Patents Assigned to Institute of Microbiology, Guangdong Academy of Sciences(Guangdong Detection Center of Microbiology)
  • Patent number: 11969457
    Abstract: An application of a skeletal muscle secreted factor Thbs4 in a preparation of a drug for improving systemic glucose and lipid metabolism is provided. According to the present invention, it is found through experiments that Thbs4 increases a body's metabolic rate by activating a beige-like change of white adipose, relieves the metabolic disorder caused by high-fat diet, and reveals its application value in the treatment of the metabolic disorder.
    Type: Grant
    Filed: December 6, 2022
    Date of Patent: April 30, 2024
    Assignee: Institute of Microbiology. Guangdong Academy of Sciences(Guangdong Detection Center of Microbiology)
    Inventor: Liwei Xie
  • Publication number: 20240130375
    Abstract: A mildew-proof composite composition with a synergistic effect as well as a preparation method and application thereof is provided. The mildew-proof composite composition includes the following components in volume fraction: 10 to 50% of cinnamon essential oil, and 50 to 90% of mustard essential oil. The mildew-proof composite composition with the synergistic effect provided by the present invention is blended into a composite essential oil composition with a significant inhibitory effect and strong antibacterial effect through the interactions among the components.
    Type: Application
    Filed: December 21, 2023
    Publication date: April 25, 2024
    Applicant: Institute of Microbiology, Guangdong Academy of Sciences(Guangdong Detection Center of Microbiology)
    Inventors: Xiaobao XIE, Dezan LIU, Wenru LI, Zhiqing ZHANG
  • Publication number: 20240102111
    Abstract: The present invention relates to a molecular marker, a specific primer pair, and an identification method of the high-quality Ganoderma lucidum strain HMGIM-M624. The high-quality Ganoderma lucidum strain HMGIM-M624 was preserved in Guangdong Microbial Culture Collection Center (address: 5th Floor, No. 59 Building of No. 100 Yard, Mid. Xianlie Road, Guangzhou City) with the preservation number of GDMCC No: 60889 on Nov. 7, 2019. The molecular marker is an InDel molecular marker. The high-quality Ganoderma lucidum strain HMGIM-M624 has a base deletion of CATGCTGTA at the 246451th-246460th site of the chromosome sca34. The present invention provides reagents for detecting the molecular marker of the high-quality Ganoderma lucidum strain HMGIM-M624. The reagents can distinguish the high-quality Ganoderma lucidum strain HMGIM-M624 from the other 11 G. lucidum strains for commercial cultivation, thus specifically identifying the high-quality Ganoderma lucidum strain HMGIM-M624.
    Type: Application
    Filed: December 15, 2022
    Publication date: March 28, 2024
    Applicants: INFINITUS (CHINA) COMPANY LTD., INSTITUTE OF MICROBIOLOGY, GUANGDONG ACADEMY OF SCIENCES (GUANGDONG DETECTION CENTER OF MICROBIOLOGY
    Inventors: Xiuying KOU, Xiaoxian WU, Jian TANG, Qingping WU, Huiping HU, Xiaowei LIANG, Manjun CAI, Yizhen XIE, Yuanchao LIU, Lijun ZHUO, Ao WANG, Na DU
  • Publication number: 20230398179
    Abstract: An application of a skeletal muscle secreted factor Thbs4 in a preparation of a drug for improving systemic glucose and lipid metabolism is provided. According to the present invention, it is found through experiments that Thbs4 increases a body's metabolic rate by activating a beige-like change of white adipose, relieves the metabolic disorder caused by high-fat diet, and reveals its application value in the treatment of the metabolic disorder.
    Type: Application
    Filed: December 6, 2022
    Publication date: December 14, 2023
    Applicant: Institute of Microbiology, Guangdong Academy of Sciences (Guangdong Detection Center of Microbiology
    Inventor: Liwei XIE
  • Patent number: 11667586
    Abstract: A method for producing an amino acid liquid fertilizer from waste feathers includes: acquiring an enzymatic hydrolysate by performing enzymolysis on feather powder with a complex enzyme; adding acid protease to the enzymatic hydrolysate for enzymolysis; and acquiring the amino acid liquid fertilizer by performing enzyme inactivation on a filtrate acquired by performing filtering after enzymolysis is completed, wherein the complex enzyme includes keratinase and amino acid peptidase. By adopting this method, the enzymolysis rate of the feathers reaches 80% or above and the prepared amino acid liquid fertilizer contains various kinds of amino acids (17 amino acids); and the content of the amino acid can reach 10.12% (by mass fraction) or above and the content of small peptide reaches 9.39% (by mass fraction), which reach the Chinese standard of the amino acid liquid fertilizers without concentration. Thus, the environmental-friendly amino acid liquid fertilizer can be prepared.
    Type: Grant
    Filed: July 16, 2019
    Date of Patent: June 6, 2023
    Assignees: INSTITUTE OF MICROBIOLOGY, GUANGDONG ACADEMY OF SCIENCES (GUANGDONG DETECTION CENTER OF MICROBIOLOGY), GUANGDONG BOWOTE BIOTECHNOLOGY CO., LTD.
    Inventors: Honghui Zhu, Lian Zhou, Xiaolin Xie, Meibiao Chen, Qing Yao
  • Publication number: 20230148605
    Abstract: An application of geraniol in preparation of formulation for promoting synthesis of Pseudomonas aeruginosa 3OC12-HSL signal molecules is provided. It was found that geraniol slightly inhibits growth of Pseudomonas aeruginosa PAO1 strain, but can significantly promote synthesis of the 3OC12-HSL signal molecules of the bacterium, and thus can be applied to preparation of formulation for promoting synthesis of the Pseudomonas aeruginosa 3OC12-HSL signal molecules.
    Type: Application
    Filed: January 24, 2022
    Publication date: May 18, 2023
    Applicant: Institute of Microbiology, Guangdong Academy of Sciences (Guangdong Detection Center of Microbiology
    Inventors: Xiaobao XIE, Wenru LI, Taohua ZENG, Zhiqing ZHANG, Qingshan SHI
  • Publication number: 20230010612
    Abstract: A use of citronellol in preparing a preparation for promoting an expression of a virulence gene toxA of Pseudomonas aeruginosa is disclosed. It was found that citronellol slightly inhibits the growth of a Pseudomonas aeruginosa PAO1 strain and can promote the transcription of the toxA of Pseudomonas aeruginosa, which can increase the yield of an exotoxin A, namely, an encoded product of toxA. Therefore, citronellol is applicable to the preparation of a preparation for promoting the expression of the virulence gene toxA of Pseudomonas aeruginosa.
    Type: Application
    Filed: October 27, 2021
    Publication date: January 12, 2023
    Applicant: Institute of Microbiology, Guangdong Academy of Sciences(Guangdong Detection Center of Microbiology)
    Inventors: Wenru LI, Xiaobao XIE, Taohua ZENG, Zhiqing ZHANG, Jingxia LIU, Qingshan SHI