Abstract: The present invention relates to polypeptides and uses thereof for reducing CD95-meditated cell motility. In particular, the present invention relates to a polypeptide having an amino acid sequence having at least 70% of identity with the amino acid sequence ranging from the amino-acid residue at position 175 to the amino-acid residue at position 191 in SEQ ID NO:1.
Type:
Grant
Filed:
April 16, 2015
Date of Patent:
January 29, 2019
Assignees:
INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), UNIVERSITE DE BORDEAUX, UNIVERSITE DE RENNES, ECOLE DES HAUTES ETUDES EN SANTE PUBLIQUE (EHESP), UNIVERSITE DES ANTILLES ET DE LA GUYANE, INSTITUTE BERGONIE, UNIVERSITY OF NOTTINGHAM
Inventors:
Patrick Legembre, Pierre Vacher, Doriane Sanseau, Aubin Penna, Robin Flynn