.sub.2 X is Br.The compounds possess immunomodulating, antibacterial and antiviral activity.Type: GrantFiled: January 17, 1984Date of Patent: October 29, 1985Assignees: Institut Organicheskoi Khimii Akademii Nauk Ukrainskoi SSR, Kievsky Nauchno-Issledovatelsky Institut OtolaringologiiInventors: Eduard V. Gjulling, Larisa A. Djugovskaya, Dmitry I. Zabolotny, Jury P. Kovtun, Nikolai I. Liptuga, Viktor I. Litus, Marina B. Sambur, Nikolai N. Romanov, Alexei I. Tolmachev, Alexandr V. Kirsanov, Viktor N. Pisanko, Oleg F. Melnikov, Evgeny I. Klochkov
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Patent number: 4495201Abstract: A novel pharmaceutical composition for treating heart diseases according to he present invention comprises -4',5,9-trimethyl-2-(4'-aza-amyl)-decadi-4,8-ene acid of the formula: ##STR1## and a pharmaceutical carrier. A method of treating heart diseases using the present composition is also disclosed.Type: GrantFiled: May 26, 1982Date of Patent: January 22, 1985Assignees: Institut Organicheskoi Khimii Imeni N.D. Zelinskogo, Vsesojuzny Kardiolgichesky Anuchny Tsentr, Institut Fiologii Razvitia Imeni N.K. Koltsova Akademii Nauk SSSRInventors: Ljudmila S. Bondar, Rostan A. Okunev, Lev V. Polezhaev, Sergei P. Kolchin, Ljudmila V. Cherkasova, Lilia F. Nikolaeva
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Patent number: 4205391Abstract: A device for encoding and inputting to a computer alphabetic and topologically represented graphic data that describes, in particular, structural formulae of chemical compounds, comprising an encoding tablet, a changeable encoding form placed on the encoding tablet, a coordinate counter coupled to a computer communication line and to coordinate decoders which, in turn, are coupled to the encoding tablet, a pulse generator, a pulse distributor coupled to the pulse generator, to the coordinate decoders and to the coordinate counter, a code-pulse decoder coupled to the pulse generator and to the computer communication line, an electronic writing means which is a unique and sufficient facility exercising control over the operation of the device and including an amplifier coupled to a code-pulse decoder, a coordinate pickup coupled to the amplifier, a pressure sensor coupled to the pulse generator, a beginning-of-line symbol generator coupled to the computer communication line, and a changeable writing member whicType: GrantFiled: June 9, 1978Date of Patent: May 27, 1980Assignee: Novosibirsky Institut Organicheskoi Khimii Sibirskogo Otdelenia Akademii Nauk SSRInventors: Gennady P. Ulyanov, Anatoly R. Maslov
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Patent number: 4188406Abstract: A polymeric binder for use in a chewing gum of an oligomer of vinylacetate with a molecular weight of 2,500 to 6,000 and a plastifying agent, viz. water, at the following proportions of the components, percent by weight:______________________________________ vinylacetate oligomer 70 to 80 water 30 to 20.Type: GrantFiled: July 10, 1978Date of Patent: February 12, 1980Assignee: Institut Organicheskoi Khimii Akademii Nauk ArmyanskoiInventors: Levon A. Sarkisian, Stepan G. Matsoian, Vagram G. Gabzimalian, Shaen M. Mailian, Albert P. Galstian, Vazgen K. Azarian, Zorik S. Ter-Davtian, Raya G. Gevorkian, Ogden A. Gevorkian, Korjun L. Khudoian, Lavrenty A. Ovsepian, Amalia A. Arutjunova, Foerbakh V. Mkrtchian
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Patent number: 4124302Abstract: A device for photometering a substance placed in a cylindershaped cell, comprising an aperture diaphragm and an elliptical mirror successively arranged in the path of a light beam emitted by a light source. The elliptical mirror is installed coaxially to the cylindershaped cell containing the substance to be photometered. The light beam, incident on the eliptical mirror and reflected therefrom, is focused on said cell and then collected on a photoreceiver. In the path of the light beam, incident on the elliptical mirror and reflected from said mirror, is arranged a semi-transparant mirror is arranged for directing the light beam passing through said cell to the photoreceiver. The device has low sensitivity to axial displacement of the cell with respect to the optical axis thereof, and also exhibits low sensitivity to rotation of said cell about its axis.Type: GrantFiled: March 9, 1977Date of Patent: November 7, 1978Assignee: Novosibirsky Institut Organicheskoi Khimii Sibirskogo Otdelenia Akademii Nauk SSSRInventor: Sergei V. Kuzmin