Patents Assigned to INSTITUTE OF BOTANY
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Patent number: 12178174Abstract: The present invention relates to rice grain with thickened aleurone. Also provided is a rice plant comprising at least one genetic variation which reduces the activity of at least one ROS1a gene in the plant. Grain of the invention, or aleurone therefrom, has improved nutritional properties, and hence is particularly useful for human and animal feed products.Type: GrantFiled: June 17, 2022Date of Patent: December 31, 2024Assignees: COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION, INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCESInventors: Ronald Chun Wai Yu, Crispin Alexander Howitt, Philip John Larkin, Chun-Ming Liu, Xiao-Ba Wu, Jinxin Liu
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Patent number: 12171835Abstract: The present disclosure relates to the technical field of medicine, in particular to a furan-aspidospermine dimer or a pharmaceutically acceptable salt thereof, and a preparation method, use and a pharmaceutical composition. In the present disclosure, the furan-aspidospermine dimer or a pharmaceutically acceptable salt thereof can activate an immune response by increasing a proportion of T lymphocytes and enhance a function of the immune response.Type: GrantFiled: March 12, 2022Date of Patent: December 24, 2024Assignees: Kunming Institute of Botany, Chinese Academy of SciencesInventors: Xianghai Cai, Guisheng Zhong, Simeng Zhao, Meifen Bao, Yang Yu
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Publication number: 20240409552Abstract: Guaianolide oligomers 1-4 are represented by structural formula (I), a preparation method thereof, and a pharmaceutical composition thereof and the use thereof. The preparation method includes: the preparation of guaianolide diene via epoxy isomerization from arglabin-DMA, and a Diels-Alder reaction between the diene and sesquiterpenoid or oligomeric sesquiterpenoid containing ?, ?-unsaturated ?-lactone fragments and subsequent deprotection of NMe2 to obtain the guaianolide oligomers. The guaianolide oligomers inhibited the growth of human hepatoma cell lines HepG2, Huh7 and SK-Hep-1, and can form a pharmaceutical composition with a pharmaceutically acceptable carrier or excipient to be used for preparing an antihepatoma drug.Type: ApplicationFiled: September 6, 2022Publication date: December 12, 2024Applicant: KUNMING INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCESInventors: Jijun CHEN, Tianze LI, Yunbao MA, Changan GENG, Xuemei ZHANG
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Publication number: 20240334891Abstract: The present invention relates to rice grain with thickened aleurone. Also provided is a rice plant comprising at least one genetic variation which reduces the activity of at least one ROS1a gene in the plant. Grain of the invention, or aleurone therefrom, has improved nutritional properties, and hence is particularly useful for human and animal feed products.Type: ApplicationFiled: June 11, 2024Publication date: October 10, 2024Applicants: Commonwealth Scientific and Industrial Research Organisation, Institute of Botany, Chinese Academy of SciencesInventors: Ronald Chun Wai Yu, Crispin Alexander Howitt, Philip John Larkin, Chun-Ming Liu, Xiao-Ba Wu, Jinxin Liu
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Patent number: 12049412Abstract: The present disclosure provides vermicompost made of aquatic plants and a preparation method of the vermicompost. The preparation method includes: mixing aquatic plant residues and fresh cow dung according to a proportion, and crushing the aquatic plant residues while stirring until even mixing; adding earthworms to a mixture of the aquatic plant residues and the cow dung, where the earthworms transform the mixture of the aquatic plant residues and the cow dung in a forest at 15-35° C., and moisture in the mixture is maintained at 65-75% in the process; and after 35-45 days, separating the earthworms and vermicompost, and drying the vermicompost to obtain the vermicompost made of aquatic plants.Type: GrantFiled: August 1, 2022Date of Patent: July 30, 2024Assignee: INSTITUTE OF BOTANY JIANGSU PROVINCE AND CASInventors: Jian Cui, Jinfeng Li, Dongrui Yao, Jianwei Cui, Wei Wang, Yajun Chang, Xiaojing Liu
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Patent number: 11930751Abstract: Disclosed is a pollen control dry pollination machine for Abies ziyuanensis, comprising a lever; a side of a top of the lever is fixedly connected with one end of a square tube; another end of the square tube is rotatably connected with a pollination shell; a top of the square tube and a top of the pollination shell are slidably connected with a fan; the pollination shell is internally provided with a pollen box, a pollen outlet cover and a pollination chamber from a top to a bottom in sequence; the pollen box is communicated with the pollen outlet cover; a bottom of the pollination chamber is provided with an opening; an Abies ziyuanensis ovulate strobilus to be pollinated is placed in the pollination chamber; a bottom of the pollination shell is fixedly connected with a rotating opening; the lever is provided with a switch.Type: GrantFiled: December 6, 2022Date of Patent: March 19, 2024Assignee: GUANGXI INSTITUTE OF BOTANY, GUANGXI ZHUANG AUTONOMOUS REGION AND CHINESE ACADEMY OF SCIENCESInventors: Xinghua Hu, Tao Deng, Jiatong Ye, Sha Li, Xiaozhen Zhu, Shixun Huang
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Patent number: 11925146Abstract: The present disclosure provides a cultivation method of morels and belongs to the technical field of cultivation of edible fungi. After nutrient contents that can be metabolized and utilized by morel mycelia are scientifically matched, sterilization treatment of exogenous nutrients is eliminated, and the exogenous nutrients are directly compressed for forming. Formed exogenous nutrient blocks and spawn is sowed and covered with soil, so as to realize a potential difference between “rich” and “poor” nutrients in a physical space. When the spawn germinate to form a mycelium network, the mycelia will enter a nutrient-rich exogenous nutrient area, secrete various extracellular enzymes to decompose and utilize these exogenous nutrient blocks, and transport them to a nutrient-poor mycelium network for storage, so as to complete nutrient assimilation and absorption, and reserve energy for later sexual reproduction.Type: GrantFiled: March 25, 2022Date of Patent: March 12, 2024Assignee: Kunming Institute of Botany, Chinese Academy of SciencesInventors: Xiaofei Shi, Wei Liu, Yingli Cai, Fuqiang Yu
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Publication number: 20240040982Abstract: The present invention relates to cereal grain comprising an aleurone, an embryo, a starchy endosperm and a reduced level and/or activity of a mitochondrial single-stranded DNA binding (mtSSB) polypeptide, a RECA3 polypeptide or a TWINKLE polypeptide. Grain of the invention, or aleurone therefrom, has improved nutritional properties, and hence is particularly useful for human and animal feed products.Type: ApplicationFiled: November 30, 2021Publication date: February 8, 2024Applicants: Commonwealth Scientific and Industrial Research Organisation, Institute of Botany, Chinese Academy of SciencesInventors: Dong-Qi LI, Chun-Ming LIU, Xiao-Ba WU, Xue-Feng YAO, Jin-Xin LIU, Ronald Chun-Wai YU, Crispin Alexander HOWITT, Philip John LARKIN
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Publication number: 20230407416Abstract: The present disclosure provides an identification method of two parents of a Nymphaea hybrid based on sequences of internal transcribed spacer (ITS) and matK, and belongs to the technical field of plant molecular identification. In the present disclosure, the identification method includes: based on Sanger sequencing, obtaining an ITS sequence of a nuclear genome fragment inherited from the two parents and a matK sequence of a chloroplast genome fragment inherited from a maternal line in the Nymphaea hybrid; subjecting ITS and matK sequences downloaded from a GenBank to strict screening, and establishing a database of the ITS and matK sequence of the Nymphaea; aligning ITS and matK sequences of the Nymphaea of the parents to be determined with respective database, and constructing a neighbor-joining tree based on a genetic distance; and checking specific loci to obtain information on male and female parents of the Nymphaea to be determined.Type: ApplicationFiled: May 16, 2023Publication date: December 21, 2023Applicant: Kunming Institute of Botany, CASInventors: Zhengshan He, Junbo Yang, Tingshuang Yi, Jie Cai, Zhenyan Yang, Chunxia Zeng, Jixiong Yang, Jing Yang, Zhirong Zhang, Dezhu Li
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Publication number: 20230225270Abstract: Disclosed is a pollen control dry pollination machine for Abies ziyuanensis, comprising a lever; a side of a top of the lever is fixedly connected with one end of a square tube; another end of the square tube is rotatably connected with a pollination shell; a top of the square tube and a top of the pollination shell are slidably connected with a fan; the pollination shell is internally provided with a pollen box, a pollen outlet cover and a pollination chamber from a top to a bottom in sequence; the pollen box is communicated with the pollen outlet cover; a bottom of the pollination chamber is provided with an opening; an Abies ziyuanensis ovulate strobilus to be pollinated is placed in the pollination chamber; a bottom of the pollination shell is fixedly connected with a rotating opening; the lever is provided with a switch.Type: ApplicationFiled: December 6, 2022Publication date: July 20, 2023Applicant: Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of SciencesInventors: Xinghua HU, Tao DENG, Jiatong YE, Sha LI, Xiaozhen ZHU, Shixun HUANG
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Patent number: 11607417Abstract: The present disclosure relates to a celastrol or a pharmaceutically acceptable salt thereof, and a use thereof in the manufacture of a medicament for preventing and/or treating a cholestatic liver disease or a liver fibrosis.Type: GrantFiled: March 9, 2018Date of Patent: March 21, 2023Assignees: ZHEJIANG CHONGLING TECHNOLOGY CO., LTD., KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCESInventors: Fei Li, Qi Zhao
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Publication number: 20230055502Abstract: The present disclosure provides a cultivation method of morels and belongs to the technical field of cultivation of edible fungi. After nutrient contents that can be metabolized and utilized by morel mycelia are scientifically matched, sterilization treatment of exogenous nutrients is eliminated, and the exogenous nutrients are directly compressed for forming. Formed exogenous nutrient blocks and spawn is sowed and covered with soil, so as to realize a potential difference between “rich” and “poor” nutrients in a physical space. When the spawn germinate to form a mycelium network, the mycelia will enter a nutrient-rich exogenous nutrient area, secrete various extracellular enzymes to decompose and utilize these exogenous nutrient blocks, and transport them to a nutrient-poor mycelium network for storage, so as to complete nutrient assimilation and absorption, and reserve energy for later sexual reproduction.Type: ApplicationFiled: March 25, 2022Publication date: February 23, 2023Applicant: Kunming Institute of Botany, Chinese Academy of SciencesInventors: Xiaofei SHI, Wei Liu, Yingli Cai, Fuqiang Yu
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Publication number: 20230018861Abstract: The present invention relates to rice grain with thickened aleurone. Also provided is a rice plant comprising at least one genetic variation which reduces the activity of at least one ROS1a gene in the plant. Grain of the invention, or aleurone there-from, has improved nutritional properties, and hence is particularly useful for human and animal feed products.Type: ApplicationFiled: June 17, 2022Publication date: January 19, 2023Applicants: Commonwealth Scientific and Industrial Research Organisation, Institute of Botany, Chinese Academy of SciencesInventors: Ronald Chun Wai Yu, Crispin Alexander Howitt, Philip John Larkin, Chun-Ming Liu, Xiao-Ba Wu, Jinxin Liu
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Patent number: 11452272Abstract: The present invention relates to rice grain with thickened aleurone. Also provided is a rice plant comprising at least one genetic variation which reduces the activity of at least one ROS1a gene in the plant. Grain of the invention, or aleurone therefrom, has improved nutritional properties, and hence is particularly useful for human and animal feed products.Type: GrantFiled: November 17, 2016Date of Patent: September 27, 2022Assignees: Commonwealth Scientific and Industrial Research Organisation, Institute of Botany, Chinese Academy of SciencesInventors: Ronald Chun Wai Yu, Crispin Alexander Howitt, Philip John Larkin, Chun-Ming Liu, Xiao-Ba Wu, Jinxin Liu
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Publication number: 20210186986Abstract: The present disclosure relates to a celastrol or a pharmaceutically acceptable salt thereof, and a use thereof in the manufacture of a medicament for preventing and/or treating a cholestatic liver disease or a liver fibrosis.Type: ApplicationFiled: March 9, 2018Publication date: June 24, 2021Applicants: KUNMING INSTITUTE OF BOTANY,THE CHINESE ACADEMY OF SCIENCES, ZHEJIANG CHONGLING TECHNOLOGY CO., LTD.Inventors: Fei Li, Qi Zhao
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Publication number: 20210137965Abstract: The present disclosure relates to the prevention of osteoporosis and specifically relates to an application of xylan (polyxylose) in the preparation of drugs or food for preventing or treating osteoporosis. The present disclosure proves by utilizing high-purity xylan in animal experimentation that xylan significantly improves bone metabolism, increases blood vitamin D, PINP, and BALP levels, reduces blood CTXI and urine hydroxyproline levels, and reduces urinary calcium loss, thus providing the effects of inhibiting bone resorption and promoting bone formation. Compared with animals having cellulose, lignin, pectin, fructan, glucomannan intakes or having no dietary fiber intake, animals having a xylan intake have higher bone mass and bone density and better bone biomechanical properties. Xylan is suitable for further development into the drugs or food for preventing or treating osteoporosis.Type: ApplicationFiled: October 11, 2018Publication date: May 13, 2021Applicant: Guangxi Institute Of Botany, Chinese Academy Of SciencesInventors: Yuheng Zhou, Xiangxiang Qin, Aihua Cai, Haishan Chen, Yifang Lu, Ciyu Li, Hourui Zhang
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Patent number: 10954555Abstract: Anthranilate synthase allele fragments for increasing rice yields and uses thereof. A method of differentiating rice materials with a superior allele associated with high yield includes: (1) detecting a genotype of rice to be detected based on a specific gene fragment; where the specific gene fragmentOsASA1 is located in rice genome, and there are typically two allelic forms of OsASA1, OsASA1_a shown as SEQ ID NO. 1 and OsASA1_b shown as SEQ ID NO. 2; and (2) determining and comparing the average yield of a rice population with a genotype of homozygous OsASA1_b and that of a rice population with a genotype of homozygous OsASA1_a under the same growth conditions in different geographical regions. The rice population with the genotype of homozygous OsASA1_b shows a higher average yield than the rice population with the genotype of homozygous OsASA1_a.Type: GrantFiled: March 12, 2019Date of Patent: March 23, 2021Assignee: Institute of Botany, The Chinese Academy of SciencInventors: Yingqing Lu, Nan Li, Lulu Xie, Yiting Wang, Ruijuan Zhang, Jingdan Chen
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Patent number: 10603345Abstract: The invention provides a pharmaceutical composition for treating a respiratory disease, wherein the pharmaceutical composition comprises one or more components selected from picrinine, vallesamine, scholaricine, and 19-epischolaricine. The pharmaceutical composition has a good protective effect on the respiratory system, and can be used in treatment of a relevant disease.Type: GrantFiled: November 10, 2016Date of Patent: March 31, 2020Assignees: Kunming Institute of Botany, The Chinese Academy of Sciences, Kunming Beiao Technology Company LimitedInventors: Xiaodong Luo, Yunli Zhao, Jianhua Shang, Yaping Liu, Yifen Wang
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Publication number: 20180344792Abstract: The invention provides a pharmaceutical composition for treating a respiratory disease, wherein the pharmaceutical composition comprises one or more components selected from picrinine, vallesamine, scholaricine, and 19-epischolaricine. The pharmaceutical composition has a good protective effect on the respiratory system, and can be used in treatment of a relevant disease.Type: ApplicationFiled: November 10, 2016Publication date: December 6, 2018Applicants: Kunming Institute of Botany, The Chinese Academy of Sciences, Kunming Beiao Technology Company LimitedInventors: Xiaodong Luo, Yunli Zhao, Jianhua Shang, Yaping Liu, Yifen Wang
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Patent number: PP34057Abstract: A new and distinct cultivar of Nelumbo plant named ‘Zhongshan Chanyun’, characterized by its upright to somewhat outwardly spreading plant habit; vigorous growth habit; large dark green-colored leaves; freely flowering habit; large purplish pink-colored ball-shaped flowers with numerous petals and petaloids; flowers that are positioned above the foliar plane on moderately strong and erect peduncles; good garden performance and good postproduction longevity.Type: GrantFiled: January 14, 2021Date of Patent: March 22, 2022Assignees: INSTITUTE OF BOTANY, CHINESE ACADEMY OF SCIENCEInventors: Dongrui Yao, Xiaojing Liu, Fengfeng Du, Linhe Sun, Jinfeng Li