Patents Assigned to Institute Curie
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Patent number: 11439724Abstract: The invention relates to a device for adsorbing odours comprising an absorbent layer and an adsorbent layer, said adsorbent layer being provided with a material permeable to volatile organic compounds (VOCs) and an adsorbent particulate filler comprising at least one spice. Such a device is particularly useful for adsorbing and masking body odours.Type: GrantFiled: June 23, 2020Date of Patent: September 13, 2022Assignees: Institute Curie, Ecole Superieure De Physique Et De Chimie Industrielle (ESPCI), Ecole Nationale Superieure De Chimie De Paris (ENSCP), Centre National De La Recherche Scientifique, Cemag CareInventors: Aurélie Thuleau, Isabelle Fromantin, Vincent Semetey, José Dugay, Jean-François Le Meur
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Publication number: 20190204266Abstract: An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.Type: ApplicationFiled: October 3, 2018Publication date: July 4, 2019Applicants: INSTITUTE CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)Inventors: Jean-Louis VIOVY, Valessa BARBIER
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Publication number: 20180024095Abstract: An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.Type: ApplicationFiled: May 8, 2017Publication date: January 25, 2018Applicants: INSTITUTE CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N. R.S.)Inventors: Jean-Louis VIOVY, Valessa BARBIER
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Patent number: 9658189Abstract: An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.Type: GrantFiled: May 2, 2016Date of Patent: May 23, 2017Assignees: Institute Curie, Centre National de la Recherche Scientifique (C.N.R.S)Inventors: Jean-Louis Viovy, Valessa Barbier
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Publication number: 20160238557Abstract: An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.Type: ApplicationFiled: May 2, 2016Publication date: August 18, 2016Applicants: INSTITUTE CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N. R.S.)Inventors: Jean-Louis VIOVY, Valessa BARBIER
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Patent number: 9364514Abstract: A chimeric peptide construct having a cell penetrating peptide linked to a pro-apoptotic peptide. The construct can be used for treating a tumor in combination with an anti-tumor agent. Also disclosed is a method for treating a tumor with the chimeric peptide construct and a chemotherapeutic agent.Type: GrantFiled: December 27, 2012Date of Patent: June 14, 2016Assignees: Institute Curie, Universite Pierre et Marie Curie (Paris 6)Inventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin
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Patent number: 9353155Abstract: A cell-penetrating peptide is described. Also described is a pro-apoptotic agent including the cell-penetrating peptide and a pro-apoptotic peptide linked thereto. The pro-apoptotic agent is useful for inhibition of in vitro cell proliferation and for treatment of tumors.Type: GrantFiled: December 27, 2012Date of Patent: May 31, 2016Assignees: Universite Pierre et Marie Curie (Paris 6), Institute CurieInventors: Angelita Rebollo Garcia, Fariba Nemati, Didier Decaudin, Jeronimo Bravo Sicilia, Jesus Maria Fominaya Gutierrez
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Patent number: 9347915Abstract: An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.Type: GrantFiled: February 11, 2015Date of Patent: May 24, 2016Assignees: Institute Curie, Centre National de la Recherche Scientifique (C.N.R.S)Inventors: Jean-Louis Viovy, Valessa Barbier
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Publication number: 20150253285Abstract: An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.Type: ApplicationFiled: February 11, 2015Publication date: September 10, 2015Applicants: INSTITUTE CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S.)Inventors: Jean-Louis VIOVY, Valessa Barbier
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Patent number: 8975328Abstract: An aqueous liquid medium for analyzing, purifying or separating species in an element having walls or for treating the walls of an element. The medium includes at least a polymer consisting of several polymeric segments. The polymer is of the irregular block-copolymer or irregular comb-like polymer type and has on the average at least three junction points between polymeric segments of different chemical or topological nature. The medium may be used in methods for analyzing, purifying or separating species and methods for treating an element to be contacted with a fluid and/or species contained in the fluid during preservation, transport, analysis, purification or separation of the fluid.Type: GrantFiled: August 29, 2007Date of Patent: March 10, 2015Assignee: Institute CurieInventors: Jean-Louis Viovy, Valessa Barbier
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Publication number: 20150010485Abstract: At least one microRNA selected from among hsa-miR-330, hsa-miR-7 and hsa-miR-137, the mature forms thereof, and the precursors thereof, for depigmenting the skin, and an in vitro method for identifying depigmenting compounds, which includes the steps of: a) placing at least one test compound in contact with a sample of melanocytes; b) measuring the expression or activity of at least one microRNA selected from among miR-330, miR-7 and miR-137, the mature forms thereof, and the precursors thereof, in the melanocytes; c) selecting the compounds for which at least 20% activation of the expression or of the activity of at least one of the microRNAs is measured in the melanocytes treated in a) by an element for comparing with the untreated melanocytes.Type: ApplicationFiled: December 18, 2012Publication date: January 8, 2015Applicants: CHANEL PARFUMS BEAUTE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), INSTITUTE CURIE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE - CNRSInventors: Gaelle Saintigny, Christian Mahe, Lionel Larue, Florian Rambow
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Patent number: 8852612Abstract: The present invention concerns an universal polypeptidic carrier for targeting directly or indirectly a molecule to Gb3 receptor expressing cells and having the following formula STxB-Z(n)-Cys, wherein: STxB is the Shiga Toxin B subunit or a functional equivalent thereof, Z is an amino-acid devoided of sulfhydryl group, n being 0, 1 or a polypeptide, Cys is the amino-acid Cysteine, and the use thereof for MHC class I and MHC class II presentation of antigens.Type: GrantFiled: September 29, 2009Date of Patent: October 7, 2014Assignees: Institute Curie, Centre National de la Recherche Scientifique, Institut National de la Sante et de la Recherche Medicale, Universite Pierre et Marie Curie (Paris VI)Inventors: Ludger Johannes, Eric Tartour, Bruno Goud, Wolf Herve Fridman
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Publication number: 20100104480Abstract: A method for treating the surface of a polymerio substrate, including the following steps: providing a first polymeric substrate; contracting at least one part of one face of the first substrate with some liquid solvent system, the liquid solvent system containing at least a first volatile compound and at least a second compound having a low molecular weight and able to swell and/or soften the polymeric material forming the face; letting at least the volatile compound to evaporate from the face of the first substrate and; contracting the so-treated face of first substrate with a third material.Type: ApplicationFiled: December 11, 2007Publication date: April 29, 2010Applicants: Institute Curie, Centre National de la Recherche Scientifique, Fluigent Paris-Biotech-Faculte De MedecineInventors: Jean-Louis Viovy, Jeremie Weber, Dejbani Paul, Laurent Malaquin, Sandrine Miserere
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Patent number: 7632514Abstract: The present invention concerns an universal polypeptidic carrier for targeting directly or indirectly a molecule to Gb3 receptor expressing cells and having the following formula STxB-Z(n)-Cys, wherein: STxB is the Shiga Toxin B subunit or a functional equivalent thereof, Z is an amino-acid devoided of sulfydryl group, n being 0, 1 or a polypeptide, Cys is the amino-acid Cysteine, and the use thereof for MHC class I and MHC class II presentation of antigens.Type: GrantFiled: July 29, 2003Date of Patent: December 15, 2009Assignees: Institute Curie, Centre National de la Recherche Scientifque, Institut National de la Sante et de la Recherche Medicale, Universite Pierre et Marie Curie (Paris VI)Inventors: Ludger Johannes, Eric Tartour, Bruno Goud, Wolf Herve Fridman
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Patent number: 7625573Abstract: The object of the invention is a novel sensitization process for antigen-presenting cells, novel means for implementing the process and novel membrane vesicles possessing immunogenic potency. The invention relates in particular to texosomes (vesicles derived from tumor cells) and dexosomes (vesicles derived from dendritic cells loaded or not with antigens), and their use for the vectorization and presentation of antigens in vitro or in vivo as well as in methods or compositions for the treatment of cancers and infectious, parasitic or autoimmune diseases in particular.Type: GrantFiled: July 2, 2003Date of Patent: December 1, 2009Assignees: Cetre National de la Recherche Scientifique, Institute Curie, Institute Gustave RoussyInventors: Laurence Zitvogel, Graça Raposo, Armelle Regnault, Sebastian Amigorena
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Patent number: 7115608Abstract: The present invention is concerned among others with compounds of formula (1), the N-oxides, the pharmaceutically acceptable addition salts, the quaternary amines and stereochemically isomeric forms thereof, wherein Q is halo, C1-6 alkyl or C2-6 alkenyl; X is (a-2) with q and r being O and Z being O, S or SO; R1 is aryl; R2 is selected from formyl; C1-6alkyloxycarbonylalkyl; Het2; Het2C1-6alkyl, C1-6alkylthio; C1-6alkyl optionally substituted with one or two substituents each independently selected from hydroxy, and halo; R3 is selected from formyl; C1-6alkyl optionally substituted with one or two C1-6alkyloxy; R4 is hydrogen, with HTV inhibiting propertiesType: GrantFiled: September 18, 2001Date of Patent: October 3, 2006Assignees: Centre National de la Recherche Schentifique, Institute CurieInventors: Jérôme Guillemont, Abdellah Benjahad, Dominique Mabire, Chi Hung N'Guyen, David Grierson, Claude Monneret, Emile Bisagni, Gérard Sanz, Laurence Decrane
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Publication number: 20020115633Abstract: The invention relates to a pharmaceutical composition containing an effective amount of ezrin mutated on tyrosine 353, or a functional fragment or derivative thereof, in association with a pharmaceutically acceptable carrier, for use preferably in the prevention and/or treatment of tumors.Type: ApplicationFiled: April 8, 2002Publication date: August 22, 2002Applicant: Institute CurieInventors: Monique Arpin, Tiziana Crepaldi, Alexis Gautreau, Daniel Louvard
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Patent number: 6399584Abstract: The invention relates to a pharmaceutical composition containing an effective amount of ezrin mutated on tyrosine 353, or a functional fragment or derivative thereof, in association with a pharmaceutically acceptable carrier, for use preferably in the prevention and/or treatment of tumors.Type: GrantFiled: March 18, 1998Date of Patent: June 4, 2002Assignees: Institute Curie, Centre National de Recherche ScientfiqueInventors: Monique Arpin, Tiziana Crepaldi, Alexis Gautreau, Daniel Louvard