Patents Assigned to Institute for Molecular Biology &
Biotechnology/FORTH
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Patent number: 6297040Abstract: Disclosed is the DNA sequence of an enzyme which catalyzes the conversion of chitin to chitosan. The enzyme exhibits substantial homology to the rhizobial nodB protein.Type: GrantFiled: July 12, 1999Date of Patent: October 2, 2001Assignee: Institute for Molecular Biology & Biotechnology/FORTHInventors: George Thireos, Dimitri Kafetzopoulos
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Patent number: 6225121Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein (or a portion of a transposase protein). The isolated transposable elements or the isolated DNA sequences being characterized by the ability to hybridize to the DNA sequence of Minos-1. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable are useful in methods for the stable introduction of a DNA sequence of interest into a cell. The invention further relates to transgenic animals, gene tagging and insertional mutagenesis produced by such methods. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the Tc-1 family of transposable elements.Type: GrantFiled: April 27, 1998Date of Patent: May 1, 2001Assignee: Institute of Molecular Biology and Biotechnology/FORTHInventors: Charalambos Savakis, Gerald H. Franz, Athanasios Loukeris, Apostolos G. Klinakis
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Patent number: 6159717Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein (or a portion of a transposase protein). The isolated transposable elements or the isolated DNA sequences being characterized by the ability to hybridize to the DNA sequence of Minos-1. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable are useful in methods for the stable introduction of a DNA sequence of interest into a cell. The invention further relates to transgenic animals produced by such methods. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the Tc-1 family of transposable elements.Type: GrantFiled: November 18, 1998Date of Patent: December 12, 2000Assignee: Institute for Molecular Biology and Biotechnology/ForthInventors: Charalambos Savakis, Gerald H. Franz
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Patent number: 5840865Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein (or a portion of a transposase protein). The isolated transposable elements or the isolated DNA sequences being characterized by the ability to hybridize to the DNA sequence of Minos-1. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable are useful in methods for the stable introduction of a DNA sequence of interest into a cell. The invention further relates to transgenic animals produced by such methods. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the Tc-1 family of transposable elements.Type: GrantFiled: September 20, 1995Date of Patent: November 24, 1998Assignee: Institute of Molecular Biology and Biotechnology/FORTHInventors: Charalambos Savakis, Gerald H. Franz, Athanasios Loukeris
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Patent number: 5525502Abstract: Disclosed is the DNA sequence of an enzyme which catalyzes the conversion of chitin to chitosan. The enxyme exhibits substantial homology to the rhizobial nodB protein.Type: GrantFiled: December 7, 1992Date of Patent: June 11, 1996Assignee: Institute for Molecular Biology & Biotechnology/FORTHInventors: George Thireos, Dimitri Kafetzopoulos
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Patent number: 5348874Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein (or a portion of a transposase protein). The isolated transposable elements or the isolated DNA sequences being characterized by the ability to hybridize to the DNA sequence of Minos 1 under stringent hybridization conditions. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable are useful in methods for the stable introduction of a DNA sequence of interest into a eukaryotic cell. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the Tc-1 family of transposable elements.Type: GrantFiled: September 14, 1992Date of Patent: September 20, 1994Assignee: Institute for Molecular Biology and Biotechnology/FORTHInventors: Charalambos Savakis, Gerald H. Franz, Athanasios Loukeris
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Patent number: 5219749Abstract: Chitin deacetylase, the enzyme that catalyzes the hydrolysis of acetamide groups of N-acetylglucosamine in chitin, was purified to homogeneity from mycelial extracts of the fungus Mucor rouxii. In addition, immunoglobulin specifically reactive with chitin deacetylase has been produced and purified.Type: GrantFiled: October 9, 1991Date of Patent: June 15, 1993Assignee: Institute for Molecular Biology & Biotechnology/FORTHInventors: Vassilis Bouriotis, Dimitri Kafetzopoulos, John Vournakis