Patents Assigned to INSTITUT QUIMIC DE SARRIA
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Patent number: 11944723Abstract: A vascular repair patch with a polymeric substrate having first and second major surfaces, and at least first and second polymer filament layers, wherein the polymer filaments of the first polymer filament layer are oriented in parallel and the polymer filaments of the second polymer filament layer are oriented randomly. The patch may further include thrombogenic agents and/or extracellular matrix compounds to promote vascular tissue regeneration at the repair site. Further, included are methods of making and using the patch.Type: GrantFiled: March 13, 2019Date of Patent: April 2, 2024Assignee: INSTITUT QUIMIC DE SARRIA CETS FUNDACIO PRIVADAInventors: Jordi Martorell López, Salvador Borrós Gómez, Noemí Balà Palasí, Mercedes Balcells Camps
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Patent number: 10226467Abstract: The present invention relates to a compound of formula (I), provided that this compound is not caffeine, for use in the treatment of myotonic dystrophy type 1 and type 2. The present invention also relates to compositions comprising the compound of formula (I). The present invention further relates to new compounds which are dimers of compounds of formula (I).Type: GrantFiled: November 13, 2015Date of Patent: March 12, 2019Assignees: Universitat de Valencia, Institut Quimic de Sarria Cets Fundacio Privada, Institut Univ. de Ciencia I Tecnologia, S.A.Inventors: Ruben Artero Allepuz, Josep Castells Boliart, José Ignacio Borrell Bilbao, Beatriz Llamusi Troísi, Ariadna Bargiela Schönbrunn, Piotr Konieczny, Marta Pascual Gilabert, Jordi Teixidó Closa, Roger Estrada Tejedor, Alejandro López González
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Patent number: 10004602Abstract: Bioactive implant for myocardial regeneration and ventricular chamber support including an elastomeric microporous membrane. The elastomeric microporous membrane being at least one non-degradable polymer and at least one partially degradable polymer. The non-degradable polymer is selected from polyethylacrylate and polyethylacrylate copolymerized with a hydroxyethylacrylate comonomer. The partially degradable polymer is selected from caprolactone 2-(methacryloyloxy)ethyl ester and caprolactone 2-(methacryloyloxy)ethyl ester copolymerized with ethylacrylate. The elastomeric microporous membrane further includes a nanofiber hydrogel, and cells. The bioactive implant, having one or two helical loops, contributes to the restoration of the heart conical shape.Type: GrantFiled: May 23, 2016Date of Patent: June 26, 2018Assignees: INSTITUT QUIMIC DE SARRIA, UNIVERSIDAD POLITECNICA VALENCIA, FUNDACION GERMANS TRIAS PUJOL, ASSOCIATION CARDIO-MONDEInventors: Juan Carlos Chachques, Antonio Bayes Genis, Manuel Monleon Pradas, Carlos Eduardo Semino, Philippe Jenny
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Patent number: 9938435Abstract: The present invention relates to an adhesive composition comprising a component A and a component B, wherein said component A comprises bisphenol A resin; a hydrophilic solvent, preferably acetone or ethanol or mixtures thereof; and silica gel (SiO2) or alumina (Al2O3) and said component B comprises aliphatic or aromatic polyamines, preferably polyamidoamines; polythiol; a combination of primary and tertiary amines, preferably 1-(2-aminoethyl)piperazine and ethylenediamine; optionally a hydrophilic solvent and optionally silica (SiO2) or alumina (Al2O3) gel. Said composition has the advantage that it cures, in addition to under dry conditions, in the presence of water or humidity in a time of 30 minutes as much and is flexible. The present invention also relates to a process for obtaining said adhesive composition.Type: GrantFiled: October 24, 2012Date of Patent: April 10, 2018Assignees: INSTITUT QUIMIC DE SARRIA CETS FUNDACIO PRIVADA, PJM PUJADAS, S.A.Inventors: Jorge Parellada Llobet, Jordi Arbusá Amorós, Salvador Borrós Gómez
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Patent number: 9630962Abstract: The present invention is related to 4-amino-6-(2,6-dichlorophenyl)-2-(phenylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one derivatives, to the preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in the treatment and/or prevention of a non-Hodgkin's lymphoma.Type: GrantFiled: June 16, 2014Date of Patent: April 25, 2017Assignees: HOSPITAL CLINIC DE BARCELONA, FUNDACIÓ CLINIC PER A LA RECERCA BIOMÈDICA, INSTITUT D'INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER, INSTITUT QUÍMIC DE SARRIÁ, CETS FUNDACIÓ PRIVADAInventors: José Ignacio Borrell Bilbao, Jordi Teixido Closa, Raimon Puig De La Bellacasa Cazorla, Dolors Colomer Pujol, Gael Roue, Patricia Pérez-Galán
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Patent number: 9381251Abstract: This invention relates to a thermoplastic paste with a highly thixotropic rheology, the components of which are a block biopolymer and a bioceramic. The material described herein can be used in bone implants and in the regeneration of both animal and plant live tissues.Type: GrantFiled: February 6, 2014Date of Patent: July 5, 2016Assignees: INSTITUT QUIMIC DE SARRIA CETS, FUNDACIO PRIVADA, UNIVERSITAT RAMON LLULL, FUNDACIO PRIVADAInventors: Salvador Borros Gomez, David Horna Tomas
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Publication number: 20160176866Abstract: The present invention is related to 4-amino-6-(2,6-dichlorophenyl)-2-(phenylamino)-pyrido[2,3-d]pyrimidin-7(8H)-one derivatives, to the preparation of such compounds, to pharmaceutical compositions comprising them, and to their use in the treatment and/or prevention of a non-Hodgkin's lymphoma.Type: ApplicationFiled: June 16, 2014Publication date: June 23, 2016Applicants: INSTITUT QUÍMIC DE SARRIÁ, CETS FUNDACIÓ, PRIVADA, HOSPITAL CLÍNIC DE BARCELONA, FUNDACIÓ CLINIC PER A LA RECERCA BIOMÈDICA (FCRB), INSTITUT D'INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYERInventors: José Ignacio Borrell Bilbao, Jordi Teixido Closa, Raimon Puig De La Bellacasa Cazorla, Dolors Colomer Pujol, Gael Roue, Patricia Pérez-Galán
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Patent number: 8968417Abstract: Bioactive implant for myocardial regeneration and ventricular chamber support including an elastomeric microporous membrane. The elastomeric microporous membrane being at least one non-degradable polymer and at least one partially degradable polymer. The non-degradable polymer is selected from polyethylacrylate and polyethylacrylate copolymerized with a hydroxyethylacrylate comonomer. The partially degradable polymer is selected from caprolactone 2-(methacryloyloxy)ethyl ester and caprolactone 2-(methacryloyloxy)ethyl ester copolymerized with ethylacrylate. The elastomeric microporous membrane further includes a nanofiber hydrogel, and cells. The bioactive implant, having one or two helical loops, contributes to the restauration of the heart conical shape.Type: GrantFiled: October 25, 2012Date of Patent: March 3, 2015Assignees: Institut Quimic de Sarria, Universitad Politecnica de Valencia, Fundacio Institut d'Investigacio Sanitaria Germans Trias Pujol, Association Cardio-MondeInventors: Juan Carlos Chachques, Antonio Bayes Genis, Manuel Monleon Pradas, Carlos Eduardo Semino, Nicole Zur Nieden, Philippe Jenny
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Publication number: 20140213641Abstract: Disclosed are nanoparticles comprising a block copolymer and optionally one or more active agent(s), compositions comprising said nanoparticles and methods of preparing said nanoparticles. The block copolymer comprises blocks (i) a first polymer that is a polyester or polyamide and (ii) a second polymer comprising a hydrocarbon chain containing ester or ether bonds with hydroxyl number ?10. The active agent(s) may be present within the nanoparticles or on the surfaces of the nanoparticles. The nanoparticles may optionally be associated with a surface-modifying moiety such that they are useful as drug delivery and molecular imaging devices. The surface-modifying moiety may target the nanoparticles to a desired target, cell, tissue or biomarker.Type: ApplicationFiled: May 9, 2012Publication date: July 31, 2014Applicant: INSTITUT QUIMIC DE SARRIAInventors: Salvador Borros Gomez, Primiano Pio Di Mauro
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Publication number: 20140155267Abstract: This invention relates to a thermoplastic paste with a highly thixotropic rheology, the components of which are a block biopolymer and a bioceramic. The material described herein can be used in bone implants and in the regeneration of both animal and plant live tissues.Type: ApplicationFiled: February 6, 2014Publication date: June 5, 2014Applicants: UNIVERSITAT RAMON LLULL, FUNDACIO PRIVADA, INSTITUT QUIMIC DE SARRIA CETS, FUNDACIO PRIVADAInventors: Salvador Borros Gomez, David Horna Tomas
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Patent number: 8703111Abstract: This invention relates to a thermoplastic paste with a highly thixotropic rheology, the components of which are a block biopolymer and a bioceramic. The material described herein can be used in bone implants and in the regeneration of both animal and plant live tissues.Type: GrantFiled: May 6, 2009Date of Patent: April 22, 2014Assignees: Institut Quimic de Sarria Cets, Fundacio Privada, Universitat Ramon Llull, Fundacio PrivadaInventors: Salvador Borros Gómez, David Horna Tomás
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Publication number: 20110130290Abstract: This invention relates to a thermoplastic paste with a highly thixotropic rheology, the components of which are a block biopolymer and a bioceramic. The material described herein can be used in bone implants and in the regeneration of both animal and plant live tissues.Type: ApplicationFiled: May 6, 2009Publication date: June 2, 2011Applicants: INSTITUT QUIMIC DE SARRIA CETS, FUNDACIO PRIVADA, UNIVERSITAT RAMON LLULL, FUNDACIO PRIVADAInventors: Salvador Borros Gomez, David Horna Tomas