Patents Assigned to INSTITUTE OF BIOTECHNOLOGY CAS, V.V.I.
  • Development of new monoclonal antibodies recognizing human prostate-specific membrane antigen (PSMA)
    Patent number: 11773182
    Abstract: The presently disclosed subject matter provides compositions and methods comprising isolated antibodies that can recognize human prostate-specific membrane antigen (PSMA). The presently disclosed antibodies can be used to for imaging and therapy of PSMA-expressing cancers, such as prostate cancer, in a subject.
    Type: Grant
    Filed: January 5, 2018
    Date of Patent: October 3, 2023
    Assignees: The Johns Hopkins University, Institute of Biotechnology CAS, V.V.I.
    Inventors: Cyril Barinka, Martin G. Pomper, Zora Novakova, Catherine A. Foss
  • 3,5-BIS(PHENYL)-1H-HETEROARYL DERIVATIVES AS MEDICAMENTS
    Publication number: 20220251124
    Abstract: Compounds of general formula I are disclosed. The meaning of individual substituents is described in the claims. The compounds are useful in treatment of cancers, due to their multi-modal mechanism of action.
    Type: Application
    Filed: June 11, 2020
    Publication date: August 11, 2022
    Applicants: INSTITUTE OF BIOTECHNOLOGY CAS, V.V.I., SMART BRAIN S.R.O.
    Inventors: Jaroslav TRUKSA, Lukas WERNER, Jan STURSA, Kristyna BLAZKOVA, Cristian Adrian SANDOVAL ACUNA