Patents Assigned to Institute for Molecular Biology & Biotechnology/FORTH
  • Patent number: 6297040
    Abstract: Disclosed is the DNA sequence of an enzyme which catalyzes the conversion of chitin to chitosan. The enzyme exhibits substantial homology to the rhizobial nodB protein.
    Type: Grant
    Filed: July 12, 1999
    Date of Patent: October 2, 2001
    Assignee: Institute for Molecular Biology & Biotechnology/FORTH
    Inventors: George Thireos, Dimitri Kafetzopoulos
  • Patent number: 6225121
    Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein (or a portion of a transposase protein). The isolated transposable elements or the isolated DNA sequences being characterized by the ability to hybridize to the DNA sequence of Minos-1. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable are useful in methods for the stable introduction of a DNA sequence of interest into a cell. The invention further relates to transgenic animals, gene tagging and insertional mutagenesis produced by such methods. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the Tc-1 family of transposable elements.
    Type: Grant
    Filed: April 27, 1998
    Date of Patent: May 1, 2001
    Assignee: Institute of Molecular Biology and Biotechnology/FORTH
    Inventors: Charalambos Savakis, Gerald H. Franz, Athanasios Loukeris, Apostolos G. Klinakis
  • Patent number: 6159717
    Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein (or a portion of a transposase protein). The isolated transposable elements or the isolated DNA sequences being characterized by the ability to hybridize to the DNA sequence of Minos-1. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable are useful in methods for the stable introduction of a DNA sequence of interest into a cell. The invention further relates to transgenic animals produced by such methods. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the Tc-1 family of transposable elements.
    Type: Grant
    Filed: November 18, 1998
    Date of Patent: December 12, 2000
    Assignee: Institute for Molecular Biology and Biotechnology/Forth
    Inventors: Charalambos Savakis, Gerald H. Franz
  • Patent number: 5840865
    Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein (or a portion of a transposase protein). The isolated transposable elements or the isolated DNA sequences being characterized by the ability to hybridize to the DNA sequence of Minos-1. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable are useful in methods for the stable introduction of a DNA sequence of interest into a cell. The invention further relates to transgenic animals produced by such methods. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the Tc-1 family of transposable elements.
    Type: Grant
    Filed: September 20, 1995
    Date of Patent: November 24, 1998
    Assignee: Institute of Molecular Biology and Biotechnology/FORTH
    Inventors: Charalambos Savakis, Gerald H. Franz, Athanasios Loukeris
  • Patent number: 5525502
    Abstract: Disclosed is the DNA sequence of an enzyme which catalyzes the conversion of chitin to chitosan. The enxyme exhibits substantial homology to the rhizobial nodB protein.
    Type: Grant
    Filed: December 7, 1992
    Date of Patent: June 11, 1996
    Assignee: Institute for Molecular Biology & Biotechnology/FORTH
    Inventors: George Thireos, Dimitri Kafetzopoulos
  • Patent number: 5348874
    Abstract: Disclosed are isolated transposable elements, or isolated DNA sequences which encode a transposase protein (or a portion of a transposase protein). The isolated transposable elements or the isolated DNA sequences being characterized by the ability to hybridize to the DNA sequence of Minos 1 under stringent hybridization conditions. The invention also relates to a purified transposase protein, or peptide fragments thereof, encoded by such DNA sequences. Such transposable are useful in methods for the stable introduction of a DNA sequence of interest into a eukaryotic cell. The sequence information disclosed herein is useful in the design of oligonucleotide primers which are useful for the isolation of related members of the Tc-1 family of transposable elements.
    Type: Grant
    Filed: September 14, 1992
    Date of Patent: September 20, 1994
    Assignee: Institute for Molecular Biology and Biotechnology/FORTH
    Inventors: Charalambos Savakis, Gerald H. Franz, Athanasios Loukeris
  • Patent number: 5219749
    Abstract: Chitin deacetylase, the enzyme that catalyzes the hydrolysis of acetamide groups of N-acetylglucosamine in chitin, was purified to homogeneity from mycelial extracts of the fungus Mucor rouxii. In addition, immunoglobulin specifically reactive with chitin deacetylase has been produced and purified.
    Type: Grant
    Filed: October 9, 1991
    Date of Patent: June 15, 1993
    Assignee: Institute for Molecular Biology & Biotechnology/FORTH
    Inventors: Vassilis Bouriotis, Dimitri Kafetzopoulos, John Vournakis