Abstract: The present invention relates to rice grain with thickened aleurone. Also provided is a rice plant comprising at least one genetic variation which reduces the activity of at least one ROS1a gene in the plant. Grain of the invention, or aleurone therefrom, has improved nutritional properties, and hence is particularly useful for human and animal feed products.

Abstract: Guaianolide oligomers 1-4 are represented by structural formula (I), a preparation method thereof, and a pharmaceutical composition thereof and the use thereof. The preparation method includes: the preparation of guaianolide diene via epoxy isomerization from arglabin-DMA, and a Diels-Alder reaction between the diene and sesquiterpenoid or oligomeric sesquiterpenoid containing ?, ?-unsaturated ?-lactone fragments and subsequent deprotection of NMe2 to obtain the guaianolide oligomers. The guaianolide oligomers inhibited the growth of human hepatoma cell lines HepG2, Huh7 and SK-Hep-1, and can form a pharmaceutical composition with a pharmaceutically acceptable carrier or excipient to be used for preparing an antihepatoma drug.

Abstract: The present disclosure provides vermicompost made of aquatic plants and a preparation method of the vermicompost. The preparation method includes: mixing aquatic plant residues and fresh cow dung according to a proportion, and crushing the aquatic plant residues while stirring until even mixing; adding earthworms to a mixture of the aquatic plant residues and the cow dung, where the earthworms transform the mixture of the aquatic plant residues and the cow dung in a forest at 15-35° C., and moisture in the mixture is maintained at 65-75% in the process; and after 35-45 days, separating the earthworms and vermicompost, and drying the vermicompost to obtain the vermicompost made of aquatic plants.

Abstract: Disclosed is a pollen control dry pollination machine for Abies ziyuanensis, comprising a lever; a side of a top of the lever is fixedly connected with one end of a square tube; another end of the square tube is rotatably connected with a pollination shell; a top of the square tube and a top of the pollination shell are slidably connected with a fan; the pollination shell is internally provided with a pollen box, a pollen outlet cover and a pollination chamber from a top to a bottom in sequence; the pollen box is communicated with the pollen outlet cover; a bottom of the pollination chamber is provided with an opening; an Abies ziyuanensis ovulate strobilus to be pollinated is placed in the pollination chamber; a bottom of the pollination shell is fixedly connected with a rotating opening; the lever is provided with a switch.

Abstract: The present disclosure relates to a celastrol or a pharmaceutically acceptable salt thereof, and a use thereof in the manufacture of a medicament for preventing and/or treating a cholestatic liver disease or a liver fibrosis.

Abstract: The present disclosure relates to a celastrol or a pharmaceutically acceptable salt thereof, and a use thereof in the manufacture of a medicament for preventing and/or treating a cholestatic liver disease or a liver fibrosis.

Abstract: The present invention provides novel protein and gene related to flavonoid O-methyltransferase (FOMT) and their uses therefore. The said protein having an amino acid sequence shown in SEQ ID NO: 3, or an amino acid sequence having deletion, substitution or insertion of one or plural amino acids in said amino acid sequence. The said gene comprising the nucleotide sequence shown in SEQ ID NO: 1, or a gene which hybridizes with said gene under stringent conditions and encodes a protein, which has anthocyanin 3?-O-methyltransferase or 3?,5?-O-methyltransferase activity. The present invention also provides a method for obtaining the transgenic plant used the above-mentioned gene.

Abstract: A low-molecular-weight fucosylated glycosaminoglycan (aTFG) containing 2,5-anhydrated talose, alditol, glycosylamine or N-substituted glycosylamine monosaccharide composition thereof, preparation method thereof, pharmaceutical compositions containing the aTFG, and use thereof for preventing and/or treating thrombotic diseases are provided. The aTFG has potent anticoagulant activity targeting at intrinsic coagulation factor Xase, and inhibiting thrombogenesis, and therefore can be used as drugs for preventing and/or treating cardiovascular and cerebrovascular diseases.

Abstract: The invention relates to a use of an urushiol compound (code named GQ-5) in preparation of pharmaceutical compositions for inhibiting Smad3 phosphorylation. We verify that GQ-5 inhibited the interaction of Smad3 with TGF-? type I receptor (T?RI), inhibited subsequent phosphorylation of Smad3, reduced nuclear translocation of Smads complex, and suppressed the transcription of major fibrotic genes such as ?-smooth muscle actin (?-SMA), collagen I and fibronectin. Therefore, GQ-5 could be a potent and selective inhibitor of TGF-?1-induced Smad3 phosphorylation, and be used to prepare pharmaceutical compositions for inhibiting Smad3 phosphorylation.

Abstract: The present invention relates to the application of 5-methyl-1,3-benzenediol or its derivatives represented by Formula I; wherein the constituent variables are as defined herein or pharmaceutical compositions thereof containing them in the preparation of medicines or functional foods. The present studies indicate that 5-methyl-1,3-benzenediol or its derivatives represented by Formula I, wherein the constituent variables are as defined herein or pharmaceutical compositions thereof containing them show more significant antidepressant effects than fluoxetine or imipramine.

Abstract: A new and distinct cultivar of Nelumbo plant named ‘Zhongshan Chanyun’, characterized by its upright to somewhat outwardly spreading plant habit; vigorous growth habit; large dark green-colored leaves; freely flowering habit; large purplish pink-colored ball-shaped flowers with numerous petals and petaloids; flowers that are positioned above the foliar plane on moderately strong and erect peduncles; good garden performance and good postproduction longevity.