Patents Assigned to Institut Pasteur de Montevideo
  • Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
    Patent number: 12280029
    Abstract: Methods of treating acute and chronic inflammatory conditions, tissue transplant rejection, and/or organ transplant rejection comprising administering to a subject in need thereof a therapeutically effective amount of a pluripotent anti-inflammatory and metabolic modulators optionally in combination with one or more secondary therapeutic agents and pharmaceutical compositions thereof.
    Type: Grant
    Filed: June 6, 2022
    Date of Patent: April 22, 2025
    Assignees: INSTITUT PASTEUR DE MONTEVIDEO, UNIVERSIDAD DE LA REPUBLICA
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, Maria Pia Garat Nuñez, Marcelo Hill, Mercedes Segovia
  • Ionic channel modulation as a method for treating tumors through inflammasome activation
    Patent number: 12263143
    Abstract: The invention presents use of ion channel modulator to manipulate expression of the Tmem176b gene, also known as TORID (TOlerance Related and InduceD), to treat tumors.
    Type: Grant
    Filed: October 28, 2021
    Date of Patent: April 1, 2025
    Assignees: Institut Pasteur de Montevideo, University of the Republic
    Inventors: Marcelo Hill Mongabure, Sofia Russo Rossi, Mercedes Segovia Duarte, María Inés Varela Vega, Pablo Oppezzo Llorens
  • Methods of Treatment of Inflammation Related Conditions Using Pluripotent Anti-Inflammatory and Metabolic Modulators
    Publication number: 20250099411
    Abstract: A method of treating obesity, preventing weight gain, reducing the rate of weight gain, and treating adverse effects related to obesity by administering SANA to induce thermogenesis in a subject.
    Type: Application
    Filed: April 24, 2024
    Publication date: March 27, 2025
    Applicants: Institut Pasteur de Montevideo, Universidad de la República
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Gérman Adrian Galliussi López, Mária Pia Garat Nuñez
  • VERSATILE IMMUNOGENIC MODULES AND NANOPARTICLES FOR TICK VACCINES
    Publication number: 20250082724
    Abstract: The invention relates to self-assembling multimeric recombinant proteins composed of a plurality of polypeptide subunits, and a plurality of immunogens derived from the Bm86 protein of Tick, and their applications for preventing, and controlling Tick infestations in a subject. The invention also relates to methods for engineering and producing the self-assembling multimeric recombinant proteins.
    Type: Application
    Filed: September 12, 2024
    Publication date: March 13, 2025
    Applicants: Institut Pasteur de Montevideo, Universidad de la República
    Inventors: Matias Machado, Agustin Correa, Janaina Joselin Lasalvia, Maria Soledad Valledor, Oscar Correa, Laura Decia, Uruguaysito Benavides, Alejandra Navratil, Nahuel Santana
  • ELECTROPHILIC NITROALKENE BENZOIC ACID DERIVATES AS THERAPEUTIC DRUGS IN AMYOTROPHIC LATERAL SCLEROSIS (ALS) AND OTHER NEURODEGENERATIVE CONDITIONS
    Publication number: 20240390310
    Abstract: This invention relates to the use of nitroalkene derivatives for the treatment of neurodegenerative conditions in mammals in which neuroinflammation is a contributing factor, such as in amyotrophic lateral sclerosis (ALS).
    Type: Application
    Filed: December 1, 2023
    Publication date: November 28, 2024
    Applicants: INSTITUT PASTEUR DE MONTEVIDEO, UNIVERSIDAD DE LA REPÚBLICA
    Inventors: Luis Barbeito, Emiliano Trias, Sofia Ibarburu, Carlos Batthyány, Carlos Escande, Gloria Virginia López, Williams Arturo Porcal Quinta, Mariana Ingold, Lucia Colella
  • Methods of Treatment of Inflammation Related Conditions Using Pluripotent Anti-Inflammatory and Metabolic Modulators
    Publication number: 20230346728
    Abstract: A method of treating obesity, preventing weight gain, reducing the rate of weight gain, and treating adverse effects related to obesity by administering SANA to induce thermogenesis in a subject.
    Type: Application
    Filed: March 29, 2023
    Publication date: November 2, 2023
    Applicants: Institut Pasteur de Montevideo, Universidad de la República
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Gérman Adrian Galliussi López, Mária Pia Garat Nuñez
  • Methods Of Treatment Of Inflammation Related Conditions Using Pluripotent Anti-inflammatory And Metabolic Modulators
    Publication number: 20220296546
    Abstract: Methods of treating acute and chronic inflammatory conditions, tissue transplant rejection, and/or organ transplant rejection comprising administering to a subject in need thereof a therapeutically effective amount of a pluripotent anti-inflammatory and metabolic modulators optionally in combination with one or more secondary therapeutic agents and pharmaceutical compositions thereof.
    Type: Application
    Filed: June 6, 2022
    Publication date: September 22, 2022
    Applicants: INSTITUT PASTEUR DE MONTEVIDEO, UNIVERSIDAD DE LA REPÚBLICA
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, Maria Pia Garat Nuñez, Marcelo Hill, Mercedes Segovia
  • Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
    Patent number: 11400066
    Abstract: Methods of treating acute and chronic inflammatory conditions, tissue transplant rejection, and/or organ transplant rejection comprising administering to a subject in need thereof a therapeutically effective amount of a pluripotent anti-inflammatory and metabolic modulators optionally in combination with one or more secondary therapeutic agents and pharmaceutical compositions thereof.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: August 2, 2022
    Assignees: INSTITUT PASTEUR DE MONTEVIDEO, UNIVERSIDAD DE LA REPÚBLICA
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, María Pia Garat Nuñez
  • Immunoresponsive methods of treating tumors
    Patent number: 11246858
    Abstract: Within the scope of the present invention is a new pharmacological strategy for the treatment of tumors based on anti-tumoral immune responses.
    Type: Grant
    Filed: May 2, 2018
    Date of Patent: February 15, 2022
    Assignee: INSTITUT PASTEUR DE MONTEVIDEO
    Inventors: Marcelo Hill, Mercedes Segovia, Sofia Russo, Mathias Jeldres, Maria Romina Girotti, Maite Duhalde Vega, Yamil Damián Mahmoud
  • Methods of Treatment of Inflammation Related Conditions Using Pluripotent Anti-Inflammatory and Metabolic Modulators
    Publication number: 20210212972
    Abstract: A method of treating obesity, preventing weight gain, reducing the rate of weight gain, and treating adverse effects related to obesity by administering SANA to induce thermogenesis in a subject.
    Type: Application
    Filed: March 30, 2021
    Publication date: July 15, 2021
    Applicants: Institut Pasteur de Montevideo, Universidad de la República
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Gérman Adrian Galliussi López, Mária Pia Garat Nuñez
  • ELECTROPHILIC NITROALKENE BENZOIC ACID DERIVATES AS THERAPEUTIC DRUGS IN AMYOTROPHIC LATERAL SCLEROSIS (ALS) AND OTHER NEURODEGENERATIVE CONDITIONS
    Publication number: 20210121425
    Abstract: This invention relates to the use of nitroalkene derivatives for the treatment of neurodegenerative conditions in mammals in which neuroinflammation is a contributing factor, such as in amyotrophic lateral sclerosis (ALS).
    Type: Application
    Filed: October 26, 2020
    Publication date: April 29, 2021
    Applicants: Institut Pasteur de Montevideo, Universidad de la República
    Inventors: Luis Barbeito, Emiliano Trías, Sofía Ibarburu, Carlos Batthyány, Carlos Escande, Gloria Virginia López, Williams Arturo Porcal Quinta, Mariana Ingold, Lucia Colella
  • NITROALKENE NON STEROIDAL ANTI-INFLAMMATORY DRUGS (NA-NSAIDS) AND METHODS OF TREATING INFLAMMATION RELATED CONDITIONS
    Publication number: 20210107860
    Abstract: Nitroalkene non-steroidal anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of treating inflammation related conditions.
    Type: Application
    Filed: December 23, 2020
    Publication date: April 15, 2021
    Applicants: Institut Pasteur de Montevideo, Universidad de la República
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, María Pia Garat Nuñez, Paulina Invernizzi, Mariana Ingold, Lucia Colella
  • Nitroalkene non steroidal anti-inflammatory drugs (NA-NSAIDS) and methods of treating inflammation related conditions
    Patent number: 10906864
    Abstract: Nitroalkene non-steroidal anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of treating inflammation related conditions.
    Type: Grant
    Filed: August 7, 2019
    Date of Patent: February 2, 2021
    Assignees: INSTITUT PASTEUR DE MONTEVIDEO, UNIVERSIDAD DE LA REPUBLICA
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, María Pia Garat Nuñez, Paulina Invernizzi, Mariana Ingold, Lucia Colella
  • Methods of Treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic Modulators
    Publication number: 20200155486
    Abstract: A method of treating obesity, preventing weight gain, reducing the rate of weight gain, and treating adverse effects related to obesity by administering SANA to induce thermogenesis in a subject.
    Type: Application
    Filed: September 20, 2019
    Publication date: May 21, 2020
    Applicants: Institut Pasteur de Montevideo, Universidad de la República
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, María Pia Garat Nuñez
  • Methods of Treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic Modulators
    Publication number: 20200147017
    Abstract: Methods of treating acute and chronic inflammatory conditions, tissue transplant rejection, and/or organ transplant rejection comprising administering to a subject in need thereof a therapeutically effective amount of a pluripotent anti-inflammatory and metabolic modulators optionally in combination with one or more secondary therapeutic agents and pharmaceutical compositions thereof.
    Type: Application
    Filed: January 17, 2020
    Publication date: May 14, 2020
    Applicants: Institut Pasteur de Montevideo, Universidad de la República
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, María Pia Garat Nuñez, Marcelo Hill, Mercedes Segovia
  • Methods of treatment of inflammation related conditions using pluripotent anti-inflammatory and metabolic modulators
    Patent number: 10537537
    Abstract: Methods of treating acute and chronic inflammatory conditions, tissue transplant rejection, and/or organ transplant rejection comprising administering to a subject in need thereof a therapeutically effective amount of a pluripotent anti-inflammatory and metabolic modulators optionally in combination with one or more secondary therapeutic agents and pharmaceutical compositions thereof.
    Type: Grant
    Filed: October 16, 2017
    Date of Patent: January 21, 2020
    Assignees: Institut Pasteur de Montevideo, Universidad de la República
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, María Pia Garat Nuñez, Marcelo Hill, Mercedes Segovia
  • NITROALKENE NON STEROIDAL ANTI-INFLAMMATORY DRUGS (NA-NSAIDS) AND METHODS OF TREATING INFLAMMATION RELATED CONDITIONS
    Publication number: 20190359552
    Abstract: Nitroalkene non-steroidal anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of treating inflammation related conditions.
    Type: Application
    Filed: August 7, 2019
    Publication date: November 28, 2019
    Applicants: Institut Pasteur de Montevideo, Universidad de la República
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, María Pia Garat Nuñez, Paulina Invernizzi, Mariana Ingold, Lucia Colella
  • Nitroalkene non steroidal anti-inflammatory drugs (NA-NSAIDs) and methods of treating inflammation related conditions
    Patent number: 10428008
    Abstract: Nitroalkene non-steroidal anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of treating inflammation related conditions.
    Type: Grant
    Filed: December 27, 2017
    Date of Patent: October 1, 2019
    Assignee: Institut Pasteur de Montevideo
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, María Pia Garat Nuñez, Paulina Invernizzi, Mariana Ingold, Lucia Colella
  • NITROALKENE NON STEROIDAL ANTI-INFLAMMATORY DRUGS (NA-NSAIDS) AND METHODS OF TREATING INFLAMMATION RELATED CONDITIONS
    Publication number: 20190194121
    Abstract: Nitroalkene non-steroidal anti-inflammatory compounds, pharmaceutical compositions thereof, and methods of treating inflammation related conditions.
    Type: Application
    Filed: December 27, 2017
    Publication date: June 27, 2019
    Applicants: Institut Pasteur de Montevideo, Universidad de la República
    Inventors: Carlos Batthyány, Gloria Virginia López, Carlos Escande, Jorge Rodriguez Duarte, Williams Arturo Porcal Quinta, Rosina Dapueto Capuccio, Germán Adrian Galliussi López, María Pia Garat Nuñez, Paulina Invernizzi, Mariana Ingold, Lucia Colella
  • Immunoresponsive Methods of Treating Tumors
    Publication number: 20180318273
    Abstract: Within the scope of the present invention is a new pharmacological strategy for the treatment of tumors based on anti-tumoral immune responses.
    Type: Application
    Filed: May 2, 2018
    Publication date: November 8, 2018
    Applicant: Institut Pasteur de Montevideo
    Inventors: Marcelo Hill, Mercedes Segovia, Sofia Russo, Maria Cristina Cuturi, Mathias Jeldres, Maria Romina Girotti, Maite Duhalde Vega, Yamil Damián Mahmoud