Patents Assigned to Institut Swisse de Recherches Experimentales sur le Cancer
  • Hydroxyapatite-antigen conjugates and methods for generating a poly-Ig immune response
    Patent number: 5443832
    Abstract: A method for generating antigen-sensitized Ig-A-producing lymphoblasts in a mammal, using an immunogen comprising an antigen or antigen mixture in association with hydroxylated calcium phosphate (hydroxy apatite) is administered to a mucosal surface of the mammal.
    Type: Grant
    Filed: April 16, 1990
    Date of Patent: August 22, 1995
    Assignee: Institut Swisse de Recherches Experimentales sur le Cancer
    Inventors: Helen M. Amerongen, Marian R. Neutra, Jean-Pierre Kraehenbuhl